Econazole
Sold as Vari-econazole nitrate m/m vaginal, Pevaryl, Gyno-pevaryl, Gyno-pevaryl depot
1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole
Drag to rotate. Structure from PubChem CID 3198.
Background
Registration
- Applicants
- 3
- Registrations
- 7
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Lebasi Pharmaceuticals (Pty) Ltd | Vari-econazole nitrate m/m vaginal | 1 % | 360130 | Not determined | None |
| Adcock ingram limited3 of 4 cancelled | Pevaryl, Gyno-pevaryl, Gyno-pevaryl depot | cream, 150 | H0162, H0166, J0176, R0179 | Not determined | None |
| Janssen Pharmaceutica (Pty) Ltd1 of 2 cancelled | Pevaryl | powder, spray solution | H0163, H0165 | Not determined | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Vari-econazole nitrate 1 % m/m vaginal cream EACH 1,0 g CREAM CONTAINS ECONAZOLE NITRATE 10,0 mg | 1 %Cream | 36013036/18.6/0130 | Registered | Not determined | None |
| Pevaryl cream EACH 100 g CREAM CONTAINS ECONAZOLE NITRATE 1,0 g | Cream | H0162H/13.9.2/162 | Cancelled | Not determined | None |
| Pevaryl powder EACH 100 g POWDER CONTAINS ECONAZOLE NITRATE 1,0 g | Powder | H0163H/13.9.2/163 | Cancelled | Not determined | None |
| Pevaryl spray solution EACH 100 g SOLUTION CONTAINS ECONAZOLE NITRATE 1,0 g | Spray solution | H0165H/13.9.2/165 | Registered | Not determined | None |
| Gyno-pevaryl EACH 100 g CREAM CONTAINS ECONAZOLE NITRATE 1,0 g | Not listed | H0166H/18.6/166 | Cancelled | Not determined | None |
| Gyno-pevaryl 150 EACH VAGINAL SUPPOSITORY CONTAINS ECONAZOLE NITRATE 150 mg | 150 | J0176J/18.6/176 | Registered | Not determined | None |
| Gyno-pevaryl depot EACH OVULE CONTAINS ECONAZOLE NITRATE 150 mg | Not listed | R0179R/18.6/179 | Cancelled | Not determined | None |
Regulatory status
This product is still scheduled by law even when this site could not determine which tier it falls under. The label carries the S number in a square border; ask a pharmacist if you need to know its schedule.
Listings for this ingredient that could not be applied to this product
S4: Econazole
- when intended for application to the skin (S1) and
- when intended for human vaginal use, specifically for the treatment of recurrent vaginal candidiasis. (S1)
Consolidated Schedules 06 July 2026, lines 6145 to 6148
S1: Econazole
- when intended for human vaginal use specifically for the treatment of recurrent vaginal candidiasis; (S4) or
- when intended for application to the skin. (S4)
Consolidated Schedules 06 July 2026, lines 385 to 390
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.