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Isoniazid, rifapentine

Sold as Solonex co, Inozi-co, Fripnit plus, Rifapentine/isoniazid adco

S4Read from the PI-PIL document and verified

Combination product

This product contains more than one active ingredient, so it has no single molecular structure.

Background

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Registration

Applicants
3
Registrations
4
Schedule source
SAHPRA documentation

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Macleods Pharmaceuticals SA (Pty) LtdSolonex co, Inozi-co300 mg/300 mg540160, 540161.16S4PIPIL
Pharma Dynamics (Pty) LtdFripnit plus300 mg, 300 mg570157S4PIPIL
Adcock ingram limitedRifapentine/isoniazid adco300/300590601S4PIPIL

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Solonex co

EACH TABLET CONTAINS ISONIAZID 300,0 mg, RIFAPENTINE 300,0 mg

300 mg/300 mgFilm coated tablet54016054/20.2.3/0160Approved 29 August 2023RegisteredS4PIPIL
Inozi-co

EACH TABLET CONTAINS ISONIAZID 300,0 mg RIFAPENTINE 300,0 mg

300 mg/300 mgTablet540161.1654/20.2.3/0161.160Approved 29 August 2023RegisteredS4PIPIL
Fripnit plus

EACH TABLET CONTAINS RIFAPENTINE 300,0 mg ISONIAZID 300,0 mg

300 mg, 300 mgTablet57015757/20.2.3/0157Approved 2 May 2023RegisteredS4PIPIL
Rifapentine/isoniazid 300/300 adco

EACH TABLET CONTAINS RIFAPENTINE 300,0 mg ISONIAZID 300,0 mg

300/300Film coated tablets59060159/20.2.3/0601Approved 25 March 2025RegisteredS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Isoniazid, rifapentine

  • S4: Isoniazid

    Consolidated Schedules 06 July 2026, line 6819

  • S4: Rifapentine

    Consolidated Schedules 06 July 2026, line 7804

Pharmacological class: Tuberculostatics. (class 20.2.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Solonex co, Macleods Pharmaceuticals SA (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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