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Ruxolitinib (Jakavi, Vobrusta)

Ruxolitinib

Novartis South Africa (Pty) Ltd

S4

Registration

Applicant
Novartis South Africa (Pty) Ltd
Registrations
8
Schedule source
Consolidated Schedules 06 July 2026

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Jakavi 5 MG tablet

EACH TABLET CONTAINS :RUXOLITINIB PHOSPHATE EQUIVALENT TO RUXOLIYINIB 5,0 mg

5 mgTablet48010948/34/0109RegisteredS4None
Jakavi 15 MG tablet

EACH TABLET CONTAINS :RUXOLITINIB 15,0 mg

15 mgTablet48011048/34/0110RegisteredS4None
Jakavi 20 MG tablet

EACH TABLET CONTAINS :RUXOLITINIB 20,0 mg

20 mgTablet48011148/34/0111RegisteredS4None
Vobrusta 5 MG

EACH TABLET CONTAINS :RUXOLITINIB 5,0 mg

5 mg48090048/34/0900RegisteredS4None
Vobrusta 15 MG

EACH TABLET CONTAINS :RUXOLITINIB 15,0 mg

15 mg48090148/34/0901RegisteredS4None
Vobrusta 20 MG

EACH TABLET CONTAINS :RUXOLITINIB 20,0 mg

20 mg48090248/34/0902RegisteredS4None
Jakavi 10 MG

Each Tablet contains: Ruxolitinib Phosphate equivalent to Ruxolitinib 10,0 mg

10 mg52078152/34/0781RegisteredS4None
Vobrusta 10 MG

Each Tablet contains: Ruxolitinib Phosphate equivalent to Ruxolitinib 10,0 mg

10 mg52078252/34/0782RegisteredS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Ruxolitinib phosphate equivalent to ruxolitinib

  • S4: Ruxolitinib

    Consolidated Schedules 06 July 2026, line 7863

Pharmacological class: Complementary Medicines: Health Supplements (class 34)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

C17H18N6306.40 g/mol

(3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile

Drag to rotate. Structure from PubChem CID 25126798.

SAHPRA documents

SAHPRA has not published a professional information or patient information leaflet for this product.

Background

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Research articles

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