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Methylprednisolone (Depo-medrol, Medrol, Solu-medrol)

Methylprednisolone

Pfizer Laboratories (Pty) Ltd

S4

Registration

Applicant
Pfizer Laboratories (Pty) Ltd
Registrations
4
Schedule source
Consolidated Schedules 06 July 2026

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Depo-medrol 40 MG

EACH 1,0 ml SUSPENSION CONTAINS METHYLPREDNISOLONE ACETATE A 40,0 mg

40 mgC0726Old MedicineS4None
Medrol 16 MG

EACH TABLET CONTAINS METHYLPREDNISOLONE A 16,0 mg

16 mgC0728Old MedicineS4None
Solu-medrol 40 MG

EACH VIAL CONTAINS METHYLPREDNISOLONE SODIUM SUCCINATE EQUIVALENT TO 40 mg METHYLPREDNISOLONE

40 mgD0135D/21.5./135RegisteredS4None
Solu-medrol 125

EACH VIAL CONTAINS METHYLPREDNISOLONE SODIUM SUCCINATE EQUIVALENT TO 125 mg METHYLPREDNISOLONE

125D0136D/21.5.1/136RegisteredS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Methylprednisolone acetate

  • S4: Methylprednisolone

    Consolidated Schedules 06 July 2026, line 7098

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

C24H32O6416.50 g/mol

[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

Drag to rotate. Structure from PubChem CID 5877.

SAHPRA documents

SAHPRA has not published a professional information or patient information leaflet for this product.

Background

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Research articles

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