Metronidazole

Sold as Eradia, Amzole, Dynametron, Saltermet, Zagyl, A-lennon metronidazole, Adco metronidazole, Nidasall, Genpharm metronidazole, Rozex, Metagyl, Metagyl forte, Metrogel v, Metronidazole b braun, Bio-metronidazole iv, Metronidazole unimed, Flamet, Metronidazole lamar, Metris, Flagyl, Trichazole, Ambral, Metronidazole fresenius, Anaerobyl, Narobic, Metryl, Adco-metronidazole, Metronidazole bliss, Fungimet, Metron, Sandoz metronidazole, Metrazole, Metronidazoel bliss, Nidatron, Adco metrostat, Berazole, Gsa-metronidazole, Bio metronidazole, Bio-metronidazole, Metazol, Bemetrazole, Suprazole, Geozole, Flagyl fc

S4Read from the PI-PIL document and verified

C₆H₉N₃O₃171.15 g/mol

2-(2-Methyl-5-nitroimidazol-1-yl)ethanol

Drag to rotate. Structure from PubChem CID 4173.

Loading Wikipedia summary

Registration

Applicants: 24
Registrations: 61
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Virbac Rsa (Pty) Ltd	Eradia	Not stated	19/27	Not determined	None
Innovata pharmaceuticalsCertificate held by Innovata Pharmaceuticals Pty Ltd	Amzole, Nidasall	200, 400	270008, 280036, 280037	Not determined	PI PIL
Ascendis Pharma (Pty) Ltd	Dynametron, Metris, Fungimet, Sandoz metronidazole, Metazol	200, 400	270347, A400157, S0153, S0230, W0063, W0064	Not determined	None
Adcock ingram limited5 of 7 cancelled	Saltermet, Adco-metronidazole, Adco metronidazole, Nidatron, Adco metrostat, Gsa-metronidazole	200 mg, 400 mg	270394, R0187, R0188, U0199, V0013, V0241, V0242	Not determined	None
Viatris South Africa (Pty) Ltd	Zagyl	Not stated	270421	Not determined	None
Pharmacare limited û woodmead6 of 7 cancelled	A-lennon metronidazole, Trichazole, Metryl	200 mg, 400 mg, infusion, 0,5 g, 1,0 g	270496, 280027, M0194, M0195, R0178, S0049, S0050	Not determined	None
Adcock Ingram Critical Care (Pty) Ltd	Adco metronidazole	500 mg/100 ml	270562	Not determined	None
Alliance Pharma (Pty) LtdCancelled	Genpharm metronidazole, Narobic, Metron	400 mg	290089, R0003, S0204	Not determined	None
Galderma Laboratories S.A. (Pty) LtdCertificate held by Galderma Laboratories South Africa (Pty) Ltd	Rozex	7.5 mg per g	290771	Not determined	PI PIL
Oethmaan Biosims (Pty) Ltd	Metagyl, Metagyl forte	tablets	320218, 320219	Not determined	None
Inova Pharmaceuticals (Pty) Ltd	Metrogel v	Not stated	330243	Not determined	None
B Braun Medical (Pty) LtdCancelled	Metronidazole b braun	500 mg/100 ml	410155	Not determined	None
Biotech Laboratories (Pty) LtdCertificate held by Biotech Laboratories (Pty) Ltd.	Bio-metronidazole iv, Bio metronidazole, Bio-metronidazole	100 ml, 200, 400	420567, V0370, V0371	S4	PI PIL
Unimed Healthcare (Pty) Ltd	Metronidazole unimed	200, 400	450828, 450829	Not determined	None
Dezzo Trading 392 (Pty) Ltd	Flamet, Anaerobyl	200, 400	450830, 450831, R0300, R0301	Not determined	None
Lamar International (Pty) Ltd	Metronidazole lamar	500 mg	600072	S4	PI PIL
Sanofi-aventis South Africa (Pty) LtdCertificate held by Sanofi-aventis South Africa (Pty) Ltd.2 of 3 cancelled	Flagyl, Flagyl fc	200 mg/5 mL, 200, 400	F0050, Z0295, Z0296	S4	PI PIL
Aquila Healthcare (Pty) Ltd	Ambral	Not stated	P0292	Not determined	None
Fresenius Kabi Manufacturing SA (Pty) Ltd	Metronidazole fresenius	500 mg/100 ml	Q0092	Not determined	None
Medicine Developers International (Pty) Ltd2 of 5 cancelled	Anaerobyl, Suprazole, Geozole	250, 500 mg	Q0101, Q0102, Q0103, Y0260, Z0024	Not determined	None
Bliss Pharmaceuticals (Pty) Ltd	Metronidazole bliss, Metronidazoel bliss	200 mg, 400 mg, 500 mg, 1000 mg	S0014, S0015, S0382, S0383	Not determined	None
Pharmacorp (Pty) Ltd	Metrazole	400 mg	S0251	S4	PI PIL
Quatromed limited	Berazole	400 mg	V0200	Not determined	None
Ranbaxy Pharmaceutical (Pty) Ltd	Bemetrazole	Not stated	X0084	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Eradia EACH 1,0 ml SOLUTION CONTAINS METRONIDAZOLE 125,0 mg	Not listed	19/2719/17.4/27	Registered	Not determined	None
Amzole TABLET METRONIDAZOLE 400 MG	Not listed	27000827/20.2.6/0008	Registered	Not determined	None
Dynametron EACH TABLET CONTAINS METRONIDAZOLE 400 mg	Not listed	27034727/20.2.6/0347	Registered	Not determined	None
Saltermet 400 MG EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mg	27039427/20.2.6/0394	Cancelled	Not determined	None
