Doxorubicin

Sold as Doxorubicin hcl-faulding, Bio-doxorubicin hydrochloride, Caelyx, Adriblastina csv, Hx-doxorubicin, Cipla-doxorubicin, Doxolip, Doxorubicin accord, Rubexet, Rubidoks, Doxred lyophilized, Doxorubicin "ebewe", Doxopeg, Adriblastina rd, Doxorubicin-sol pch

C₂₇H₂₉NO₁₁543.50 g/mol

(7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

Drag to rotate. Structure from PubChem CID 31703.

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Registration

Applicants: 10
Registrations: 33
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pfizer Laboratories (Pty) LtdCancelled	Doxorubicin hcl-faulding, Adriblastina csv, Adriblastina rd	10 mg, 10 mg/5 ml, 20 mg, 50 mg, 50 mg/25 ml	290672, 290673, 330102, 330104, F0274, F0289, U0183	S4	None
Zimbili Pharma CC	Bio-doxorubicin hydrochloride	10, 50	320507, 320508	S4	None
Baxter Healthcare South Africa (Pty) LtdCertificate held by Janssen Pharmaceutica (Pty.) Ltd.	Caelyx	2 mg/mL	320533	S4	PI PIL
Oethmaan Biosims (Pty) Ltd	Hx-doxorubicin, Doxred lyophilized	10 mg/ 5 ml, 10, 50 mg/ 25 ML, 50	370030, 370031, 570698, 570699	S4	None
Cipla Medpro (Pty) LtdCertificate held by Cipla	Cipla-doxorubicin	10, 50	410034, 410035	S4	PI PIL
Ranbaxy Pharmaceutical (Pty) Ltd	Doxolip	Not stated	430018	S4	None
Accord Healthcare (Pty) Ltd	Doxorubicin accord, Rubexet	10 mg/5 ml, 50 mg/25 ml, 200 mg/100 ml	460484, 460485, 460487, 460488, 460489	S4	None
Innovata pharmaceuticals	Rubidoks	10 mg, 20 mg, 50 mg, 100 mg, 200 mg	530077, 530078, 530079, 530080, 530081	S4	None
Key Oncologics (Pty) Ltd2 of 3 cancelled	Doxorubicin "ebewe", Doxopeg	2 mg, 10 mg, 50 mg	A400352, A400353, A400389	S4	PI PIL
Teva Pharmaceuticals (Pty) Ltd	Doxorubicin-sol pch	10 mg, 50 mg, 200 mg	Z0167, Z0169, Z0170	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Doxorubicin hcl-faulding 10 MG EACH 2 ml CONTAINS DOXORUBICIN HYDROCHLORIDE 10 mg	10 mg	29067229/26/0672	Cancelled	S4	None
Doxorubicin hcl-faulding 50 MG EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50 mg	29067329/26/0673	Cancelled	S4	None
Bio-doxorubicin hydrochloride 10 EACH 10 ml VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10	32050732/26/0507	Registered	S4	None
Bio-doxorubicin hydrochloride 50 EACH 37 ml VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50	32050832/26/0508	Registered	S4	None
Caelyx EACH 1,0 ml CONCENTRATE CONTAINS DOXORUBICIN HYDROCHLORIDE 2,0 mg	2 mg/mLConcentrate for infusion	32053332/26/0533Approved 27 October 2020	Registered	S4	PI PIL
Adriblastina csv 10 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10 mg/5 ml	33010233/26/0102	Cancelled	S4	None
Adriblastina csv 50 mg/25 ML EACH 25,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50 mg/25 ml	33010433/26/0104	Cancelled	S4	None
Hx-doxorubicin 10 mg/ 5 ML EACH 5,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10 mg/ 5 ml	37003037/26/0030	Registered	S4	None
Hx-doxorubicin 50 mg/ 25 ML EACH 25,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50 mg/ 25 ML	37003137/26/0031	Registered	S4	None
Cipla-doxorubicin 10 EACH 5,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10Injection	41003441/26/0034	Registered	S4	PI PIL
Cipla-doxorubicin 50 EACH 25,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50Injection	41003541/26/0035	Registered	S4	PI PIL
