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Cyproterone

Sold as Androcur, Cyproplex, Cipla-cyproterone acetate, Androfem, Androcur depot

S4
Loading the molecular structure
C24H29ClO4416.90 g/mol

[(1S,2S,3S,5R,11R,12S,15R,16S)-15-Acetyl-9-chloro-2,16-dimethyl-6-oxo-15-pentacyclo[9.7.0.02,8.03,5.012,16]octadeca-7,9-dienyl] acetate

Drag to rotate. Structure from PubChem CID 9880.

Background

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Registration

Applicants
4
Registrations
8
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Pharmaco Distribution (Pty) LtdCertificate held by Bayer (Pty) LtdAndrocur, Androcur depot50 mg, 100 mg, 300 mg290515, R0160, R0184S4PIPIL
Teva Pharmaceuticals (Pty) LtdCancelledCyproplex50 mg350155S4None
Cipla Medpro (Pty) Ltd1 of 3 cancelledCipla-cyproterone acetate, Androfem50, 100350293, 360167, A390629S4None
Bayer (Pty) Ltd û IsandoCancelledAndrocur10 mgR0159S4None

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Androcur 100 MG

EACH TABLET CONTAINS CYPROTERONE ACETATE 100,0 mg

100 mg29051529/21.12/0515RegisteredS4None
Cyproplex 50 MG

EACH TABLET CONTAINS CYPROTERONE ACETATE 50,0 mg

50 mg35015535/21.12/0155CancelledS4None
Cipla-cyproterone acetate 50

EACH TABLET CONTAINS CYPROTERONE ACETATE 50,0 mg

5035029335/21.12/0293RegisteredS4None
Androfem

EACH TABLET CONTAINS CYPROTERONE ACETATE 50,0 mg

Not listed36016736/21.12/0167RegisteredS4None
Androfem 100

EACH TABLET CONTAINS CYPROTERONE ACETATE 100,0 mg

100A390629A39/21.12/0629CancelledS4None
Androcur 10 MG tablets

EACH TABLET CONTAINS CYPROTERONE ACETATE 10 mg

10 mgTabletsR0159R/21.12/159CancelledS4None
Androcur 50 MG tablets

EACH TABLET CONTAINS CYPROTERONE ACETATE 50 mg

50 mgTabletsR0160R/21.12/160RegisteredS4None
Androcur depot

EACH 3 ml OILY SOLUTION CONTAINS CYPROTERONE ACETATE 300 mg

300 mgSolution for injectionR0184R/21.12/184Approved 14 December 2021RegisteredS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Cyproterone acetate

  • S4: Cyproterone acetate

    Consolidated Schedules 06 July 2026, line 5916

Pharmacological class: Hormone inhibitors. (class 21.12)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Androcur depot, Pharmaco Distribution (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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