Cefazolin
Sold as Cefazolin fresenius, Ranzol, Litha cefazolin, Aspen cefazolin, Cefazolin oethmaan, Schein cefazolin, Adco cefazolin, Zefkol, Dezefcin, Mylan cefazolin, Spec-ziplen, Sratop, Auro-cefazolin, Rezolin, Cefazolin-fresenius
(6R,7R)-3-[(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Drag to rotate. Structure from PubChem CID 33255.
Background
Registration
- Applicants
- 11
- Registrations
- 27
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Fresenius Kabi South Africa (Pty) Ltd | Cefazolin fresenius, Cefazolin-fresenius | 1 g, 500 mg | 300076, Y0390 | S4 | None |
| Ranbaxy Pharmaceutical (Pty) Ltd1 of 2 cancelled | Ranzol | 1 g, 500 | 300332, 300333 | S4 | None |
| Acino Pharma (Pty) Ltd2 of 4 cancelled | Litha cefazolin, Aspen cefazolin, Zefkol | 0,5 g, 1,0 g, 500, 1000 | 310352, 310353, 370136, 370137 | S4 | None |
| Oethmaan Biosims (Pty) Ltd | Cefazolin oethmaan | 1 g, 500 mg | 310675, 310676 | S4 | None |
| Triomed (Pty) LtdCancelled | Schein cefazolin | 1 G, 500 mg | 330529, 330530 | S4 | None |
| Adcock Ingram Critical Care (Pty) Ltd | Adco cefazolin | 1 g, 500 mg | 360259, 360260 | S4 | None |
| Dezzo Trading 392 (Pty) Ltd | Dezefcin | 0,5 g, 1,0 g | 370382, 370383 | S4 | None |
| Biotech Laboratories (Pty) Ltd | Mylan cefazolin | 1 g | 410039 | S4 | None |
| Cospharm Investments (Pty) Ltd | Spec-ziplen | 1 g, 500 mg | 410317, 410318 | S4 | None |
| Aurogen South Africa (Pty) Ltd | Sratop, Auro-cefazolin | 1 g, 250 mg, 500 mg | 430637, 430638, 430639, 430640, 430641, 430642 | S4 | None |
| Resmed healthcare | Rezolin | 500, 1000 | A390113, A390114 | S4 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Cefazolin fresenius 1 g EACH 10 ml VIAL CONTAINS : CEFAZOLIN SODIUM EQUIVALENT TO 1 g CEFAZOLIN | 1 g | 30007630/20.1.1/0076 | Registered | S4 | None |
| Ranzol 500 injection EACH VIAL CONTAINS: CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500Injection | 30033230/20.1.1/0332 | Registered | S4 | None |
| Ranzol 1 g injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO 1 g CEFAZOLIN | 1 gInjection | 30033330/20.1.1/0333 | Cancelled | S4 | None |
| Litha cefazolin 500 injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500Injection | 31035231/20.1.1/0352 | Cancelled | S4 | None |
| Aspen cefazolin 1000 EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1000,0 mg | 1000 | 31035331/20.1.1/0353 | Cancelled | S4 | None |
| Cefazolin 500 MG oethmaan EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 31067531/20.1.1/0675 | Registered | S4 | None |
| Cefazolin 1 g oethmaan EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1 000,0 mg | 1 g | 31067631/20.1.1/0676 | Registered | S4 | None |
| Schein cefazolin 500 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 33052933/20.1.1/0529 | Cancelled | S4 | None |
| Schein cefazolin 1 g EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1,0 g | 1 G | 33053033/20.1.1/0530 | Cancelled | S4 | None |
| Adco cefazolin 500 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 36025936/20.1.1/0259 | Registered | S4 | None |
| Adco cefazolin 1 g EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1000,0 mg | 1 g | 36026036/20.1.1/0260 | Registered | S4 | None |
| Zefkol 0,5 g injection EACH VIAL CONTAINS :CEFAZOLIN SODIUM, STERILE EQUIVALENT TO CEFAZOLIN 0,5 g | 0,5 gInjection | 37013637/20.1.1/0136 | Registered | S4 | None |
| Zefkol 1,0 g injection EACH VIAL CONTAINS :CEFAZOLIN SODIUM, STERILE EQUIVALENT TO CEFAZOLIN 1,0 g | 1,0 gInjection | 37013737/20.1.1/0137 | Registered | S4 | None |
| Dezefcin 0,5 g injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 0,5 g | 0,5 gInjection | 37038237/20.1.1/0382 | Registered | S4 | None |
| Dezefcin 1,0 g injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1,0 g | 1,0 gInjection | 37038337/20.1.1/0383 | Registered | S4 | None |
| Mylan cefazolin 1 g EACH VIAL CONTAINS;CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1,0 g | 1 g | 41003941/20.1.1/0039 | Registered | S4 | None |
| Spec-ziplen 500 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 41031741/20.1.1/0317 | Registered | S4 | None |
| Spec-ziplen 1 g EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1000,0 mg | 1 g | 41031841/20.1.1/0318 | Registered | S4 | None |
| Sratop 250 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 250,0 mg | 250 mg | 43063743/20.1.1/0637 | Registered | S4 | None |
| Sratop 500 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 43063843/20.1.1/0638 | Registered | S4 | None |
| Sratop 1 g EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1,0 g | 1 g | 43063943/20.1.1/0639 | Registered | S4 | None |
| Auro-cefazolin 250 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 250,0 mg | 250 mg | 43064043/20.1.1/0640 | Registered | S4 | None |
| Auro-cefazolin 500 MG EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500 mg | 43064143/20.1.1/0641 | Registered | S4 | None |
| Auro-cefazolin 1 g EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1,0 g | 1 g | 43064243/20.1.1/0642 | Registered | S4 | None |
| Rezolin 500 injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 500,0 mg | 500Injection | A390113A39/20.1.1/0113 | Registered | S4 | None |
| Rezolin 1000 injection EACH VIAL CONTAINS CEFAZOLIN SODIUM EQUIVALENT TO CEFAZOLIN 1000,0 mg | 1000Injection | A390114A39/20.1.1/0114 | Registered | S4 | None |
| Cefazolin-fresenius 500 MG EACH 10 ml VIAL CONTAINS CEFAZOLIN SODIUM, STERILE EQUIVALENT TO 500 mg CEFAZOLIN | 500 mg | Y0390Y/20.1.1/390 | Registered | S4 | None |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Cefazolin sodium equivalent to cefazolin
S4: Cefazolin
Consolidated Schedules 06 July 2026, line 5703
Pharmacological class: Broad and medium spectrum antibiotics. (class 20.1.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
SAHPRA has not published a professional information or patient information leaflet for this product.