Clobetasol propionate usp
Sold as Glencosol, Glencosol m/m foam, Clobetasol shalina, Maklovate, Clobder
(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Drag to rotate. Structure from PubChem CID 5311051.
Background
Registration
- Applicants
- 3
- Registrations
- 5
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Glenmark Pharmaceuticals South Africa (Pty) Ltd | Glencosol, Glencosol m/m foam | cream, 0,05% | 530397, 530556 | S4 | None |
| Phramadyne Healthcare (Pty) LtdCertificate held by Pharmadyne Healthcare (Pty) Ltd | Clobetasol shalina | 0,05 % w/v | 570041 | S4 | PIPIL |
| Macleods Pharmaceuticals SA (Pty) Ltd | Maklovate, Clobder | 500 μg | 580178, 580179.178 | S4 | PIPIL |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Glencosol cream EACH 1,0 g CREAM CONTAINS CLOBETASOL PROPIONATE USP 0,5 mg | Cream | 53039753/13.4.1/0397 | Registered | S4 | None |
| Glencosol 0,05% m/m foam EACH 1,0 g OF FOAM CONTAINS CLOBETASOL PROPIONATE USP 0,5 mg | 0,05% | 53055653/13.4.1/0556 | Registered | S4 | None |
| Clobetasol lotion shalina EACH BOTTLE CONTAINS: CLOBETASOL PROPIONATE USP 0,05 % w/v | 0,05 % w/vClear transparent liquid | 57004157/13.4.1/0041Approved 21 October 2025 | Registered | S4 | PIPIL |
| Maklovate 500 μg/g spray EACH 1,0 g SPRAY SOLUTION CONTAINS: CLOBETASOL PROPIONATE 500,0 μg | 500 μgTopical spray | 58017858/13.4.1/0178Approved 9 June 2026 | Registered | S4 | PIPIL |
| Clobder spray 500 μg/g EACH 1,0 g SPRAY SOLUTION CONTAINS: CLOBETASOL PROPIONATE 500,0 μg | 500 μgTopical spray | 580179.17858/13.4.1/0179.178Approved 9 June 2026 | Registered | S4 | PIPIL |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, matched to the Consolidated Schedules by ingredient, confidence medium.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Clobetasol propionate usp
S4: Clobetasol
Consolidated Schedules 06 July 2026, line 5842
Pharmacological class: Corticosteroids with or without anti-infective agents. (class 13.4.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.