Olanzapine
Sold as Zyprexa, Zyprexa im, Olexar, Zyprexa velotab, Redilanz, Oleanz rapitab, Oleanz, Zolanz, Adco olanzapine, Olaskit, Olanzapine MSQ, Prexolan, Prexolan im, Zylena, Zylena odt, Olawin orodispersible, Prexolan odt, Olandus, Olawin, Mylan olanzapine, Redilanz odt, DRL olanzapine odt, Zipola, Nezolap, Nezolap odt, Olzacad odt, Orozyp odt
2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Drag to rotate. Structure from PubChem CID 135398745.
Background
Registration
- Applicants
- 17
- Registrations
- 74
- Schedule source
- SAHPRA documentation
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Equity Pharmaceutical (Pty) LtdCertificate held by Eli lilly, Equity Pharmaceuticals (Pty) Ltd. | Zyprexa, Zyprexa im, Zyprexa velotab | 2,5, 5 mg, 10.0 mg, 10 mg | 310058, 310060, 320685, 350307, 380030, 380073 | S5 | PIPIL |
| Cipla Medpro (Pty) Ltd | Olexar | 2,5, 5, 10 | 370316, 370317, 370318 | S5 | None |
| Dr Reddyæs Laboratories (Pty) LtdCertificate held by Dr. Reddy’s Laboratories (Pty) Ltd.1 of 7 cancelled | Redilanz, Redilanz odt, DRL olanzapine odt | 2,5, 5, 10, 15 | 420814, 420815, 420816, 420817, 450323, 450324, 450326 | S5 | PI |
| Ranbaxy (SA) (Pty) Ltd2 of 4 cancelled | Oleanz rapitab, Oleanz | 5, 10 | 430069, 430070, 430327, 430328 | S5 | None |
| Ranbaxy Pharmaceutical (Pty) LtdCancelled | Oleanz | 2,5 | 430326 | S5 | None |
| Zydus Healthcare (Pty) Ltd | Zolanz | 5, 10 | 430666, 430667 | S5 | None |
| Adcock ingram limited2 of 3 cancelled | Adco olanzapine | 2,5, 5, 10 | 430685, 430686, 430687 | S5 | None |
| Trinity Pharma (Pty) Ltd | Olaskit | 2,5, 5, 10 | 430870, 430871, 430872 | S5 | None |
| LHC Pharmaceuticals (Pty) Ltd | Olanzapine MSQ | 2,5, 5, 10 | 430873, 430874, 430875 | S5 | None |
| Pharmacare limited û woodmead | Prexolan, Prexolan im, Prexolan odt | 2,5, 5, 10, 15, 20 | 430908, 430909, 430910, 430911, 440915, 440916, 440917, 440918 | S5 | None |
| Ascendis Pharma (Pty) Ltd | Zylena, Zylena odt | 5, 10, 15, 20 | 440447, 440448, 440449, 440450, 440451, 440452, 440453, 440454 | S5 | None |
| Zentiva South Africa (Pty) LtdCancelled | Olawin orodispersible, Olawin | 5 mg, 10 mg | 440855, 441020 | S5 | None |
| Arya Pharma (Pty) Ltd | Olandus | 2,5, 5, 10 | 440977, 440978, 440979 | S5 | None |
| Viatris Healthcare (Pty) Ltd | Mylan olanzapine | 2,5 mg, 5 mg, 10 mg | 450166, 450167, 450168 | S5 | None |
| Jubilant Pharma SA (Pty) Ltd | Zipola, Olzacad odt | 2,5, 5, 10, 15, 20 | 460667, 460668, 460669, 490264, 490265, 490266, 490267 | S5 | None |
| Macleods Pharmaceuticals SA (Pty) Ltd | Nezolap, Nezolap odt | 2,5 mg, 5 mg, 10 mg, 15 mg, 20 mg | 470284, 470285, 470286, 480343, 480344, 480345, 480346 | S5 | None |
| Forrester Pharma (Pty) Ltd | Orozyp odt | 5, 10, 15, 20 | 500304, 500305, 500306, 500307 | S5 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Zyprexa 5 EACH TABLET CONTAINS OLANZAPINE 5 mg | 5Tablet, injection | 31005831/2.6.5/0058Approved 1 September 2006 | Registered | S5 | PI |
| Zyprexa 10 EACH TABLET CONTAINS OLANZAPINE 10 mg | 10Tablet, injection | 31006031/2.6.5/0060Approved 1 September 2006 | Registered | S5 | PI |
| Zyprexa 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5Tablet, injection | 32068532/2.6.5/0685Approved 1 September 2006 | Registered | S5 | PI |
| Zyprexa im EACH VIAL CONTAINS OLANZAPINE 10,0 mg | 10.0 mgPowder for solution for injection | 35030735/2.6.5/0307Approved 1 February 2022 | Registered | S5 | PIPIL |
| Olexar 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 37031637/2.6.5/0316 | Registered | S5 | None |
| Olexar-5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 37031737/2.6.5/0317 | Registered | S5 | None |
| Olexar-10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 37031837/2.6.5/0318 | Registered | S5 | None |
| Zyprexa velotab 5 MG EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 mg | 38003038/2.6.5/0030 | Registered | S5 | None |
| Zyprexa velotab 10 MG EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 mg | 38007338/2.6.5/0073 | Registered | S5 | None |
