Donepezil
Sold as Aricept, Ariknow, Ran-donepezil, Donecept, Zelmeron, Arimentia, Arimer, Curlovon, Nelopt, Zepanalz, Prifet, Ensorin, Alzido, Donepezil zydus, Deptor, Jubezil, Nepizel, Donepezil unicorn, Donepezil SPEC, Donecept odt
2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Drag to rotate. Structure from PubChem CID 3152.
Background
Registration
- Applicants
- 15
- Registrations
- 40
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Pfizer Laboratories (Pty) Ltd | Aricept | 5 mg, 10 mg | 320315, 320316 | S5 | None |
| Ranbaxy Pharmaceutical (Pty) Ltd1 of 2 cancelled | Ariknow | 5, 10 | 410835, 410836 | S5 | None |
| MSQ Pharma (Pty) Ltd | Ran-donepezil, Arimer | 5, 10 | 410837, 410838, 430668, 430669 | S5 | None |
| Cipla Medpro (Pty) Ltd | Donecept, Donecept odt | 5, 10 | 420490, 420491, 530046, 530047 | S5 | None |
| Ascendis Pharma (Pty) LtdCancelled | Zelmeron | 5, 10 | 430435, 430436 | S5 | None |
| Pharmacare limited û woodmead | Arimentia | 5 mg, 10 mg | 430487, 430488 | S5 | None |
| Dr Reddyæs Laboratories (Pty) LtdCertificate held by Dr. Reddy’s Laboratories (Pty) Ltd. | Curlovon | 5 mg, 10 | 440933, 440934 | S5 | PI |
| Aurogen South Africa (Pty) Ltd2 of 6 cancelled | Nelopt, Zepanalz, Prifet | 5 mg, 10 mg | 440942, 440943, 440944, 440945, 440946, 440947 | S5 | None |
| Macleods Pharmaceuticals SA (Pty) Ltd | Ensorin | 5 mg, 10 mg | 450682, 450683 | S5 | None |
| Zydus Healthcare (Pty) Ltd | Alzido, Donepezil zydus | 5 mg, 10 mg | 450939, 450940, 450941, 450942 | S5 | None |
| Trinity Pharma (Pty) Ltd | Deptor | 5, 10 | 451029, 451030 | S5 | None |
| Jubilant Pharma SA (Pty) Ltd | Jubezil | 5, 10 | 451123, 451124 | S5 | None |
| Unichem SA (Pty) Ltd | Nepizel | 5, 10 | 460404, 460405 | S5 | None |
| Unicorn Pharmaceuticals (Pty) Ltd | Donepezil unicorn | 5, 10 | 460406, 460407 | S5 | PIPIL |
| Specpharm (Pty) Ltd | Donepezil SPEC | 5, 10 | 460634, 460635 | S5 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Aricept 5 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5 mg | 5 mg | 32031532/5.3/0315 | Registered | S5 | None |
| Aricept 10 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10 mg | 10 mg | 32031632/5.3/0316 | Registered | S5 | None |
| Ariknow 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 41083541/5.3/0835 | Cancelled | S5 | None |
| Ariknow 10 EACH TABLET CONTAINS: DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 41083641/5.3/0836 | Registered | S5 | None |
| Ran-donepezil 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 41083741/5.3/0837 | Registered | S5 | None |
| Ran-donepezil 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 41083841/5.3/0838 | Registered | S5 | None |
| Donecept 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE EQUIVALENT TO DONEPEZIL 5,0 mg | 5 | 42049042/5.3/0490 | Registered | S5 | None |
| Donecept 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE EQUIVALENT TO DONEPEZIL 10,0 mg | 10 | 42049142/5.3/0491 | Registered | S5 | None |
| Zelmeron 5 EACH TABLET CONTAINS: DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 43043543/5.3/0435 | Cancelled | S5 | None |
| Zelmeron 10 EACH TABLET CONTAINS: DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 43043643/5.3/0436 | Cancelled | S5 | None |
| Arimentia 5 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mg | 43048743/5.3/0487 | Registered | S5 | None |
| Arimentia 10 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mg | 43048843/5.3/0488 | Registered | S5 | None |
| Arimer 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 43066843/5.3/0668 | Registered | S5 | None |
| Arimer 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 43066943/5.3/0669 | Registered | S5 | None |
| Curlovon 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mgFilm-coated tablet | 44093344/5.3/0933Approved 18 February 2016 | Registered | S5 | PI |
