Chlorpromazine
Sold as Chlorpromazine unimed, Largactil, Klorazin, Chlorpromaject, Chlorpromazine, Chlorpromazine- fresenius, Chlorpromazine fresenius, Repazine, Chlorpromazine (lennon)
3-(2-Chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
Drag to rotate. Structure from PubChem CID 2726.
Background
Registration
- Applicants
- 8
- Registrations
- 23
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Unimed Healthcare (Pty) Ltd | Chlorpromazine unimed | 25, 50 | 270463, 270464 | S5 | None |
| Sanofi-aventis South Africa (Pty) Ltd | Largactil | 10, 50 | B0510, B0512 | S5 | PIPIL |
| Biotech Laboratories (Pty) LtdCertificate held by Sanofi-aventis South Africa (Pty) Ltd | Largactil | 25, 100 | B0511, B0513 | S5 | PIPIL |
| The Premier Pharmaceutical Co LtdCancelled | Klorazin, Chlorpromazine | 10 MG, 25 MG, 50 MG, 100 MG, elixir | B0824, B0825, B0827, B0828, B1214, B1217, B1218, B1219 | S5 | None |
| Vernleigh Pharmaceuticals (Pty) LtdCancelled | Klorazin | 25MG/ML | B0826 | S5 | None |
| Genpharm Pharmaceuticals (1993) (Pty) Ltd | Chlorpromaject | 25 MG, 50 MG | B0879, B1642 | S5 | None |
| Fresenius Medical Care South Africa (Pty) Ltd | Chlorpromazine- fresenius, Chlorpromazine fresenius | 25 mg/1 ml, 50 mg/2 ml | B1449, B1636 | S5 | None |
| Pharmacare limited û woodmeadCancelled | Repazine, Chlorpromazine (lennon) | 25 mg, 50 mg, 100 mg | L0391, L0392, L0393, M0185 | S5 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Chlorpromazine 25 unimed EACH 1 ml SOLUTION CONTAINS CHLORPROMAZINE HYDROCHLORIDE 25 mg | 25 | 27046327/2.6.1/0463 | Registered | S5 | None |
| Chlorpromazine 50 unimed EACH 1 ml SOLUTION CONTAINS CHLORPROMAZINE HYDROCHLORIDE 50 mg | 50 | 27046427/2.6.1/0464 | Registered | S5 | None |
| Largactil 10 EACH TABLET CONTAINS :CHLORPROMAZINE A 10 mg | 10Tablets. | B0510Approved 14 October 2022 | Old Medicine | S5 | PIPIL |
| Largactil 25 EACH TABLET CONTAINS CHLORPROMAZINE HYDROCHLORIDE A 25 mg | 25Tablets. | B0511Approved 14 October 2022 | Old Medicine | S5 | PIPIL |
| Largactil 50 EACH TABLET CONTAINS CHLORPROMAZINE A 50 mg | 50Tablets. | B0512Approved 14 October 2022 | Old Medicine | S5 | PIPIL |
| Largactil 100 EACH TABLET CONTAINS CHLORPROMAZINE A 100 mg | 100Tablets. | B0513Approved 14 October 2022 | Old Medicine | S5 | PIPIL |
| Klorazin 25 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 25 MG | 25 MG | B0824 | Cancelled | S5 | None |
| Klorazin 50 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 50 MG | 50 MG | B0825 | Cancelled | S5 | None |
| Klorazin 25mg/ml 1 ML CHLORPROMAZINE HYDROCHLORIDE A 25 MG | 25MG/ML | B0826 | Cancelled | S5 | None |
| Klorazin 100 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 100 MG | 100 MG | B0827 | Cancelled | S5 | None |
| Klorazin 10 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 10 MG | 10 MG | B0828 | Cancelled | S5 | None |
| Chlorpromaject 25 MG 1 ML CHLORPROMAZINE HYDROCHLORIDE A 25 MG | 25 MG | B0879 | Old Medicine | S5 | None |
| Chlorpromazine elixir 5 ML CHLORPROMAZINE HYDROCHLORIDE A 25 MG | Elixir | B1214 | Cancelled | S5 | None |
| Chlorpromazine 50 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 51 MG | 50 MG | B1217 | Cancelled | S5 | None |
| Chlorpromazine 25 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 25,5 MG | 25 MG | B1218 | Cancelled | S5 | None |
| Chlorpromazine 10 MG TABLET CHLORPROMAZINE HYDROCHLORIDE A 10,2 MG | 10 MG | B1219 | Cancelled | S5 | None |
| Chlorpromazine- fresenius 25 mg/1 ML EACH 1,0 solution ml CONTAINS CHLORPROMAZINE HYDROCHLORIDE A 25,0 mg | 25 mg/1 ml | B1449 | Old Medicine | S5 | None |
| Chlorpromazine fresenius 50 mg/2 ML EACH 1,0 ml SOLUTION CONTAINS CHLORPROMAZINE HYDROCHLORIDE A 25,0 mg | 50 mg/2 ml | B1636 | Old Medicine | S5 | None |
| Chlorpromaject 50 MG 2 ML CHLORPROMAZINE HYDROCHLORIDE A 50 MG | 50 MG | B1642 | Old Medicine | S5 | None |
| Repazine 25 MG EACH TABLET CONTAINS CHLORPROMAZINE HYDROCHLORIDE 25 mg | 25 mg | L0391L/2.6.1/391 | Cancelled | S5 | None |
| Repazine 50 MG EACH TABLET CONTAINS CHLORPROMAZINE HYDROCHLORIDE 50 mg | 50 mg | L0392L/2.6.1/392 | Cancelled | S5 | None |
| Repazine 100 MG EACH TABLET CONTAINS CHLORPROMAZINE HYDROCHLORIDE 100 mg | 100 mg | L0393L/2.6.1/393 | Cancelled | S5 | None |
| Chlorpromazine (lennon) EACH SUPPOSITORY CONTAINS CHLORPROMAZINE HYDROCHLORIDE EQUIVALENT TO 100 mg CHLORPROMAZINE | Not listed | M0185M/2.6.1/185 | Cancelled | S5 | None |
Regulatory status
Where S5 sits on the scale
Prescription-only, with tighter controls on repeats.
Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S5, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.
Consolidated Schedules listings for Chlorpromazine hydrochloride
S5: Chlorpromazine
Consolidated Schedules 06 July 2026, line 9321
Pharmacological class: Phenothiazines and their derivatives. (class 2.6.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Largactil 10, Sanofi-aventis South Africa (Pty) Ltd is scheduled S5 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.