Irinotecan

Sold as Campto, Sandoz irinotecan, Irenax, Cipla-irinotecan, Irinotas, Accord irinotecan, Irinotecan viatris, Campto csv, Irnocam, Irinotecan safeline, Irinotecan, Irinotecan FKSA, Colocam, Emcure irinotecan, Irocan, * tiracamp, Iritero, Carohet, Onivyde

C₃₃H₃₈N₄O₆586.70 g/mol

[(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate

Drag to rotate. Structure from PubChem CID 60838.

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Registration

Applicants: 16
Registrations: 42
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pfizer Laboratories (Pty) LtdCancelled	Campto, Campto csv	100 mg/5 ml, 300 mg/15 ml	310183, 431067	S4	None
Oethmaan Biosims (Pty) Ltd	Sandoz irinotecan	40, 100	410028, 410029	S4	None
Sandoz South Africa (Pty) LtdCancelled	Irenax	40, 100	410030, 410031	S4	None
Cipla Medpro (Pty) Ltd	Cipla-irinotecan	40 mg/2 ml, 100 mg/5 ml	410049, 410050	S4	None
Eurolab (Pty) Ltd	Irinotas	40, 100	411003, 440024	S4	None
Accord Healthcare (Pty) Ltd	Accord irinotecan	40, 100	411004, 440025	S4	None
Viatris South Africa (Pty) Ltd	Irinotecan viatris	40 mg/2 ml, 100 mg/5 ml	430348, 430349	S4	None
Dr Reddyæs Laboratories (Pty) LtdCancelled	Irnocam	100	440587	S4	None
Safeline Pharmaceuticals (Pty) LtdCancelled	Irinotecan safeline, Irinotecan	40 mg/2 ml, 100 mg/5 ml	450383, 450384	S4	None
Fresenius Kabi South Africa (Pty) Ltd	Irinotecan FKSA	40 mg/2 ml, 100 mg/5 ml, 300 mg/15 ml, 500 mg/25 ml	450915, 450916, 450917, 450918	S4	None
Equity Pharmaceutical (Pty) LtdCertificate held by Equity pharmaceuticals	Colocam	40, 100, 300, 500	460271, 460272, 460273, 460274	S4	PI PIL
Emcure- Pharmaceutical South Africa (Pty) LtdCancelled	Emcure irinotecan	40 mg/2 ml, 100 mg/5 ml	460731, 460732	S4	None
Innovata pharmaceuticals	Irocan	40 mg/2 ml, 100 mg/5 ml, 300 mg/15 ml, 500 mg/25 ml	500947, 500948, 500949, 500950	S4	None
Mc Pharma (Pty) Ltd	* tiracamp	40, 100, 300, 500	550428, 550429, 550430, 550431	S4	None
Hetero Drugs South Africa (Pty) Ltd	Iritero, Carohet	40 mg/2 ml, 100 mg/5 ml, 300 mg/5 ml, 300 mg/15 ml	560829, 560830, 560831, 560832.829, 560833.830, 560834.831	S4	None
Servier Laboratories South Africa (Pty) Ltd	Onivyde	Not stated	570867	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Campto 100 mg/5 ML EACH 5 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE (TRIHYDRATE) EQUIVALENT TO 100 mg IRINOTECAN	100 mg/5 ml	31018331/26/0183	Cancelled	S4	None
Sandoz irinotecan 40 EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 40,0 mg	40	41002841/26/0028	Registered	S4	None
Sandoz irinotecan 100 EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 100,0 mg	100	41002941/26/0029	Registered	S4	None
Irenax 40 EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 40,0 mg	40	41003041/26/0030	Cancelled	S4	None
Irenax 100 EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 100,0 mg	100	41003141/26/0031	Cancelled	S4	None
Cipla-irinotecan 40 mg/2 ML EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 40,0 mg	40 mg/2 ml	41004941/26/0049	Registered	S4	None
Cipla-irinotecan 100 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100 mg/5 ml	41005041/26/0050	Registered	S4	None
Irinotas 40 EACH 2,0 ml VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 40,0 mg	40	41100341/26/1003	Registered	S4	None
Accord irinotecan 40 EACH 2,0 ml VIAL CONTAINS: IRINOTECAN HYDROCHLORIDE 40,0 mg	40	41100441/26/1004	Registered	S4	None
Irinotecan 100 mg/5 ML viatris EACH 5,0 ml VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100 mg/5 ml	43034843/26/0348	Registered	S4	None
Irinotecan 40 mg/2 ML viatris EACH 2,0 ml VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 40,0 mg	40 mg/2 ml	43034943/26/0349	Registered	S4	None
Campto csv 300 mg/15 ML EACH 1,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 20,0 mg	300 mg/15 ml	43106743/26/1067	Cancelled	S4	None
Irinotas 100 EACH 5,0 ml VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100	44002444/26/0024	Registered	S4	None
Accord irinotecan 100 EACH 5,0 ml VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100	44002544/26/0025	Registered	S4	None
Irnocam 100 EACH 5,0 mL VIAL CONTAINS IRINOTECAN HYDROCHLORIDE A 100,0 mg	100	44058744/26/0587	Cancelled	S4	None
