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Clofazimine

Sold as Tubramak, Leproculmin, Lamprene

S4Read from the PI-PIL document
Loading the molecular structure
C27H22Cl2N4473.40 g/mol

N,5-Bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine

Drag to rotate. Structure from PubChem CID 2794.

Background

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Registration

Applicants
3
Registrations
4
Schedule source
SAHPRA documentation

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Macleods Pharmaceuticals SA (Pty) LtdTubramak50 mg, 100 mg540238.236, 540239.237S4PIPIL
Equity Pharmaceutical (Pty) LtdLeproculminNot stated560529S4None
Ciba-geigy (Pty) LtdCertificate held by NovartisCancelledLamprene100A0108S4PIPIL

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Tubramak 50 MG

EACH TABLET CONTAINS CLOFAZIMINE 50,0 mg

50 mgTablet540238.23654/20.2.3/0238.236Approved 25 April 2023RegisteredS4PIPIL
Tubramak 100 MG

EACH TABLET CONTAINS CLOFAZIMINE 100,0 mg

100 mgTablet540239.23754/20.2.3/0239.237Approved 25 April 2023RegisteredS4PIPIL
Leproculmin

EACH CAPSULE CONTAINS CLOFAZIMINE 100,0 mg

Not listed56052956/20.0/0529RegisteredS4None
Lamprene 100

CAPSULE CLOFAZIMINE A 100 MG

100Gelatine capsulesA0108Approved 22 August 2024CancelledS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Clofazimine

  • S4: Clofazimine

    Consolidated Schedules 06 July 2026, line 5846

Pharmacological class: Tuberculostatics. (class 20.2.3)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Tubramak 50 MG, Macleods Pharmaceuticals SA (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 80% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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