Zagyl* EACH TABLET CONTAINS METRONIDAZOLE 400 mg	Not listed	27042127/20.2.6/0421	Registered	Not determined	None
A-lennon metronidazole 200 MG tablets EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200 mgTablets	27049627/20.2.6/0496	Cancelled	Not determined	None
Adco metronidazole 500 mg/100 ML EACH 100 ml SOLUTION CONTAINS :METRONIDAZOLE 500 mg	500 mg/100 ml	27056227/20.2.6/0562	Registered	Not determined	None
A-lennon metronidazole 400 MG tablets EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mgTablets	28002728/20.2.6/0027	Cancelled	Not determined	None
Nidasall 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200Tablets	28003628/20.2.6/0036Approved 22 October 2025	Registered	Not determined	PI PIL
Nidasall 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400Tablets	28003728/20.2.6/0037Approved 22 October 2025	Registered	Not determined	PI PIL
Genpharm metronidazole 400 MG EACH TABLET CONTAINS METRONIDAZOLE 400 MG	400 mg	29008929/20.2.6/0089	Cancelled	Not determined	None
Rozex gel EACH 1 g CONTAINS METRONIDAZOLE 7,5 mg	7.5 mg per gGel	29077129/13.4.2/0771Approved 19 April 2022	Registered	Not determined	PI PIL
Metagyl tablets EACH TABLET CONTAINS METRONIDAZOLE 200,0 mg	Tablets	32021832/20.2/0218	Registered	Not determined	None
Metagyl forte tablets EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	Tablets	32021932/20.2/0219	Registered	Not determined	None
Metrogel v EACH 1,0 g GEL CONTAINS METRONIDAZOLE 7,5 mg	Not listed	33024333/20.2.6/0243	Registered	Not determined	None
Metronidazole b braun 500 mg/100 ML EACH 100,0 ml SOLUTION CONTAINS METRONIDAZOLE 500,0 mg	500 mg/100 ml	41015541/20.2/0155	Cancelled	Not determined	None
Bio-metronidazole iv EACH 100,0 ml SOLUTION CONTAINS METRONIDAZOLE 500,0 mg	100 mlSolution for infusion.	42056742/20.2/0567Approved 20 October 2025	Registered	S4	PI PIL
Metronidazole 200 unimed EACH TABLET CONTAINS METRONIDAZOLE 200,0 mg	200	45082845/20.2.6/0828	Registered	Not determined	None
Metronidazole 400 unimed EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	400	45082945/20.2.6/0829	Registered	Not determined	None
Flamet 200 EACH TABLET CONTAINS METRONIDAZOLE 200,0 mg	200	45083045/20.2.6/0830	Registered	Not determined	None
Flamet 400 EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	400	45083145/20.2.6/0831	Registered	Not determined	None
Metronidazole 500 mg/100 ML lamar EACH 100,0 ml SOLUTION CONTAINS: METRONIDAZOLE 500,0 mg	500 mgSolution for infusion	60007260/20.2/0072Approved 28 July 2026	Registered	S4	PI PIL
Metris EACH 100,0 ml SOLUTION CONTAINS METRONIDAZOLE 500,0 mg	Not listed	A400157A40/20.2/0157	Registered	Not determined	None
Flagyl suspension EACH 5 ml SUSPENSION CONTAINS:BENZOYL METRONIDAZOLE 320 mg EQUIVALENT TO 200 mg METRONIDAZOLE	200 mg/5 mLSuspension	F0050F/20.2.6/50Approved 3 February 2026	Registered	S4	PI PIL
Trichazole - 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	- 200	M0194M/20.2.6/194	Cancelled	Not determined	None
Trichazole 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	M0195M/20.2.6/195	Cancelled	Not determined	None
Ambral EACH TABLET CONTAINS METRONIDAZOLE 200 mg	Not listed	P0292P/20.2.6/292	Registered	Not determined	None
Metronidazole 500 mg/100 ML fresenius EACH 100,0 ml SOLUTION CONTAINS METRONIDAZOLE 500,0 mg	500 mg/100 ml	Q0092Q/20.2/92	Registered	Not determined	None
Anaerobyl 250 EACH TABLET CONTAINS METRONIDAZOLE 250 mg	250	Q0101Q/20.2.6/0101	Cancelled	Not determined	None
Anaerobyl 500 tablets EACH TABLET CONTAINS METRONIDAZOLE 500,0 mg	500Tablets	Q0102Q/20.2.6/102	Cancelled	Not determined	None
Anaerobyl injection 500 MG EACH TABLET CONTAINS METRONIDAZOLE 500,0 mg	500 mgInjection	Q0103Q/20.2.6/0103	Registered	Not determined	None
Narobic EACH CAPSULE CONTAINS METRONIDAZOLE 200,0 mg	Not listed	R0003R/20.2.6/3	Cancelled	Not determined	None
Metryl infusion EACH 1 ml INFUSION CONTAINS METRONIDAZOLE 5 mg	Infusion	R0178R/20.2.6/178	Registered	Not determined	None
Adco-metronidazole 200 MG EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200 mg	R0187R/20.2.6/187	Registered	Not determined	None
Adco metronidazole 400 MG EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mg	R0188R/20.2.6/188	Registered	Not determined	None
