Emtricitabine, tenofovir disoproxil

Sold as Truvada, Tencitab, Tyricten, Truvir, Cipla-tenofovir/emtricitabine, Didivir, Adco emtevir, Temecit, Tenobine, Tenemine, Emtroc, Hetemcit plus, Emtewin, Tenemcom, Duotemtric, Tenem, Emcovir, Emten, Kaidavir, Tremdex, Emtebon, Mytenotrin, Prepetam, Notrifolar, Fobinolar

S4Read from the PI-PIL document and verified

C₉H₁₄N₅O₄P287.21 g/mol

[(2R)-1-(6-Aminopurin-9-yl)propan-2-yl]oxymethylphosphonic acid

Drag to rotate. Structure from PubChem CID 464205.

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Registration

Applicants: 17
Registrations: 25
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pharmacare limited û woodmeadCertificate held by Aspen pharmacare1 of 2 cancelled	Truvada, Tencitab	200mg, 300mg	410171, 430130	S4	PI PIL
Novagen Pharma (Pty) Ltd	Tyricten	200/300 mg	440086	S4	None
Aurobindo Pharma (Pty) Ltd	Truvir	Not stated	440087	S4	None
Cipla Medpro (Pty) LtdCancelled	Cipla-tenofovir/emtricitabine	Not stated	440445	S4	None
Cipla Medpro Manufacturing (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd	Didivir	200 mg / 300 mg	440446	S4	PI PIL
Adcock ingram limited	Adco emtevir, Temecit, Tenobine	Not stated	440835, 440836, 440837	S4	None
Viatris Healthcare (Pty) Ltd	Tenemine, Mytenotrin	300 mg, 200 mg, 300 mg and 200 mg	450112, 510711	S4	PI PIL
Macleods Pharmaceuticals SA (Pty) Ltd	Emtroc, Kaidavir, Tremdex, Emtebon	tablets	470188, 510260, 510261.26, 510262.26	S4	None
Hetero Drugs South Africa (Pty) Ltd	Hetemcit plus	Not stated	470232	S4	None
Zentiva South Africa (Pty) Ltd	Emtewin	Not stated	470304	S4	None
Specpharm (Pty) LtdCancelled	Tenemcom	Not stated	470740	S4	None
Ranbaxy (SA) (Pty) Ltd	Duotemtric	Not stated	480775	S4	None
Innovata pharmaceuticalsCancelled	Tenem	Not stated	490539	S4	None
Barrs Pharmaceutical Industries (Pty) Ltd	Emcovir	Not stated	500242	S4	None
Emcure- Pharmaceutical South Africa (Pty) LtdCertificate held by Emcure Pharmaceuticals SA (Pty) Ltd.	Emten	300 mg, 200 mg	500243	S4	PI PIL
Austell Pharmaceuticals (Pty) Ltd	Prepetam	200mg, 245mg, 300mg	550350	S4	PI PIL
Laurus Generics SA (Pty) Ltd	Notrifolar, Fobinolar	200mg & 300 mg	560896, 570763	Not determined	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Truvada EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE EQUIVALENT TO TENOFOVIR DISOPROXIL 245,0 mg	300mg. 200mgTablet	41017141/20.2.8/0171Approved 27 November 2015	Cancelled	S4	PI PIL
Tencitab EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	43013043/20.2.8/0130	Registered	S4	None
Tyricten 200/300 MG tablets EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	200/300 mgTablets	44008644/20.2.8/0086	Registered	S4	None
Truvir EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	44008744/20.2.8/0087	Registered	S4	None
Cipla-tenofovir/emtricitabine EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	44044544/20.2.8/0445	Cancelled	S4	None
Didivir EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	200 mg / 300 mgFilm-coated tablets	44044644/20.2.8/0446Approved 13 March 2025	Registered	S4	PI PIL
Adco emtevir EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	44083544/20.2.8/0835	Registered	S4	None
Temecit EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	44083644/20.2.8/0836	Registered	S4	None
Tenobine EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	44083744/20.2.8/0837	Registered	S4	None
Tenemine EACH TABLET CONTAINS: TENOFOVIR DISOPROXIL FUMARATE 300,0 mg EMTRICITABINE 200,0 mg	300 mg, 200 mgFilm coated tablet	45011245/20.2.8/0112Approved 5 November 2024	Registered	S4	PI PIL
Emtroc tablets EACH TABLET CONTAINS:EMTRICITABINE 200,0 mg, TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Tablets	47018847/20.2.8/0188	Registered	S4	None
Hetemcit plus EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	47023247/20.2.8/0232	Registered	S4	None
Emtewin EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	47030447/20.2.8/0304	Registered	S4	None
Tenemcom EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	47074047/20.2.8/0740	Cancelled	S4	None
Duotemtric EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	48077548/20.2.8/0775	Registered	S4	None
Tenem EACH TABLET CONTAINS : EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	49053949/20.2.8/0539	Cancelled	S4	None
Emcovir EACH TABLET CONTAINS : EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	50024250/20.2.8/0242	Registered	S4	None
Emten EACH TABLET CONTAINS : EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	300 mg, 200 mg.Tablets	50024350/20.2.8/0243	Registered	S4	PI PIL
Kaidavir EACH TABLET CONTAINS:EMTRICITABINE 200,0 mg; TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	51026051/20.2.8/0260	Registered	S4	None
Tremdex tablets EACH TABLET CONTAINS:EMTRICITABINE 200,0 mg; TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Tablets	510261.2651/20.2.8/0261.260	Registered	S4	None
Emtebon EACH TABLET CONTAIN: EMTRICITABINE 200,0 mg, TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	Not listed	510262.2651/20.2.8/0262.260	Registered	S4	None
Mytenotrin EACH TABLET CONTAINS: TENOFOVIR DISOPROXIL FUMARATE 300,0 mg EMTRICITABINE 200,0 mg	300 mg and 200 mgFilm coated tablet	51071151/20.2.8/0711Approved 22 July 2025	Registered	S4	PI PIL
Prepetam EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE 300,0 mg	300mg. 245mg. 200mgTablet	55035055/20.2.8/0350Approved 10 February 2023	Registered	S4	PI PIL
Notrifolar EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE EQUIVALENT TO TENOFOVIR DISOPROXIL 300,0 mg	200mg & 300 mgFilm-coated tablets.	56089656/20.2.8/0896Approved 25 April 2026	Registered	Not determined	PI PIL
Fobinolar EACH TABLET CONTAINS EMTRICITABINE 200,0 mg TENOFOVIR DISOPROXIL FUMARATE EQUIVALENT TO TENOFOVIR DISOPROXIL 245,0 mg	Not listed	5707635720.2.8/0763	Registered	Not determined	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Emtricitabine, tenofovir disoproxil fumarate equivalent to tenofovir disoproxil

S4: Dolutegravir
Consolidated Schedules 06 July 2026, line 6100
S4: Efavirenz
Consolidated Schedules 06 July 2026, line 6159
S4: Emtricitabine
Consolidated Schedules 06 July 2026, line 6178
S4: Lamivudine
Consolidated Schedules 06 July 2026, line 6850
S4: Tenofovir
Consolidated Schedules 06 July 2026, line 8130

Pharmacological class: Antiviral agents. (class 20.2.8)

Matched through the components Efavirenz, Lamivudine, Emtricitabine, Dolutegravir.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Truvada, Pharmacare limited û woodmead is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsTruvada, Pharmacare limited û woodmead Patient information leaflet (PIL)For patients and carersTruvada, Pharmacare limited û woodmead

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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