Minocycline
Sold as Sandoz minocycline, Triomin, Minocycline arya, Merck-minocycline, Ranicin, Ranomin, Cyclimycin
(4S,4AS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
Drag to rotate. Structure from PubChem CID 54675783.
Background
Registration
- Applicants
- 7
- Registrations
- 14
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Oethmaan Biosims (Pty) Ltd | Sandoz minocycline | 50, 100 | 280573, 280574 | S4 | None |
| Unimed Healthcare (Pty) Ltd | Triomin | 50, 100 | 300413, 300414 | S4 | None |
| Arya Pharma (Pty) Ltd | Minocycline arya | 50 mg, 100 mg | 310130, 310131 | S4 | None |
| Merck Generics Rsa (Pty) Ltd | Merck-minocycline | 50, 100 | 320543, 320544 | S4 | None |
| Triomed (Pty) Ltd | Ranicin | 50, 100 | 340194, 340195 | S4 | None |
| Innovata pharmaceuticals | Ranomin | 50, 100 | 360055, 360056 | S4 | None |
| Pharmacare limited û woodmead | Cyclimycin | 50, 100 | W0442, W0443 | S4 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Sandoz minocycline 50 EACH TABLET CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 50 mg MINOCYCLINE | 50 | 28057328/20.1.1/0573 | Registered | S4 | None |
| Sandoz minocycline 100 EACH TABLET CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 100 mg MINOCYCLINE | 100 | 28057428/20.1.1/0574 | Registered | S4 | None |
| Triomin 50 EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 50,0 mg MINOCYCLINE | 50 | 30041330/20.1.1/0413 | Registered | S4 | None |
| Triomin 100 EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 100,0 mg MINOCYCLINE | 100 | 30041430/20.1.1/0414 | Registered | S4 | None |
| Minocycline 50 MG arya EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 50 mg | 50 mg | 31013031/20.1.1/0130 | Registered | S4 | None |
| Minocycline 100 MG arya EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 100 mg | 100 mg | 31013131/20.1.1/0131 | Registered | S4 | None |
| Merck-minocycline 50 EACH TABLET CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 50,0 mg | 50 | 32054332/20.1.1/0543 | Registered | S4 | None |
| Merck-minocycline 100 EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 100,0 mg | 100 | 32054432/20.1.1/0544 | Registered | S4 | None |
| Ranicin 50 capsules EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 50,0 mg | 50Capsules | 34019434/20.1.1/0194 | Registered | S4 | None |
| Ranicin 100 capsules EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 100,0 mg | 100Capsules | 34019534/20.1.1/0195 | Registered | S4 | None |
| Ranomin 50 capsules EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 50,0 mg | 50Capsules | 36005536/20.1.1/0055 | Registered | S4 | None |
| Ranomin 100 capsules EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO MINOCYCLINE 100,0 mg | 100Capsules | 36005636/20.1.1/0056 | Registered | S4 | None |
| Cyclimycin-50 EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 50 MG MINOCYCLINE | 50 | W0442W/20.1.1/442 | Registered | S4 | None |
| Cyclimycin - 100 EACH CAPSULE CONTAINS MINOCYCLINE HYDROCHLORIDE EQUIVALENT TO 100 MG MINOCYCLINE | - 100 | W0443W/20.1.1/443 | Registered | S4 | None |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Minocycline hydrochloride equivalent to minocycline
S4: Minocycline
Consolidated Schedules 06 July 2026, line 7146
Pharmacological class: Broad and medium spectrum antibiotics. (class 20.1.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.