Losartan

Sold as Cozaar, Zartan, Austell losartan, Loscoz, Lortell, Ciplazar, Losartan unicorn, Lohype, Natrazone, SPEC losartan, Lozaan, Normoten, Annin, Losartan unimed, Hytenza, Sartoc, Losartan macleods, Zaario, Arbilo, Renicard, Los-arb, Losartan hexal

S3Read from the PI-PIL document and verified

C₂₂H₂₃ClN₆O422.90 g/mol

[2-Butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

Drag to rotate. Structure from PubChem CID 3961.

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Registration

Applicants: 19
Registrations: 55
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Organon South Africa (Pty) Ltd	Cozaar	50, 100	290268, 360490	S3	PI PIL
Pharma Dynamics (Pty) Ltd	Zartan	50 mg, 100 mg	410287, 410289	S3	None
Austell Pharmaceuticals (Pty) Ltd	Austell losartan, Lortell	25, 50, 100	410496, 410497, 410498, 410502, 410503, 410517	S3	PI PIL
Acino Pharma (Pty) LtdCancelled	Loscoz	25, 50, 100	410499, 410500, 410501	S3	None
Cipla Medpro (Pty) Ltd1 of 3 cancelled	Ciplazar	25, 50, 100	410820, 410821, 410822	S3	None
Ranbaxy (SA) (Pty) LtdCancelled	Losartan unicorn	25, 50, 100	410982, 410983, 410984	S3	None
MSQ Pharma (Pty) Ltd	Lohype	25, 50, 100	410985, 410986, 410987	S3	None
Specpharm (Pty) LtdCancelled	Natrazone, SPEC losartan	12,5, 25, 50, 100	411070, 411071, 411072, 411073, 411074, 411075, 411076, 411077	S3	None
Ascendis Pharma (Pty) Ltd	Lozaan	12,5 mg, 25 mg, 50 mg, 100 mg	420094, 420095, 420096, 420097	S3	None
Trinity Pharma (Pty) Ltd	Normoten	50, 100	420437, 420438	S3	None
Aurogen South Africa (Pty) Ltd	Annin	25 mg, 50 mg, 100 mg	430493, 430494, 430495	S3	None
Unimed Healthcare (Pty) Ltd	Losartan unimed, Los-arb	25, 50, 100	430496, 430497, 430498, A400063	S3	None
Abex Pharmaceutica (Pty) Ltd	Hytenza	50, 100	430804, 430805	S3	None
Pharmacare limited û woodmead	Sartoc	50, 100	440883, 440884	S3	None
Macleods Pharmaceuticals SA (Pty) Ltd	Losartan macleods	50 mg, 100 mg	460205, 460206	S3	None
Unicorn Pharmaceuticals (Pty) Ltd	Zaario	50, 100	460714, 460715	S3	None
Jubilant Pharma SA (Pty) Ltd	Arbilo	50, 100	460980, 460981	S3	None
Unichem SA (Pty) Ltd	Renicard	50 mg	A390580	S3	PI PIL
Biotech Laboratories (Pty) Ltd	Losartan hexal	50	A400069	S3	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Cozaar 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50 mg	50Tablet	29026829/7.1.3/0268Approved 30 November 2025	Registered	S3	PI PIL
Cozaar 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100Tablet	36049036/7.1.3/0490Approved 30 November 2025	Registered	S3	PI PIL
Zartan 50 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50 mg	41028741/7.1.3/0287	Registered	S3	None
Zartan 100 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100 mg	41028941/7.1.3/0289	Registered	S3	None
Austell losartan 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25Tablets	41049641/7.1.3/0496Approved 9 November 2022	Registered	S3	PI PIL
Austell losartan 50 EACH TABLET CONTAINS :LOSARTAN POTASSIUM 50,0 mg	50Tablets	41049741/7.1.3/0497Approved 9 November 2022	Registered	S3	PI PIL
Austell losartan 100 EACH TABLET CONTAINS: LOSARTAN POTASSIUM 100,0 mg	100Tablets	41049841/7.1.3/0498Approved 9 November 2022	Registered	S3	PI PIL
Loscoz 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	41049941/7.1.3/0499	Cancelled	S3	None
Loscoz 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	41050041/7.1.3/0500	Cancelled	S3	None
Loscoz 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	41050141/7.1.3/0501	Cancelled	S3	None
Lortell-25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25Tablets	41050241/7.1.3/0502Approved 9 November 2022	Registered	S3	PI PIL
Lortell-50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50Tablets	41050341/7.1.3/0503Approved 9 November 2022	Registered	S3	PI PIL
Lortell-100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100Tablets	41051741/7.1.3/0517Approved 9 November 2022	Registered	S3	PI PIL
Ciplazar 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM EQUIVALENT TO LOSARTAN 25,0 mg	25	41082041/7.1.3/0820	Cancelled	S3	None
Ciplazar 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM EQUIVALENT TO LOSARTAN 50,0 mg	50	41082141/7.1.3/0821	Registered	S3	None
Ciplazar 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM EQUIVALENT TO LOSARTAN 100,0 mg	100	41082241/7.1.3/0822	Registered	S3	None
Losartan unicorn 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	41098241/7.1.3/0982	Cancelled	S3	None
Losartan unicorn 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	41098341/7.1.3/0983	Cancelled	S3	None