| Curlovon 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 44093444/5.3/0934 | Registered | S5 | None |
| Nelopt 5 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mgTablets | 44094244/5.3/0942 | Cancelled | S5 | None |
| Nelopt 10 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mgTablets | 44094344/5.3/0943 | Cancelled | S5 | None |
| Zepanalz 5 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mgTablets | 44094444/5.3/0944 | Registered | S5 | None |
| Zepanalz 10 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mgTablets | 44094544/5.3/0945 | Registered | S5 | None |
| Prifet 5 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mgTablets | 44094644/5.3/0946 | Registered | S5 | None |
| Prifet 10 MG tablets EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mgTablets | 44094744/5.3/0947 | Registered | S5 | None |
| Ensorin 5 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mg | 45068245/5.3/0682 | Registered | S5 | None |
| Ensorin 10 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mg | 45068345/5.3/0683 | Registered | S5 | None |
| Alzido 5 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mg | 45093945/5.3/0939 | Registered | S5 | None |
| Alzido 10 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mg | 45094045/5.3/0940 | Registered | S5 | None |
| Donepezil zydus 5 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 mg | 45094145/5.3/0941 | Registered | S5 | None |
| Donepezil zydus 10 MG EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 mg | 45094245/5.3/0942 | Registered | S5 | None |
| Deptor 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 45102945/5.3/1029 | Registered | S5 | None |
| Deptor 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 45103045/5.3/1030 | Registered | S5 | None |
| Jubezil 5 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 45112345/5.3/1123 | Registered | S5 | None |
| Jubezil 10 EACH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 45112445/5.3/1124 | Registered | S5 | None |
| Nepizel 5 EACH TABLET CONTAINS : DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 46040446/5.3/0404 | Registered | S5 | None |
| Nepizel 10 EACH TABLET CONTAINS : DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 46040546/5.3/0405 | Registered | S5 | None |
| Donepezil unicorn 5 EACH TABLET CONTAINS : DONEPEZIL HYDROCHLORIDE 5,0 mg | 5Tablets | 46040646/5.3/0406Approved 24 April 2024 | Registered | S5 | PIPIL |
| Donepezil unicorn 10 EACH TABLET CONTAINS : DONEPEZIL HYDROCHLORIDE 10,0 mg | 10Tablets | 46040746/5.3/0407Approved 24 April 2024 | Registered | S5 | PIPIL |
| Donepezil 5 SPEC Each tablet contains DONEPEZIL HYDROCHLORIDE 5 mg EQUIVALENT TO DONEPEZIL FREE BASE 4,56 mg | 5 | 46063446/5.3/0634 | Registered | S5 | None |
| Donepezil 10 SPEC Each tablet contains DONEPEZIL HYDROCHLORIDE 10 mg EQUIVALENT TO DONEPEZIL FREE BASE 9,12 mg | 10 | 46063546/5.3/0635 | Registered | S5 | None |
| Donecept odt 5 ECAH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 5,0 mg | 5 | 53004653/5.3/0046 | Registered | S5 | None |
| Donecept odt 10 ECAH TABLET CONTAINS DONEPEZIL HYDROCHLORIDE 10,0 mg | 10 | 53004753/5.3/0047 | Registered | S5 | None |
Regulatory status
Where S5 sits on the scale
Prescription-only, with tighter controls on repeats.
Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S5, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.
Consolidated Schedules listings for Donepezil hydrochloride
S5: Donepezil
Consolidated Schedules 06 July 2026, line 9389
Pharmacological class: Cholinomimetics (cholinergics). (class 5.3)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Curlovon 5, Dr Reddyæs Laboratories (Pty) Ltd is scheduled S5 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.