Phenoxymethylpenicillin

Sold as Spec-pen vk, Athlone phenoxymethylpenicillin, Metpen, Austell-pen vk, Dezzpen, Dezovek, A-lennon phenoxymethylpenicillin, Len v k, Bio-vk, Novo vk, Gsa-phenoxy-meth-pen s125, Orapen, Betapen, V-k-cillin, Darocillin, Compu-pen, Incil vk s, Incil vk t, Len V.K., Betacillin V.K.

S4Read from the PI-PIL document and verified

C₁₆H₁₈N₂O₅S350.40 g/mol

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Drag to rotate. Structure from PubChem CID 6869.

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Registration

Applicants: 11
Registrations: 29
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Ascendis Pharma (Pty) Ltd	Spec-pen vk	250	320671	Not determined	None
Dezzo Trading 392 (Pty) LtdCertificate held by Shanur Healthcare (Pty) Ltd	Athlone phenoxymethylpenicillin, Dezzpen	125/5 ml, 250/5 ml, 250 mg	330047, 330048, 450348	S4	PI PIL
Austell Pharmaceuticals (Pty) LtdCertificate held by Austell Laboratories (Pty) Ltd	Metpen, Austell-pen vk, Dezovek	125, 250	420038, 420039, 420040, 420041, 450349	S4	PI PIL
Pharmacare limited û woodmeadCancelled	A-lennon phenoxymethylpenicillin, Len v k, Compu-pen, Len V.K.	125 MG/5 ML, 125 mg, 250 mg/5 ML, 250 mg, syrup	A0037, A0038, A0040, A0242, A0315, A0327, G0089, J0301	Not determined	None
Biotech Laboratories (Pty) Ltd	Bio-vk, Novo vk	125 mg / 5 ml, 250 ml/5 ml, 250 mg	A0422, A0423, A0428	Not determined	None
Adcock ingram limitedCancelled	Gsa-phenoxy-meth-pen s125	Not stated	A0542	Not determined	None
Genpharm Pharmaceuticals (1993) (Pty) LtdCancelled	Orapen	125 mg	B0050	Not determined	None
Ranbaxy Pharmaceutical (Pty) Ltd	Betapen	250 mg	B0203	Not determined	None
Alliance Pharma (Pty) Ltd1 of 4 cancelled	V-k-cillin, Incil vk s, Incil vk t	125, 250	D0173, G0144, G0145, G0146	Not determined	None
Hoechst Marion Roussel LtdCancelled	Darocillin	250	D0244	Not determined	None
Be-tabs Pharmaceuticals (Pty) LtdCancelled	Betacillin V.K.	Not stated	W0326	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Spec-pen vk 250 EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250	32067132/20.1.2/0671	Registered	Not determined	None
Athlone phenoxymethylpenicillin 125/5 ML EACH 5,0 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125,0 mg	125/5 ml	33004733/20.1.2/0047	Registered	Not determined	None
Athlone phenoxymethylpenicillin 250/5 ML EACH 5,0 ml SUSPENSION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250/5 ml	33004833/20.1.2/0048	Registered	Not determined	None
Metpen 125 EACH 5,0 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125,0 mg	125Powder for oral solution	42003842/20.1.2/0038Approved 30 January 2026	Registered	S4	PI PIL
Metpen 250 EACH 5,0 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250Powder for oral solution	42003942/20.1.2/0039Approved 30 January 2026	Registered	S4	PI PIL
Austell-pen vk 125 EACH 5,0 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125,0 mg	125Powder for oral solution	42004042/20.1.2/0040Approved 31 March 2025	Registered	S4	PI PIL
Austell-pen vk 250 EACH 5,0 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250Powder for oral solution	42004142/20.1.2/0041Approved 31 March 2025	Registered	S4	PI PIL
Dezzpen 250 EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250 mgTablets	45034845/20.1.2/0348Approved 13 March 2026	Registered	S4	PI PIL
Dezovek 250 EACH TABLET CONTAINS :PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250,0 mg	250	45034945/20.1.2/0349	Registered	Not determined	None
A-lennon phenoxymethylpenicillin 250 mg/5 ML EACH 5 ML SYRUP CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 250 MG PHENOXYMETHYLPENICILLIN	250 mg/5 ML	A0037A/20.1.2/37	Cancelled	Not determined	None
A-lennon phenoxymethylpenicillin 125 mg/5 ML 5 ML OF PREPARED SYRUP PHENOXYMETHYLPENICILLIN POTASSIUM A EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125 MG	125 MG/5 ML	A0038	Cancelled	Not determined	None
