Carbidopa, levodopa
Sold as Carbilev, Carbi-levo teva, Duodopa, Lecardop, Sinemet, Sinemet cr
Combination product
This product contains more than one active ingredient, so it has no single molecular structure.
Background
Registration
- Applicants
- 5
- Registrations
- 10
- Schedule source
- SAHPRA documentation
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Pharmacare limited û woodmeadCertificate held by Pharmacare Ltd | Carbilev | 25/250, 25/100 | 300269, 300271 | S4 | PIPIL |
| Teva Pharmaceuticals (Pty) Ltd | Carbi-levo teva | 25/250, 25/100 | 320024, 320081 | S4 | None |
| Abbvie (Pty) LtdCancelled | Duodopa | Not stated | 440456 | S4 | None |
| Ranbaxy Pharmaceutical (Pty) Ltd | Lecardop | 25/250, 25/100 | 450764, 450765 | S4 | None |
| Organon South Africa (Pty) Ltd | Sinemet, Sinemet cr | 25/250, 25/100 | F0056, P0141, Y0279 | S4 | None |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Carbilev 25/250 EACH TABLET CONTAINS CARBIDOPA MONOHYDRATE EQUIVALENT TO 25 MG CARBIDOPA LEVODOPA 250 MG | 25/250Tablets. | 30026930/5.4.1/0269Approved 24 December 2020 | Registered | S4 | PIPIL |
| Carbilev 25/100 EACH TABLET CONTAINS CARBIDOPA MONOHYDRATE EQUIVALENT TO 25 MG CARBIDOPA LEVODOPA 100 MG | 25/100Tablets. | 30027130/5.4.1/0271Approved 24 December 2020 | Registered | S4 | PIPIL |
| Carbi-levo 25/250 teva EACH TABLET CONTAINS CARBIDOPA 25,0 mg LEVODOPA 250,0 mg | 25/250 | 32002432/5.4.1/0024 | Registered | S4 | None |
| Carbi-levo 25/100 teva EACH TABLET CONTAINS CARBIDOPA 25,00 mg LEVODOPA 100,0 mg | 25/100 | 32008132/5.4.1/0081 | Registered | S4 | None |
| Duodopa EACH 1,0 ml GEL CONTAINS CARBIDOPA 5,0 mg LEVODOPA 20,0 mg | Not listed | 44045644/5.4.1/0456 | Cancelled | S4 | None |
| Lecardop 25/250 EACH TABLET CONTAINS: CARBIDOPA 25,0 mg, LEVODOPA 250,0 mg | 25/250 | 45076445/5.4.1/0764 | Registered | S4 | None |
| Lecardop 25/100 EACH TABLET CONTAINS: CARBIDOPA 25,0 mg ,LEVODOPA 100,0 mg | 25/100 | 45076545/5.4.1/0765 | Registered | S4 | None |
| Sinemet 25/250 EACH TABLET CONTAINS CARBIDOPA 25 mg LEVODOPA 250 mg | 25/250 | F0056F/5.4.1/56 | Registered | S4 | None |
| Sinemet 25/100 EACH TABLET CONTAINS CARBIDOPA EQUIVALENT TO ANHYDROUS CARBIDOPA 25 mg LEVODOPA 100 mg | 25/100 | P0141P/5.4.1/141 | Registered | S4 | None |
| Sinemet cr EACH TABLET CONTAINS CARBIDOPA MONOHYDRATE EQUIVALENT TO 50 mg CARBIDOPA LEVODOPA 200 mg | Not listed | Y0279Y/5.4.1/279 | Registered | S4 | None |
Regulatory status
Where S4 sits on the scale
Prescription-only medicine.
Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S4, read from the product's PI-PIL leaflet.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Carbidopa monohydrate equivalent to carbidopa, levodopa
S4: Carbidopa
Consolidated Schedules 06 July 2026, line 5661
S4: Levodopa
Consolidated Schedules 06 July 2026, line 6907
Pharmacological class: Anti-Parkinsonism preparations. (class 5.4.1)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
Schedule Verification
Carbilev 25/250, Pharmacare limited û woodmead is scheduled S4 in its official SAHPRA documents, read with 90% confidence.
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.