Follitropin alfa, lutropin alfa
Sold as Pergoveris r-hfsh/ r-hlh, Pergoveris
Combination product
This product contains more than one active ingredient, so it has no single molecular structure.
Background
Registration
- Applicants
- 1
- Registrations
- 4
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Merck (Pty) Ltd | Pergoveris r-hfsh/ r-hlh, Pergoveris | 150 IU 75 IU, 300 IU/150 IU, 450 IU/225 IU, 900 IU/450 IU | 440781, 540593, 540594, 540595 | S4 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Pergoveris 150 IU r-hfsh/75 IU r-hlh EACH VIAL CONTAINS FOLLITROPIN ALFA 150,0 IU LUTROPIN ALFA 75,0 IU | 150 IU 75 IU | 44078144/21.10/0781 | Registered | S4 | None |
| Pergoveris 300 iu/150 IU EACH 0,48 ml SOLUTION CONTAINS FOLLITROPIN ALFA (r-hFSH) 300,0 IULUTROPIN ALFA (r-hLH) 150,0 IU | 300 IU/150 IU | 54059354/21.10/0593 | Registered | S4 | None |
| Pergoveris 450 iu/225 IU EACH 0,48 ml SOLUTION CONTAINS FOLLITROPIN ALFA (r-hFSH) 450,0 IULUTROPIN ALFA (r-hLH) 225,0 IU | 450 IU/225 IU | 54059454/21.10/0594 | Registered | S4 | None |
| Pergoveris 900 iu/450 IU EACH 0,48 ml SOLUTION CONTAINS FOLLITROPIN ALFA (r-hFSH) 900,0 IULUTROPIN ALFA (r-hLH) 450,0 IU | 900 IU/450 IU | 54059554/21.10/0595 | Registered | S4 | None |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, matched to the Consolidated Schedules by ingredient, confidence medium.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Follitropin alfa, lutropin alfa
S4: Follitropin alfa
Consolidated Schedules 06 July 2026, line 6437
S4: Lutropin alfa
Consolidated Schedules 06 July 2026, line 6980
Pharmacological class: Trophic hormones. (class 21.10)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.