Clobetasol propionate

Sold as Dovate, Xenovate, Clobex, Glencosol m/m, Glencosol foam, Glencosol, Glencosol shampoo, Clonetastra, Clobetasol shalina, Clobex shampoo, Dermovate, Dermovate scalp application

S4Read from the PI-PIL document and verified

C₂₅H₃₂ClFO₅467.00 g/mol

[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

Drag to rotate. Structure from PubChem CID 32798.

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Registration

Applicants: 6
Registrations: 15
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pharmacare limited û woodmeadCertificate held by Pharmacare limited	Dovate, Xenovate	2,5 mg/5,0 g, 2,5 mg/ 5 g, ointment, cream	270122, 270316, 280611, 280728	S4	PI PIL
Galderma Laboratories S.A. (Pty) LtdCertificate held by Galderma Laboratories South Africa (Pty) Ltd1 of 2 cancelled	Clobex, Clobex shampoo	spray, 0.5 mg/g	460556, A400035	S4	PI PIL
Glenmark Pharmaceuticals South Africa (Pty) Ltd	Glencosol m/m, Glencosol foam, Glencosol, Glencosol shampoo	0,05%, emulsion, spray, 0,5 mg	530398, 530555, 530557, 550073	S4	PI PIL
Astral Pharma (Pty) Ltd	Clonetastra	Not stated	560417	S4	None
Pharmadyne Healthcare (Pty) Ltd	Clobetasol shalina	0,05 % w/v	570040	S4	PI PIL
Sekpharma (Pty) Ltd	Dermovate, Dermovate scalp application	ointment, cream	F0175, F0176, H0268	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Dovate ointment EACH 5 g OINTMENT CONTAINS CLOBETASOL PROPIONATE 2,5 mg	2,5 mg/5,0 gOintment	27012227/13.4.1/0122Approved 13 November 2023	Registered	S4	PI PIL
Dovate cream EACH 5 G CREAM CONTAINS CLOBETASOL PROPIONATE 2,5 MG	2,5 mg/ 5 gCream	27031627/13.4.1/0316Approved 13 November 2023	Registered	S4	PI PIL
Xenovate ointment EACH 5 g OINTMENT CONTAINS CLOBETASOL PROPIONATE 0,0025 g	Ointment	28061128/13.4.1/0611	Registered	S4	None
Xenovate cream EACH 5 g CREAM CONTAINS CLOBETASOL PROPIONATE 0,0025 g	Cream	28072828/13.4.1/0728	Registered	S4	None
Clobex spray EACH 1,0 g SOLUTION CONTAINS CLOBETASOL PROPIONATE 500,0 ug	Spray	46055646/13.4.1/0556	Cancelled	S4	None
Glencosol 0,05% m/m ointment EACH 1,0 g OF OINTMENT CONTAINS CLOBETASOL PROPIONATE 0,5 mg	0,05%Ointment	53039853/13.4.1/0398	Registered	S4	None
Glencosol emulsion foam EACH 1,0 mg FOAM CONTAINS CLOBETASOL PROPIONATE 0,5 mg	Emulsion	53055553/13.4.1/0555	Registered	S4	None
Glencosol spray EACH 1,0 g SPRAY SOLUTION CONTAINS CLOBETASOL PROPIONATE 500,0 µg	Spray	53055753/13.4.1/0557	Registered	S4	None
Glencosol shampoo	0,5 mgLiquid	55007355/13.4.1/0073Approved 28 June 2022	Registered	S4	PI PIL
Clonetastra EACH 1,0 mg SHAMPOO CONTAINS CLOBETASOL PROPIONATE 0,5 mg	Not listed	56041756/13.4.1/0417	Registered	S4	None
Clobetasol cream shalina EACH 1,0 g CREAM CONTAINS CLOBETASOL PRO	0,05 % w/vCream	57004057/13.4.1/0040Approved 25 March 2025	Registered	S4	PI PIL
Clobex shampoo EACH 1,0 g CREAM CONTAINS CLOBETASOL PROPIONATE 0,5 mg	0.5 mg/gShampoo	A400035A40/13.4.1/0035Approved 12 May 2022	Registered	S4	PI PIL
Dermovate ointment EACH 100 g OINTMENT CONTAINS CLOBETASOL PROPIONATE 0,05 g	Ointment	F0175F/13.4.1/175	Registered	S4	None
Dermovate cream EACH 100 g OINTMENT CONTAINS CLOBETASOL PROPIONATE 0,05 g	Cream	F0176F/13.4.1/176	Registered	S4	None
Dermovate scalp application EACH 100 g LOTION CONTAINS CLOBETASOL PROPIONATE 0.05 g	Not listed	H0268H/13.4.1/268	Registered	S4	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Clobetasol propionate

S4: Clobetasol
Consolidated Schedules 06 July 2026, line 5842

Pharmacological class: Corticosteroids with or without anti-infective agents. (class 13.4.1)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Dovate ointment, Pharmacare limited û woodmead is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsDovate ointment, Pharmacare limited û woodmead Patient information leaflet (PIL)For patients and carersDovate ointment, Pharmacare limited û woodmead

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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