Metformin, vildagliptin

Sold as Galvus met, Jalramet, Vysov met, Galtin plus, Metgulvatin, Xyvilin co, Zomvil co, Vilcomet, Vidamace plus, Vileptin co, Vildagliptin/metformin sun pharma, Vildaglymin, Viglymak plus, Vidiabmet, Avilmet, Diamvil, Vildamet, Vilomet, Dagfotin

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

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Registration

Applicants: 12
Registrations: 35
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Novartis South Africa (Pty) Ltd	Galvus met, Jalramet	000 mg 50/1, 50 mg/850 mg, 50 mg/1000 mg, 50/850 mg	431055, 431056, 480729, 480730	S3	None
Sandoz South Africa (Pty) LtdCancelled	Vysov met	000 mg 50/1, 50/850 mg	480731, 480732	S3	None
Teva Pharmaceuticals (Pty) LtdCancelled	Galtin plus	850/ 50, 1000/ 50	520853, 520854	S3	None
Pharmacare limited û woodmead	Metgulvatin	850/50, 1000/50	530098, 530099	S3	None
Trinity Pharma (Pty) Ltd	Xyvilin co, Zomvil co, Vilcomet	50/850	530255, 530257.255, 530259.255	S3	None
Pharma Dynamics (Pty) Ltd	Vidamace plus	50/1000 mg	561180, 561181	S3	None
Ranbaxy (SA) (Pty) Ltd	Vileptin co, Vildagliptin/metformin sun pharma	50/850, 50/1 000	570060, 570061, 570062.060, 570063.061	S3	None
Macleods Pharmaceuticals SA (Pty) Ltd	Vildaglymin, Viglymak plus	50/850, 50/1000	570366, 570367, 570368.366, 570369.367	S3	None
Pharma-q (Pty) Ltd	Vidiabmet	50/850, 50/1 000	590045, 590046	S3	None
Accord Healthcare (Pty) Ltd	Avilmet, Diamvil	50 mg/850 mg, 50 mg/1000 mg, 50 mg 000 mg /1	590248, 590249, 590250.248, 590251.249	S3	None
Innovata pharmaceuticals	Vildamet	50/850, 50/1 000	590253, 590254	S3	None
Hetero Drugs South Africa (Pty) Ltd	Vilomet, Dagfotin	50/850, 50 mg, 850 mg, 1000 mg	590341, 590342, 590343.341, 590344.342	S3	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Galvus met 50 mg/850 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50 mg/850 mg	43105543/21.2/1055	Registered	S3	None
Galvus met 50 mg/1000 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1000,0 mg	50 mg/1000 mg	43105643/21.2/1056	Registered	S3	None
Jalramet 50/850 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg ,METFORMIN HYDROCHLORIDE 850,0 mg	50/850 mg	48072948/21.2/0729	Registered	S3	None
Jalramet 50/1 000 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1000,0 mg	000 mg 50/1	48073048/21.2/0730	Registered	S3	None
Vysov met 50/850 MG EACH TABLET CONTAINS METFORMIN HYDROCHLORIDE 850,0 mgVILDAGLIPTIN 50,0 mg	50/850 mg	48073148/21.2/0731	Cancelled	S3	None
Vysov met 50/1 000 MG EACH TABLET CONTAINS METFORMIN HYDROCHLORIDE 1 000,0 mgVILDAGLIPTIN 50,0 mg	000 mg 50/1	48073248/21.2/0732	Cancelled	S3	None
Galtin plus 1000/ 50 EACH TABLET CONTAINS: METFORMIN HCl 1000,0 mg VILDAGLIPTIN 50,0 mg	1000/ 50	52085352/21.2/0853	Cancelled	S3	None
Galtin plus 850/ 50 EACH TABLET CONTAINS: METFORMIN HCl 850,0 mg VILDAGLIPTIN 50,0 mg	850/ 50	52085452/21.2/0854	Cancelled	S3	None
Metgulvatin 850/50 EACH TABLET CONTAINS: METFORMIN HYDROCHLORIDE 850,0 mg VILDAGLIPTIN 50,0 mg	850/50	53009853/21.2/0098	Registered	S3	None
Metgulvatin 1000/50 EACH TABLET CONTAINS: METFORMIN HYDROCHLORIDE 1000,0 mg VILDAGLIPTIN 50,0 mg	1000/50	53009953/21.2/0099	Registered	S3	None
Xyvilin co 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850	53025553/21.2/0255	Registered	S3	None
Zomvil co 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850	530257.25553/21.2/0257.255	Registered	S3	None
Vilcomet 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850	530259.25553/21.2/0259.255	Registered	S3	None
Vidamace plus Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 850,0 mg	Not listed	56118056/21.2/1180	Registered	S3	None
Vidamace plus 50/1000 MG Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 1000,0 mg	50/1000 mg	56118156/21.2/1181	Registered	S3	None