Irinotecan safeline 40 mg/2 ML EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE EQUIVALENT TO IRINOTECAN 40,0 mg	40 mg/2 ml	45038345/26/0383	Cancelled	S4	None
Irinotecan 100 mg/5 ML EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE EQUIVALENT TO IRINOTECAN 100,0 mg	100 mg/5 ml	45038445/26/0384	Cancelled	S4	None
Irinotecan FKSA 40 mg/2 ML EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 40,0 mg	40 mg/2 ml	45091545/26/0915	Registered	S4	None
Irinotecan FKSA 100 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100 mg/5 ml	45091645/26/0916	Registered	S4	None
Irinotecan FKSA 300 mg/15 ML EACH 15,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 300,0 mg	300 mg/15 ml	45091745/26/0917	Registered	S4	None
Irinotecan FKSA 500 mg/25 ML EACH 25,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE 500,0 mg	500 mg/25 ml	45091847/26/0918	Registered	S4	None
Colocam 40 EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 40,0 mg	40Infusion	46027146/26/0271Approved 30 September 2016	Registered	S4	PI PIL
Colocam 100 EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 100,0 mg	100Infusion	46027246/26/0272Approved 30 September 2016	Registered	S4	PI PIL
Colocam 300 EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 300,0 mg	300Infusion	46027346/26/0273Approved 30 September 2016	Registered	S4	PI PIL
Colocam 500 EACH VIAL CONTAINS IRINOTECAN HYDROCHLORIDE 500,0 mg	500Infusion	46027446/26/0274Approved 30 September 2016	Registered	S4	PI PIL
Emcure irinotecan 40 mg/2 ML EACH VIAL CONTAINS IRINOTECAN 40,0 mg	40 mg/2 ml	46073146/26/0731	Cancelled	S4	None
Emcure irinotecan 100 mg/5 ML EACH VIAL CONTAINS IRINOTECAN 100,0 mg	100 mg/5 ml	46073246/26/0732	Cancelled	S4	None
Irocan 40 mg/2 ML EACH 2,0 ml SOLUTION CONTAINS :IRINOTECAN 40,0 mg	40 mg/2 ml	50094750/26/0947	Registered	S4	None
Irocan 100 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS: IRINOTECAN 100,0 mg	100 mg/5 ml	50094850/26/0948	Registered	S4	None
Irocan 300 mg/15 ML EACH 15,0 ml SOLUTION CONTAINS :IRINOTECAN 300,0 mg	300 mg/15 ml	50094950/26/0949	Registered	S4	None
Irocan 500 mg/25 ML EACH 25,0 ml SOLUTION CONTAINS :IRINOTECAN 500,0 mg	500 mg/25 ml	50095050/26/0950	Registered	S4	None
* tiracamp 40 EACH VIAL CONTAINS: IRINOTECAN HYDROCHLORIDE 40,0 mg	40	55042855/26/0428	Registered	S4	None
* tiracamp 100 EACH VIAL CONTAINS: IRINOTECAN HYDROCHLORIDE 100,0 mg	100	55042955/26/0429	Registered	S4	None
* tiracamp 300 EACH VIAL CONTAINS: IRINOTECAN HYDROCHLORIDE 300,0 mg	300	55043055/26/0430	Registered	S4	None
* tiracamp 500 EACH VIAL CONTAINS: IRINOTECAN HYDROCHLORIDE 500,0 mg	500	55043155/26/0431	Registered	S4	None
Iritero 40 mg/2 ML EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 40,0 mg	40 mg/2 ml	56082956/26/0829	Registered	S4	None
Iritero 100 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 100,0 mg	100 mg/5 ml	56083056/26/0830	Registered	S4	None
Iritero 300 mg/5 ML EACH 15,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 300,0 mg	300 mg/5 ml	56083156/26/0831	Registered	S4	None
Carohet 40 mg/2 ML EACH 2,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 40,0 mg	40 mg/2 ml	560832.82956/26/0832.829	Registered	S4	None
Carohet 100 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 100,0 mg	100 mg/5 ml	560833.83056/26/0833.830	Registered	S4	None
Carohet 300 mg/15 ML EACH 15,0 ml SOLUTION CONTAINS IRINOTECAN HYDROCHLORIDE TRIHYDRATE 300,0 mg	300 mg/15 ml	560834.83156/26/0834.831	Registered	S4	None
Onivyde EACH 1,0 ml OF CONCENTRATE CONTAINS: IRINOTECAN SUCROSOFATE EQUIVALENT TO IRINOTECAN ANHYDROUS 4,3 mg	Not listed	57086757/26/0867	Registered	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Irinotecan hydrochloride equivalent to irinotecan

S4: Irinotecan
Consolidated Schedules 06 July 2026, line 6806

Pharmacological class: Cytostatic agents (class 26)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Colocam 40, Equity Pharmaceutical (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsColocam 40, Equity Pharmaceutical (Pty) Ltd Patient information leaflet (PIL)For patients and carersColocam 40, Equity Pharmaceutical (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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