A-lennon phenoxymethylpenicillin 250 MG tablets EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250 MG	250 mgTablets	A0040A/20.1.2/40	Cancelled	Not determined	None
Len v k syrup EACH 5 ML SYRUP WHEN RECONSTITUTED CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM A EQUIVALENT TO 125 MG PHENOXYMETHYLPENICILLIN	Syrup	A0242	Cancelled	Not determined	None
Len v k 250 MG tablets EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 250 mg PHENOXYMETHYLPENICILLIN	250 mgTablets	A0315A/20.1.2/315	Cancelled	Not determined	None
Len v k 125 MG tablets EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM A EQUIVALENT TO 125 mg PHENOXYMETHYLPENICILLIN	125 mgTablets	A0327	Cancelled	Not determined	None
Bio-vk 125 MG / 5 ML granules EACH 5,0 ml SUSPENSION CONTAINS :PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125,0 mg	125 mg / 5 mlGranules	A0422A/20.1.2/0422	Registered	Not determined	None
Novo vk granules 250 ml/5 ML EACH 5,0 ml CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM A 318,8 mg	250 ml/5 mlGranules	A0423	Old Medicine	Not determined	None
Bio-vk 250 MG tablets EACH TABLET CONTAINS : PHENOXYMETHYLPENICILLIN POTASSIUM 280 MG EQUIVALENT TO 250 MG PHENOXYMETHYLPENICILLIN	250 mgTablets	A0428A/10.1.2/428	Registered	Not determined	None
Gsa-phenoxy-meth-pen s125 EACH 5 ml CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM A EQUIVALENT TO PHENOXYMETHYLPENICILLIN 125 mg	Not listed	A0542	Cancelled	Not determined	None
Orapen 125 MG tablets* EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN 125,0 mg	125 mgTablets	B0050B/20.1.2/50	Cancelled	Not determined	None
Betapen 250 MG granules EACH 5 ml WHEN DILUTED CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM 250 ,0 mg	250 mgGranules	B0203B/20.1.2/203	Registered	Not determined	None
V-k-cillin EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250 mg	Not listed	D0173D/20.1.2/173	Registered	Not determined	None
Darocillin 250 granules EACH 5 ml SOLUTION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 250 mg PHENOXYMETHYLPENICILLIN	250Granules	D0244D/20.1.2/244	Cancelled	Not determined	None
Compu-pen EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO PHENOXYMETHYLPENICILLIN 250 mg	Not listed	G0089G/20.1.2/89	Cancelled	Not determined	None
Incil vk s 125 EACH 5 ml CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 125 mg PHENOXYMETHYLPENICILLIN	125	G0144G/20.1.2/144	Registered	Not determined	None
Incil vk t 125 EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 125 mg PHENOXYMETHYLPENICILLIN	125	G0145G/20.1.2/145	Registered	Not determined	None
Incil vk t 250 EACH TABLET CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 250 mg PHENOXYMETHYLPENICILLIN	250	G0146G/20.1.2/146	Cancelled	Not determined	None
Len V.K. 250 syrup EACH 5 ml RECONSTITUTED SUSPENSION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 250 mg PHENOXYMETHYLPENICILLIN	250Syrup	J0301J/20.1.2/301	Cancelled	Not determined	None
Betacillin V.K.* EACH 5 ml SOLUION CONTAINS PHENOXYMETHYLPENICILLIN POTASSIUM EQUIVALENT TO 125 mg PHENOXYMETHYLPENICILLIN	Not listed	W0326W/20.1.2/326	Cancelled	Not determined	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Phenoxymethylpenicillin potassium equivalent to phenoxymethylpenicillin

S4: Phenoxymethylpenicillin
- except when intended for the prophylaxis of rheumatic fever.
Consolidated Schedules 06 July 2026, line 7543
S3: Phenoxymethylpenicillin
- when intended for the prophylaxis of rheumatic fever.
Consolidated Schedules 06 July 2026, line 4118

Pharmacological class: Penicillins. (class 20.1.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Metpen 125, Austell Pharmaceuticals (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsMetpen 125, Austell Pharmaceuticals (Pty) Ltd Patient information leaflet (PIL)For patients and carersMetpen 125, Austell Pharmaceuticals (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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