Domperidone
Sold as Vomidon, Bio domperidone, Domperidone cipla, Motivom odt, Apex domperidone, Vomi-guard, Motilium
6-Chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Drag to rotate. Structure from PubChem CID 3151.
Background
Registration
- Applicants
- 7
- Registrations
- 9
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Ranbaxy (SA) (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) Ltd1 of 2 cancelled | Vomidon | 1 mg / 1 ml, 10 mg | 310330, 310331 | S4 | PIPIL |
| Biotech Laboratories (Pty) LtdCertificate held by Biotech Laboratories (Pty) Ltd. | Bio domperidone | 10 mg | 420836 | S4 | PIPIL |
| Cipla Medpro (Pty) Ltd | Domperidone cipla | Not stated | 520563 | S4 | None |
| Activo Health (Pty) Ltd | Motivom odt | 10 mg | 570158 | S4 | PIPIL |
| Austell Pharmaceuticals (Pty) Ltd | Apex domperidone, Vomi-guard | 10 mg -, 10 mg | A380620, A380636 | S4 | None |
| Johnson & Johnson (Pty) Ltd û Cape TownCertificate held by Johnson & Johnson (Pty) Ltd | Motilium | 10 mg | K0261 | S4 | PIPIL |
| Janssen Pharmaceutica (Pty) LtdCancelled | Motilium | 1 mg/ml | V0019 | S4 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Vomidon tablets EACH TABLET CONTAINS DOMPERIDONE 10,0 mg | 10 mgTablet. | 31033031/5.7.2/0330Approved 31 October 2022 | Registered | S4 | PIPIL |
| Vomidon suspension EACH 1,0 ml SUSPENSION CONTAINS DOMPERIDONE 1,0 mg | 1 mg / 1 mlSuspension | 31033131/5.7.2/0331Approved 30 September 2021 | Cancelled | S4 | PIPIL |
| Bio domperidone 10 EACH TABLET CONTAINS DOMPERIDONE 10,0 mg | 10 mgFilm-coated tablet | 42083642/5.7.2/0836Approved 28 September 2023 | Registered | S4 | PIPIL |
| Domperidone cipla Each tablet contains DOMPERIDONE 10,0 mg | Not listed | 52056352/5.7.2/0563 | Registered | S4 | None |
| Motivom 10 odt Each Tablet contains: Domperidone | 10 mgTablet | 57015857/5.7.2/0158Approved 3 June 2025 | Registered | S4 | PIPIL |
| Apex - domperidone 10 MG tablets EACH TABLET CONTAINS DOMPERIDONE MALEATE EQUIVALENT TO DOMPERIDONE 10,0 mg | 10 mg -Tablets | A380620A38/5.7.2/0620 | Registered | S4 | None |
| Vomi-guard 10 MG tablets EACH TABLET CONTAINS DOMPERIDONE 10,0 mg | 10 mgTablets | A380636A38/5.7.2/0636 | Registered | S4 | None |
| Motilium EACH TABLET CONTAINS DOMPERIDONE 10,0 mg | 10 mgFilm coated tablets. | K0261K/5.7.2/261Approved 12 May 2022 | Registered | S4 | PIPIL |
| Motilium 1 mg/ml EACH 1,0 ml SUSPENSION CONTAINS DOMPERIDONE 1,0 mg | 1 mg/ml | V0019V/5.7.2/19 | Cancelled | S4 | None |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Domperidone
S4: Domperidone
Consolidated Schedules 06 July 2026, line 6102
Pharmacological class: Anti-emetics and antivertigo preparations. (class 5.7.2)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.