Dienogest

Sold as Visanne, Endoact, Metrinelle, Solvetta, Visafem, Dienogest adco, Dienogest PHARMC, Dienterna, Nomysis, Dienogest DYNA

C₂₀H₂₅NO₂311.40 g/mol

2-[(8S,13S,14S,17R)-17-Hydroxy-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]acetonitrile

Drag to rotate. Structure from PubChem CID 68861.

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Registration

Applicants: 7
Registrations: 10
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Bayer (Pty) Ltd û IsandoCertificate held by Bayer (Pty) Ltd	Visanne	2mg	440159	S3	PI PIL
Cipla Medpro (Pty) LtdCertificate held by Actor Pharma (Pty) Ltd1	Endoact	2 mg	500082	S3	PIL
Pharma Dynamics (Pty) Ltd	Metrinelle, Dienogest DYNA	2 mg, 300 mg	510194, 560340	S3	PI PIL
Sandoz South Africa (Pty) LtdCancelled	Solvetta	Not stated	520185	S3	None
Adcock ingram limited1 of 2 cancelled	Visafem, Dienogest adco	2mg	550034, 550035.034	S3	PI PIL
Pharmacorp (Pty) Ltd	Dienogest PHARMC	2 mg	550725	S3	PI PIL
Trinity Pharma (Pty) Ltd	Dienterna, Nomysis	2 mg	550896, 550897.896	S3	PI PIL

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Visanne EACH TABLET CONTAINS DIENOGEST 2,0 mg	2mgTablet	44015944/21.8.2/0159Approved 1 March 2022	Registered	S3	PI PIL
Endoact Each tablet contains DIENOGEST 2,0 mg	2 mgTablets	50008250/21.8.2/0082Approved 14 December 2022	Registered	S3	PIL
Metrinelle Each tablet contains DIENOGEST 2,0 mg	2 mgTablets.	51019451/21.8.2/0194Approved 21 January 2025	Registered	S3	PI PIL
Solvetta Each tablet contains DIENOGEST 2,0 mg	Not listed	52018552/21.8.2/0185	Cancelled	S3	None
Visafem EACH TABLET CONTAINS DIENOGEST 2,0 mg	2mgTablet	55003455/18.8/0034Approved 28 February 2022	Cancelled	S3	PI PIL
Dienogest adco EACH TABLET CONTAINS DIENOGEST 2,0 mg	2mgTablet	550035.03455/18.8/0035.034Approved 28 February 2022	Registered	S3	PI PIL
Dienogest 2 MG PHARMC EACH TABLET CONTAINS DIENOGEST 2,0 mg	2 mgTablet	55072555/21.8.2/0725Approved 25 April 2023	Registered	S3	PI PIL
Dienterna 2 EACH TABLET CONTAINS DIENOGEST 2,0 mg	2 mgTablet	55089655/21.8.2/0896Approved 1 August 2023	Registrered	S3	PI PIL
Nomysis 2 EACH TABLET CONTAINS DIENOGEST 2,0 mg	2 mgTablet	550897.89655/21.8.2/0897.896Approved 1 August 2023	Registrered	S3	PI PIL
Dienogest 2 MG DYNA EACH TABLET CONTAINS DIENOGEST 2,0 mg	300 mgTablet	56034056/21.8.2/0340Approved 21 January 2025	Registered	S3	PI PIL

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Dienogest

S3: Dienogest
Consolidated Schedules 06 July 2026, line 3429

Pharmacological class: Progesterones with or without oestrogens. (class 21.8.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsVisanne, Bayer (Pty) Ltd û Isando Patient information leaflet (PIL)For patients and carersVisanne, Bayer (Pty) Ltd û Isando

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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