Doxolip EACH 1,0 ml SOLUTION CONTAINS: DOXORUBICIN HYDROCHLORIDE 2,0 mg	Not listed	43001843/26/0018	Registered	S4	None
Doxorubicin accord 10 mg/5 ML EACH 1,0 ml SOLUTION CONTAINS :DOXORUBICIN HYDROCHLORIDE 2,0 mg	10 mg/5 ml	46048446/26/0484	Registered	S4	None
Doxorubicin accord 50 mg/25 ML EACH 1,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 2,0 mg	50 mg/25 ml	46048546/26/0485	Registered	S4	None
Rubexet 10 mg/5 ML EACH 5,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10 mg/5 ml	46048746/26/0487	Registered	S4	None
Rubexet 50 mg/25 ML EACH 25,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50 mg/25 ml	46048846/26/0488	Registered	S4	None
Rubexet 200 mg/100 ML EACH 100,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 200,0 mg	200 mg/100 ml	46048946/26/0489	Registered	S4	None
Rubidoks 10 MG EACH VIAL CONTAINS: DOXORUBICIN HYDROCHLORIDE 10,0 mg	10 mg	53007753/26/0077	Registered	S4	None
Rubidoks 20 MG EACH VIAL CONTAINS: DOXORUBICIN HYDROCHLORIDE 20, 0 mg	20 mg	53007853/26/0078	Registered	S4	None
Rubidoks 50 MG EACH VIAL CONTAINS: DOXORUBICIN HYDROCHLORIDE 50, 0 mg	50 mg	53007953/26/0079	Registered	S4	None
Rubidoks 100 MG EACH VIAL CONTAINS: DOXORUBICIN HYDROCHLORIDE 100,0 mg	100 mg	53008053/26/0080	Registered	S4	None
Rubidoks 200 MG EACH VIAL CONTAINS: DOXORUBICIN HYDROCHLORIDE 200,0 mg	200 mg	53008153/26/0081	Registered	S4	None
Doxred 10 lyophilized powder EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10Powder	57069857/26/0698	Registered	S4	None
Doxred 50 lyophilized powder EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50Powder	57069957/26/0699	Registered	S4	None
Doxorubicin "ebewe" 10 MG EACH 5,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 10,0 mg	10 mg	A400352A40/26/0352	Cancelled	S4	None
Doxorubicin "ebewe" 50 MG EACH 25,0 ml SOLUTION CONTAINS DOXORUBICIN HYDROCHLORIDE 50,0 mg	50 mg	A400353A40/26/0353	Cancelled	S4	None
Doxopeg EACH 1,0 ml SUSPENSION CONTAINS DOXORUBICIN HYDROCHLORIDE 2,0 mg	2 mgLiposomal infusion.	A400389A40/26/0389Approved 7 August 2024	Registered	S4	PI PIL
Adriblastina rd 10 MG EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 10 mg	10 mg	F0274F/26/274	Cancelled	S4	None
Adriblastina rd 50 MG EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 50 mg	50 mg	F0289F/26/289	Cancelled	S4	None
Adriblastina rd 20 MG EACH VIAL CONTAINS DOXORUBICIN HYDROCHLORIDE 20 mg	20 mg	U0183U/26/183	Cancelled	S4	None
Doxorubicin-sol pch 10 MG EACH 1 ml CONTAINS DOXORUBICIN HYDROCHLORIDE 2 mg	10 mg	Z0167Z/26/167	Registered	S4	None
Doxorubicin-sol pch 50 MG EACH 1 ml CONTAINS DOXORUBICIN HYDROCHLORIDE 2 mg	50 mg	Z0169Z/26/169	Registered	S4	None
Doxorubicin-sol pch 200 MG EACH 1 ml CONTAINS DOXORUBICIN HYDROCHLORIDE 2 mg	200 mg	Z0170Z/26/170	Registered	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Doxorubicin hydrochloride

S4: Doxorubicin
Consolidated Schedules 06 July 2026, line 6116

Pharmacological class: Cytostatic agents (class 26)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsCaelyx, Baxter Healthcare South Africa (Pty) Ltd Patient information leaflet (PIL)For patients and carersCaelyx, Baxter Healthcare South Africa (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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