Losartan unicorn 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	41098441/7.1.3/0984	Cancelled	S3	None
Lohype 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	41098541/7.1.3/0985	Registered	S3	None
Lohype 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	41098641/7.1.3/0986	Registered	S3	None
Lohype 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	41098741/7.1.3/0987	Registered	S3	None
Natrazone 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	41107041/7.1.3/1070	Cancelled	S3	None
Natrazone 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	41107141/7.1.3/1071	Cancelled	S3	None
Natrazone 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	41107241/7.1.3/1072	Cancelled	S3	None
Natrazone 12,5 EACH TABLET CONTAINS LOSARTAN POTASSIUM 12,5 mg	12,5	41107341/7.1.3/1073	Cancelled	S3	None
SPEC losartan 25 EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	41107441/7.1.3/1074	Cancelled	S3	None
SPEC losartan 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	41107541/7.1.3/1075	Cancelled	S3	None
SPEC losartan 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	41107641/7.1.3/1076	Cancelled	S3	None
SPEC losartan 12,5 EACH TABLET CONTAINS LOSARTAN POTASSIUM 12,5 mg	12,5	41107741/7.1.3/1077	Cancelled	S3	None
Lozaan 12,5 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 12,5 mg	12,5 mg	42009442/7.1.3/0094	Registered	S3	None
Lozaan 25 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25 mg	42009542/7.1.3/0095	Registered	S3	None
Lozaan 50 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50 mg	42009642/7.1.3/0096	Registered	S3	None
Lozaan 100 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100 mg	42009742/7.1.3/0097	Registered	S3	None
Normoten 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	42043742/7.1.3/0437	Registered	S3	None
Normoten 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	42043842/7.1.3/0438	Registered	S3	None
Annin 25 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25 mg	43049343/7.1.3/0493	Registered	S3	None
Annin 50 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50 mg	43049443/7.1.3/0494	Registered	S3	None
Annin 100 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100 mg	43049543/7.1.3/0495	Registered	S3	None
Losartan 25 unimed EACH TABLET CONTAINS LOSARTAN POTASSIUM 25,0 mg	25	43049643/7.1.3/0496	Registered	S3	None
Losartan 50 unimed Each Tablet contains : Losartan Potassium 50,0 mg	50	43049743/7.1.3/0497	Registered	S3	None
Losartan 100 unimed EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	43049843/7.1.3/0498	Registered	S3	None
Hytenza 50 EACH TABLET CONTAINS :LOSARTAN POTASSIUM 50,0 mg	50	43080443/7.1.3/0804	Registered	S3	None
Hytenza 100 EACH TABLET CONTAINS: LOSARTAN POTASSIUM 100,0 mg	100	43080543/7.1.3/0805	Registered	S3	None
Sartoc 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	44088344/7.1.3/0883	Registered	S3	None
Sartoc 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	44088444/7.1.3/0884	Registered	S3	None
Losartan macleods 50 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50 mg	46020546/7.1.3/0205	Registered	S3	None
Losartan macleods 100 MG EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100 mg	46020646/7.1.3/0206	Registered	S3	None
Zaario 50 EACH TABLET CONTAINS:LOSARTAN POTASSIUM 50,0 mg	50	46071446/7.1.3/0714	Registered	S3	None
Zaario 100 EACH TABLET CONTAINS:LOSARTAN POTASSIUM 100,0 mg	100	46071546/7.1.3/0715	Registered	S3	None
Arbilo 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	46098046/7.1.3/0980	Registered	S3	None
Arbilo 100 EACH TABLET CONTAINS LOSARTAN POTASSIUM 100,0 mg	100	46098146/7.1.3/0981	Registered	S3	None
Renicard 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50 mgFilm-coated tablets	A390580A39/7.1.3/0580Approved 29 July 2024	Registered	S3	PI PIL
Los-arb 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	A400063A40/7.1.3/0063	Registered	S3	None
Losartan hexal 50 EACH TABLET CONTAINS LOSARTAN POTASSIUM 50,0 mg	50	A400069A40/7.1.3/0069	Registered	S3	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Losartan potassium

S3: Losartan
Consolidated Schedules 06 July 2026, line 3908

Pharmacological class: Other hypotensives. (class 7.1.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Cozaar 50, Organon South Africa (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsCozaar 50, Organon South Africa (Pty) Ltd Patient information leaflet (PIL)For patients and carersCozaar 50, Organon South Africa (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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