Anaerobyl 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200	R0300R/20.2.6/300	Registered	Not determined	None
Anaerobyl 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	R0301R/20.2.6/301	Registered	Not determined	None
Metronidazole 200 MG bliss EACH TABLET CONTAINS:METRONIDAZOLE 200 mg	200 mg	S0014S/20.2.6/14	Registered	Not determined	None
Metronidazole 400 MG bliss EACH TABLET CONTAINS:METRONIDAZOLE 400 mg	400 mg	S0015S/20.2.6/15	Registered	Not determined	None
Trichazole suppositories 0,5 g EACH SUPPOSITORY CONTAINS METRONIDAZOLE 0,5 g	0,5 gSuppositories	S0049S/20.2/49	Cancelled	Not determined	None
Trichazole suppositories 1,0 g EACH SUPPOSITORY CONTAINS METRONIDAZOLE 1,0 g	1,0 gSuppositories	S0050S/20.2/50	Cancelled	Not determined	None
Fungimet 400 EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	400	S0153S/20.2.6/153	Registered	Not determined	None
Metron EACH CAPSULE CONTAINS METRONIDAZOLE 200 mg	Not listed	S0204S/20.2.6/204	Cancelled	Not determined	None
Sandoz metronidazole 200 EACH TABLET CONTAINS METRONIDAZOLE 200,0 mg	200	S0230S/20.2.6/230	Registered	Not determined	None
Metrazole EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	400 mgTablets	S0251S/20.2.6/251Approved 8 August 2025	Registered	S4	PI PIL
Metronidazole 500 MG bliss EACH SUPPOSITORY CONTAINS METRONIDAZOLE 500 mg	500 mg	S0382S/20.2/382	Registered	Not determined	None
Metronidazoel 1000 MG bliss EACH SUPPOSITORY CONTAINS METRONIDAZOLE 1000 mg	1000 mg	S0383S/20.2/383	Registered	Not determined	None
Nidatron 400 MG EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mg	U0199U/20.2.6/199	Cancelled	Not determined	None
Adco metrostat 400 MG EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mg	V0013V/20.2.6/13	Cancelled	Not determined	None
Berazole 400 MG tablets EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400 mgTablets	V0200V/20.2/200	Registered	Not determined	None
Gsa-metronidazole 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200	V0241V/20.2.6/241	Cancelled	Not determined	None
Gsa-metronidazole 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	V0242V/20.2.6/242	Cancelled	Not determined	None
Bio metronidazole 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200	V0370V/20.2.6/370	Registered	Not determined	None
Bio-metronidazole 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	V0371V/20.2.6/371	Registered	Not determined	None
Metazol 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200	W0063W/20.2.6/63	Registered	Not determined	None
Metazol 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	W0064W/20.2.6/64	Registered	Not determined	None
Bemetrazole TABLETMETRONIDAZOLE 400 MG	Not listed	X0084X/20.2.6/84	Registered	Not determined	None
Suprazole EACH TABLET CONTAINS METRONIDAZOLE 400,0 mg	Not listed	Y0260Y/20.2.6/260	Registered	Not determined	None
Geozole TABLET METRONIDAZOLE A 400 MG	Not listed	Z0024	Old Medicine	Not determined	None
Flagyl fc 200 EACH TABLET CONTAINS METRONIDAZOLE 200 mg	200	Z0295Z/20.2.6/295	Cancelled	Not determined	None
Flagyl fc 400 EACH TABLET CONTAINS METRONIDAZOLE 400 mg	400	Z0296Z/20.2.6/296	Cancelled	Not determined	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Metronidazole

S4: Metronidazole
- intended and registered for use in pigeons in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947 (Act 36 of 1947) and
- intended for human vaginal use, specifically for the treatment of recurrent bacterial vaginosis. (S2)
Consolidated Schedules 06 July 2026, lines 7108 to 7117
S2: Metronidazole
- when intended for human vaginal use, specifically for the treatment of recurrent bacterial vaginosis and except when intended and registered for use in pigeons in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947 (Act 36 of 1947). (S4)
Consolidated Schedules 06 July 2026, lines 2343 to 2345

Pharmacological class: Other than antibiotics. (class 20.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsNidasall 200, Innovata pharmaceuticals Patient information leaflet (PIL)For patients and carersNidasall 200, Innovata pharmaceuticals

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

Loading PubMed articles

Background