Dorzolamide, timolol

Sold as Cosopt, Glauopt co, Dorzotim, Glausol, Ciplasopt co, Soptico, Glaumide-co, Dorzolamide co eye pharma-q, Timdopt, Glautidor, Ocudor co, Eyezolad, Dorzopt forte, Dorzopres forte, Micogloma co, Dorzolamide co adco, Timozera

S3Read from the PI-PIL document and verified

C₁₃H₂₄N₄O₃S316.42 g/mol

(2S)-1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

Drag to rotate. Structure from PubChem CID 33624.

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Registration

Applicants: 14
Registrations: 17
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Mundipharma (Pty) Ltd	Cosopt	20/5 mg	320525	S3	PI PIL
Adcock ingram limited	Glauopt co, Micogloma co, Dorzolamide co adco	Not stated	441052, 560843, 560844.843	Not determined	None
Acino Pharma (Pty) Ltd	Dorzotim	Not stated	450142	Not determined	None
Accord Healthcare (Pty) Ltd	Glausol	Not stated	450673	Not determined	None
Cipla Medpro (Pty) LtdCancelled	Ciplasopt co	Not stated	460269	Not determined	None
Medpro Pharmaceutica (Pty) LtdCancelled	Soptico	Not stated	460270	Not determined	None
Gen-eye (Pty) Ltd	Glaumide-co	20 mg/ml + 5 mg/ml	460684	Not determined	PI PIL
Pharma-q Holdings (Pty) Ltd	Dorzolamide co eye pharma-q	drops	480796	Not determined	None
Activo Health (Pty) Ltd	Timdopt	Not stated	500402	Not determined	None
Forrester Pharma (Pty) Ltd	Glautidor	Not stated	510066	Not determined	None
Pharma Dynamics (Pty) Ltd	Ocudor co	Not stated	510162	Not determined	None
Unicorn Pharmaceuticals (Pty) Ltd	Eyezolad	Not stated	530176	Not determined	None
Austell Pharmaceuticals (Pty) Ltd	Dorzopt forte, Dorzopres forte	20 mg, 5 mg	540257, 540258.257	S3	PI PIL
FDC SA (Pty) Ltd	Timozera	Not stated	561210.1209	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Cosopt EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 22,26 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 6,83 mg	20/5 mgOphthalmic solution	32052532/15.4/0525Approved 15 December 2025	Registered	S3	PI PIL
Glauopt co EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 25,0 mg	Not listed	44105244/15.4/1052	Registered	Not determined	None
Dorzotim EACH 1,0 ml DROPS CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	45014245/15.4/0142	Registered	Not determined	None
Glausol EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	45067345/15.4/0673	Registered	Not determined	None
Ciplasopt co EACH 1,0 ml DROPS CONTAINS DORZOLAMIDE HYDROCHLORIDE 22,26 mg TIMOLOL MALEATE 6,83 mg	Not listed	46026946/15.4/0269	Cancelled	Not determined	None
Soptico EACH 1,0 ml DROPS CONTAINS DORZOLAMIDE HYDROCHLORIDE 22,26 mg TIMOLOL MALEATE 6,83 mg	Not listed	46027046/15.4/0270	Cancelled	Not determined	None
Glaumide-co EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	20 mg/ml + 5 mg/mlOphthalmic solution	46068446/15.4/0684Approved 11 October 2022	Registered	Not determined	PI PIL
Dorzolamide co eye drops pharma-q Each 1,0 ml contains 22,26 mg DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg 6,83 mg and TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Drops	48079648/15.4/0796	Registered	Not determined	None
Timdopt Each 1ml contains DORZOLAMIDE 20,0 mg TIMOLOL 5,0 mg	Not listed	50040250/15.4/0402	Registered	Not determined	None
Glautidor Each 1 ml solution contains DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg and TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	51006651/15.4/0066	Registered	Not determined	None
Ocudor co EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	51016251/15.4/0162	Registered	Not determined	None
Eyezolad EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	53017653/15.4/0176	Registered	Not determined	None
Dorzopt forte EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	20 mg, 5 mgEye drops solution	54025754/15.4/0257Approved 5 September 2023	Registered	S3	PI PIL
Dorzopres forte EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	20 mg, 5 mgEye drops solution	540258.25754/15.4/0258.257Approved 5 September 2023	Registered	S3	PI PIL
Micogloma co EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	56084356/15.4/0843	Registered	Not determined	None
Dorzolamide co adco EACH 1,0 ml SOLUTION CONTAINS DORZOLAMIDE HYDROCHLORIDE EQUIVALENT TO DORZOLAMIDE 20,0 mg TIMOLOL MALEATE EQUIVALENT TO TIMOLOL 5,0 mg	Not listed	560844.84356/15.4/0844.843	Registered	Not determined	None
Timozera Each 1,0 ml Solution contains: Dorzolamide hydrochloride equivalent to Dorzolamide 20,0 mg, Timolol Maleate equivalent to Timolol 5,0 mg	Not listed	561210.120956/15.4/1210.1209	Registered	Not determined	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, read from the product's PI-PIL leaflet.

The Consolidated Schedules list this ingredient up to S4; the leaflet's S3 applies to this product.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Dorzolamide hydrochloride equivalent to dorzolamide, timolol maleate equivalent to timolol

S4: Bimatoprost
Consolidated Schedules 06 July 2026, line 5499
S4: Latanoprost
Consolidated Schedules 06 July 2026, line 6878
S4: Travoprost
Consolidated Schedules 06 July 2026, line 8272
S3: Brinzolamide
Consolidated Schedules 06 July 2026, line 3235
S3: Dorzolamide
Consolidated Schedules 06 July 2026, line 3486
S3: Timolol
Consolidated Schedules 06 July 2026, line 4325

Pharmacological class: Others. (class 15.4)

Matched through the components Bimatoprost, Dorzolamide, Latanoprost, Brinzolamide, Travoprost.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Cosopt, Mundipharma (Pty) Ltd is scheduled S3 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsCosopt, Mundipharma (Pty) Ltd Patient information leaflet (PIL)For patients and carersCosopt, Mundipharma (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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