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Palonosetron

Sold as Palonosetron teva, Nocipal, Bevativa, Tronson, Palonosetron fresenius, Palton, Kemoprev iv, Loxonext, Poltazo, Hetnoset, Chemsentron, Palonosetron ascendis, Onicit

S4
Loading the molecular structure
C19H24N2O296.40 g/mol

(3AS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one

Drag to rotate. Structure from PubChem CID 6337614.

Background

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Registration

Applicants
11
Registrations
13
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Teva Pharmaceuticals (Pty) LtdPalonosetron teva0,25 mg491130Not determinedPIPIL
Cipla Medpro (Pty) LtdNocipal250 μg/ 5 mL500752Not determinedPIPIL
Macleods Pharmaceuticals SA (Pty) LtdBevativaNot stated510250Not determinedNone
Eurolab (Pty) LtdCancelledTronsonNot stated520020S4None
Fresenius Kabi South Africa (Pty) LtdPalonosetron fresenius0,05 mg/mL520099S4PIPIL
Activo Health (Pty) LtdPaltonNot stated520344Not determinedNone
Austell Pharmaceuticals (Pty) LtdKemoprev iv250 μg530647S4PIPIL
Hetero Drugs South Africa (Pty) LtdLoxonext, Poltazo, HetnosetNot stated540289, 540290.289, 540291.289Not determinedNone
Juno Pharma SA (Pty) LtdCertificate held by Kahma Biotech (Pty) LtdChemsentron250,0 μg550344S4PIPIL
Ascendis Pharma (Pty) LtdPalonosetron ascendis250560440Not determinedNone
Biomab Innovation (Pty) LtdCertificate held by Pfizer Laboratories (Pty) LtdOnicit1ML / 5MLA400322S4PIPIL

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Palonosetron 0,25 teva

Each vial of 5 ml of solution contains PALONOSETRON (AS HYDROCHLORIDE) 0,25 mg

0,25 mgSolution for injection;49113049/5.10/1130Approved 23 February 2023RegisteredNot determinedPIPIL
Nocipal250 μg/ 5 mLSolution for injection50075250/5.10/0752Approved 9 December 2022RegisteredNot determinedPIPIL
Bevativa

EACH 5,0 ml VIAL CONTAINS PALONOSETRON (AS HYDROCHLORIDE) 0,25 mg

Not listed51025051/5.10/0250RegisteredNot determinedNone
Tronson

EACH 5,0 ml SOLUTION CONTAINS PALONOSETRON HYDROCHLORIDE 250,0 ug

Not listed52002052/5.10/0020CancelledS4None
Palonosetron 0,05 mg/ml fresenius0,05 mg/mLSolution for injection52009952/5.10/0099Approved 12 April 2022RegisteredS4PIPIL
Palton

Each 5ml contains PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 250,0 mcg

Not listed52034452/5.10/0344RegisteredNot determinedNone
Kemoprev iv

PALONOSETRON HYDROCHLORIDE

250 μgSolution for injection or infusion53064753/5.10/0647Approved 21 February 2023RegisteredS4PIPIL
Loxonext

EACH VIAL CONTAINS PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 0,25 mg

Not listed54028954/5.10/0289RegisteredNot determinedNone
Poltazo

EACH VIAL CONTAINS PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 0,25 mg

Not listed540290.28954/5.10/0290.289RegisteredNot determinedNone
Hetnoset

EACH VIAL CONTAINS PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 0,25 mg

Not listed540291.28954/5.10/0291.289RegisteredNot determinedNone
Chemsentron

PALONOSETRON HYDROCHLORIDE

250,0 μgSolution for injection55034455/5.10/0344Approved 29 November 2022RegisteredS4PIPIL
Palonosetron 250 ascendis

EACH 5,0 ml SOLUTION CONTAINS PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 250,0 µg

25056044056/5.10/0440RegisteredNot determinedNone
Onicit

EACH 1,0 ml SOLUTION CONTAINS PALONOSETRON HYDROCHLORIDE EQUIVALENT TO PALONOSETRON 50,0 ug

1ML / 5MLSolution for injectionA400322A40/5.10/0322Approved 13 June 2014RegisteredS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Palonosetron hydrochloride

  • S4: Palonosetron

    Consolidated Schedules 06 July 2026, line 7461

Pharmacological class: Serotonin antagonists. (class 5.10)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsPalonosetron 0,25 teva, Teva Pharmaceuticals (Pty) LtdPatient information leaflet (PIL)For patients and carersPalonosetron 0,25 teva, Teva Pharmaceuticals (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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