| Redilanz 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5Film-coated tablets | 42081442/2.6.5/0814Approved 25 May 2015 | Registered | S5 | PI |
| Redilanz 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5Film-coated tablets | 42081542/2.6.5/0815Approved 25 May 2015 | Registered | S5 | PI |
| Redilanz 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10Film-coated tablets | 42081642/2.6.5/0816Approved 25 May 2015 | Registered | S5 | PI |
| Redilanz 15 EACH TABLET CONTAINS OLANZAPINE 15,0 mg | 15Film-coated tablets | 42081742/2.6.5/0817Approved 25 May 2015 | Registered | S5 | PI |
| Oleanz rapitab 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 43006943/2.6.5/0069 | Registered | S5 | None |
| Oleanz rapitab 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 43007043/2.6.5/0070 | Registered | S5 | None |
| Oleanz 2,5 EACH TABLET CONTAINS: OLANZAPINE 2,5 mg | 2,5 | 43032643/2.6.5/0326 | Cancelled | S5 | None |
| Oleanz 5 EACH TABLET CONTAINS: OLANZAPINE 5,0 mg | 5 | 43032743/2.6.5/0327 | Cancelled | S5 | None |
| Oleanz 10 EACH TABLET CONTAINS: OLANZAPINE 10,0 mg | 10 | 43032843/2.6.5/0328 | Cancelled | S5 | None |
| Zolanz 5 tablets EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5Tablets | 43066643/2.6.5/0666 | Registered | S5 | None |
| Zolanz 10 tablets EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10Tablets | 43066743/2.6.5/0667 | Registered | S5 | None |
| Adco olanzapine 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 43068543/2.6.5/0685 | Cancelled | S5 | None |
| Adco olanzapine 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 43068643/2.6.5/0686 | Cancelled | S5 | None |
| Adco olanzapine 10 EACH TABLET CONTAINS OLANZAPINE 10 mg | 10 | 43068743/2.6.5/0687 | Registered | S5 | None |
| Olaskit 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 43087043/2.6.5/0870 | Registered | S5 | None |
| Olaskit 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 43087143/2.6.5/0871 | Registered | S5 | None |
| Olaskit 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 43087243/2.6.5/0872 | Registered | S5 | None |
| Olanzapine 2,5 MSQ EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 43087343/2.6.5/0873 | Registered | S5 | None |
| Olanzapine 5 MSQ EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 43087443/2.6.5/0874 | Registered | S5 | None |
| Olanzapine 10 MSQ EACH TABLET CONTAINS:OLANZAPINE 10,0 mg | 10 | 43087543/2.6.5/0875 | Registered | S5 | None |
| Prexolan 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 43090843/2.6.5/0908 | Registered | S5 | None |
| Prexolan 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 43090943/2.6.5/0909 | Registered | S5 | None |
| Prexolan 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 43091043/2.6.5/0910 | Registered | S5 | None |
| Prexolan im EACH VIAL CONTAINS OLANZAPINE 10,0 mg | Not listed | 43091143/2.6.5/0911 | Registered | S5 | None |
| Zylena 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 44044744/2.6.5/0447 | Registered | S5 | None |
| Zylena 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 44044844/2.6.5/0448 | Registered | S5 | None |
| Zylena 15 EACH TABLET CONTAINS OLANZAPINE 15,0 mg | 15 | 44044944/2.6.5/0449 | Registered | S5 | None |
| Zylena 20 EACH TABLET CONTAINS OLANZAPINE 20,0 mg | 20 | 44045044/2.6.50450 | Registered | S5 | None |
| Zylena 5 odt EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 44045144/2.6.5/0451 | Registered | S5 | None |
| Zylena 10 odt EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 44045244/2.6.5/0452 | Registered | S5 | None |
| Zylena 15 odt EACH TABLET CONTAINS OLANZAPINE 15,0 mg | 15 | 44045344/2.6.5/0453 | Registered | S5 | None |
| Zylena 20 odt EACH TABLET CONTAINS OLANZAPINE 20,0 mg | 20 | 44045444/2.6.5/0454 | Registered | S5 | None |
| Olawin orodispersible 10 MG EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 mg | 44085544/2.6.5/0855 | Cancelled | S5 | None |
| Prexolan odt 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 44091544/2.6.5/0915 | Registered | S5 | None |
| Prexolan odt 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 44091644/2.6.5/0916 | Registered | S5 | None |