Vileptin co 50/850 EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850 mg	50/850	57006057/21.2/0060	Registered	S3	None
Vileptin co 50/1 000 EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000 mg	50/1 000	57006157/21.2/00061	Registered	S3	None
Vildagliptin/metformin 50/850 sun pharma EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850 mg	50/850	570062.06057/21.2/0062.060	Registered	S3	None
Vildagliptin/metformin 50/1 000 sun pharma EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000 mg	50/1 000	570063.06157/21.2/0063.061	Registered	S3	None
Vildaglymin 50/850 Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 850,0 mg	50/850	57036657/21.2/0366	Registered	S3	None
Vildaglymin 50/1000 Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 1000,0 mg	50/1000	57036757/21.2/0367	Registered	S3	None
Viglymak plus 50/850 Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 850,0 mg	50/850	570368.36657/21.2/0368.366	Registered	S3	None
Viglymak plus 50/1000 Each Tablet contains: Vildagliptin 50,0 mg, Metformin Hydrochloride 1000,0 mg	50/1000	570369.36757/21.2/0369.367	Registered	S3	None
Vidiabmet 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850	59004559/21.2/0045	Registered	S3	None
Vidiabmet 50/1 000 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000,0 mg	50/1 000	59004659/21.2/0046	Registered	S3	None
Avilmet 50 mg/850 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50 mg/850 mg	59024859/21.2/0248	Registered	S3	None
Avilmet 50 mg/1000 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000,0 mg	50 mg/1000 mg	59024959/21.2/0249	Registered	S3	None
Diamvil 50 mg/850 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50 mg/850 mg	590250.24859/21.2/0250.248	Registered	S3	None
Diamvil 50 mg/1 000 MG EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000,0 mg	50 mg 000 mg /1	590251.24959/21.2/0251.249	Registered	S3	None
Vildamet 50/850 EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850	59025359/21.2/0253	Registered	S3	None
Vildamet 50/1 000 EACH TABLET CONTAINS VILDAGLIPTIN 50,0 mg and METFORMIN HYDROCHLORIDE 1 000,0 mg	50/1 000	59025459/21.2/0254	Registered	S3	None
Vilomet 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850Film-coated tablets	59034159/21.2/0341Approved 27 January 2026	Registered	S3	PI PIL
Vilomet 50/1 000 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000,0 mg	50 mg, 850 mg, 1000 mgFilm-coated tablets	59034259/21.2/0342Approved 27 January 2026	Registered	S3	PI PIL
Dagfotin 50/850 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 850,0 mg	50/850Film-coated tablets	590343.34159/21.2/0343.341Approved 27 January 2026	Registered	S3	PI PIL
Dagfotin 50/1 000 EACH TABLET CONTAINS: VILDAGLIPTIN 50,0 mg METFORMIN HYDROCHLORIDE 1 000,0 mg	50 mg, 850 mg, 1000 mgFilm-coated tablets	590344.34259/21.2/0344.342Approved 27 January 2026	Registered	S3	PI PIL

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, matched to the Consolidated Schedules by ingredient, confidence medium.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Vildagliptin, metformin hydrochloride

S3: Metformin
Consolidated Schedules 06 July 2026, line 3938
S3: Vildagliptin
Consolidated Schedules 06 July 2026, line 4386

Pharmacological class: Oral hypoglycaemics. (class 21.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Vilomet 50/850, Hetero Drugs South Africa (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsVilomet 50/850, Hetero Drugs South Africa (Pty) Ltd Patient information leaflet (PIL)For patients and carersVilomet 50/850, Hetero Drugs South Africa (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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