Diltiazem

Sold as Adco-zildem sr, Zildem, Adco zildem, Dilem, Dilatam

C₂₂H₂₆N₂O₄S414.50 g/mol

[(2S,3S)-5-[2-(Dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate

Drag to rotate. Structure from PubChem CID 39186.

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Registration

Applicants: 3
Registrations: 8
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Adcock ingram limited	Adco-zildem sr, Zildem, Adco zildem	60, 90, 180, 240	300183, 300184, 300287, 300288	S3	PI PIL
Acino Pharma (Pty) LtdCancelled	Dilem	30 mg, 60 mg	370230, 370231	S3	None
Pharmacare limited û woodmead1 of 2 cancelled	Dilatam	30 mg, 60 mg	X0327, X0328	S3	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Adco-zildem 180 sr EACH CAPSULE CONTAINS DILTIAZEM HYDROCHLORIDE 180 mg	180	30018330/7.1/0183	Registered	S3	None
Adco-zildem 240 sr EACH CAPSULE CONTAINS DILTIAZEM HYDROCHLORIDE 240,0 mg	240	30018430/7.1/0184	Registered	S3	None
Zildem 60 TABLET DILTIAZEM HYDROCHLORIDE 60 MG	60	30028730/7.1/0287	Registered	S3	None
Adco zildem 90 EACH TABLET CONTAINS DILTIAZEM HYDROCHLORIDE 90 MG	90Sustained release capsule	30028830/7.1/0288Approved 5 July 2024	Registered	S3	PI PIL
Dilem 30 MG EACH TABLET CONTAINS DILTIAZEM HYDROCHLORIDE 30,0 mg	30 mg	37023037/7.1/0230	Cancelled	S3	None
Dilem 60 MG EACH TABLET CONTAINS DILTIAZEM HYDROCHLORIDE 60,0 mg	60 mg	37023137/7.1/0231	Cancelled	S3	None
Dilatam 30 MG EACH TABLET CONTAINS DILTIAZEM HYDROCHLORIDE 30 MG	30 mg	X0327X/7.1/0327	Cancelled	S3	None
Dilatam 60 MG EACH TABLET CONTAINS DILTIAZEM HYDROCHLORIDE 60 mg	60 mg	X0328X/7.1/0328	Registered	S3	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Diltiazem hydrochloride

S3: Diltiazem
Consolidated Schedules 06 July 2026, line 3470

Pharmacological class: Vasodilators, hypotensive, antihypertensive medicines include other antihypertensive medicines e.g. ACE-inhibitors, ARBs, RAAS, etc] (class 7.1)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsAdco zildem 90, Adcock ingram limited Patient information leaflet (PIL)For patients and carersAdco zildem 90, Adcock ingram limited

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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