| Prexolan odt 15 EACH TABLET CONTAINS OLANZAPINE 15,0 mg | 15 | 44091744/2.6.5/0917 | Registered | S5 | None |
| Prexolan odt 20 EACH TABLET CONTAINS OLANZAPINE 20,0 mg | 20 | 44091844/2.6.5/0918 | Registered | S5 | None |
| Olandus 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 44097744/2.6.5/0977 | Registered | S5 | None |
| Olandus 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 44097844/2.6.5/0978 | Registered | S5 | None |
| Olandus 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 44097944/2.6.5/0979 | Registered | S5 | None |
| Olawin film coated 5 MG EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 mgFilm coated | 44102044/2.6.5/1020 | Cancelled | S5 | None |
| Mylan olanzapine 2,5 MG EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 mg | 45016645/2.6.5/0166 | Registered | S5 | None |
| Mylan olanzapine 5 MG EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 mg | 45016745/2.6.5/0167 | Registered | S5 | None |
| Mylan olanzapine 10 MG EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 mg | 45016845/2.6.5/0168 | Registered | S5 | None |
| Redilanz odt 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 45032345/2.6.5/0323 | Registered | S5 | None |
| Redilanz odt 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 45032445/2.6.5/0324 | Registered | S5 | None |
| DRL olanzapine odt 10 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 10 | 45032645/2.6.5/0326 | Cancelled | S5 | None |
| Zipola 2,5 EACH TABLET CONTAINS OLANZAPINE 2,5 mg | 2,5 | 46066746/2.6.5/0667 | Registered | S5 | None |
| Zipola 5 EACH TABLET CONTAINS OLANZAPINE 5,0 mg | 5 | 46066846/2.6.5/0668 | Registered | S5 | None |
| Zipola 10 EACH TABLET CONTAINS OLANZAPINE 10,0 mg | 10 | 46066946/2.6.5/0669 | Registered | S5 | None |
| Nezolap 2,5 MG Each tablet contains: Olanzapine 2,5 mg | 2,5 mg | 47028447/2.6.5/0284 | Registered | S5 | None |
| Nezolap 5 MG Each tablet contains: Olanzapine 5,0 mg | 5 mg | 47028547/2.6.5/0285 | Registered | S5 | None |
| Nezolap 10 MG Each tablet contains: Olanzapine 10,0 mg | 10 mg | 47028647/2.6.5/0286 | Registered | S5 | None |
| Nezolap odt 5 MG Each tablet contains: Olanzapine 5,0 mg | 5 mg | 48034348/2.6.5/0343 | Registered | S5 | None |
| Nezolap odt 10 MG Each Tablet contains: Olanzapine 10,0 mg | 10 mg | 48034448/2.6.5/0344 | Registered | S5 | None |
| Nezolap odt 15 MG Each Tablet contains : Olanzapine 15,0 mg | 15 mg | 48034548/2.6.5/0345 | Registered | S5 | None |
| Nezolap odt 20 MG Each Tablet contains: Olanzapine 20,0 mg | 20 mg | 48034648/2.6.5/0346 | Registered | S5 | None |
| Olzacad odt 5 Each Tablet Contains: Olanzapine 5 mg | 5 | 49026449/2.6.5/0264 | Registered | S5 | None |
| Olzacad odt 10 Each Tablet Contains: Olanzapine 10 mg | 10 | 49026549/2.6.5/0265 | Registered | S5 | None |
| Olzacad odt 15 Each Tablet Contains: Olanzapine 15 mg | 15 | 49026649/2.6.5/0266 | Registered | S5 | None |
| Olzacad odt 20 Each Tablet Contains: Olanzapine 20 mg | 20 | 49026749/2.6.5/0267 | Registered | S5 | None |
| Orozyp odt 5 Each Tablet Contains: Olanzapine 5 mg | 5 | 50030450/2.6.5/0304 | Registered | S5 | None |
| Orozyp odt 10 Each Tablets contains: Olanzapine 10 mg | 10 | 50030550/2.6.5/0305 | Registered | S5 | None |
| Orozyp odt 15 Each Tablet Contains: Olanzapine 15 mg | 15 | 50030650/2.6.5/0306 | Registered | S5 | None |
| Orozyp odt 20 Each Tablet Contains: Olanzapine 20 mg | 20 | 50030750/2.6.5/0307 | Registered | S5 | None |
Regulatory status
Where S5 sits on the scale
Prescription-only, with tighter controls on repeats.
Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S5, read from the product's PI-PIL leaflet.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.
Consolidated Schedules listings for Olanzapine
S5: Olanzapine
Consolidated Schedules 06 July 2026, line 9594
Pharmacological class: Miscellaneous structures. (class 2.6.5)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Zyprexa 5, Equity Pharmaceutical (Pty) Ltd is scheduled S5 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.