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Bupivacaine (Bupivacaine Hcl Spinal With Dextrose Adco, Macaine Viaflex, Bupivacaine Viaflex Adco, Macaine Hcl, Macaine Hcl Spinal, * Adcane)

Bupivacaine

Adcock Ingram Critical Care (Pty) Ltd

S4Read from the PI-PIL document and verified

Registration

Applicant
Adcock Ingram Critical Care (Pty) Ltd
Certificate holder
Adcock Ingram Critical Care (Pty) Ltd.
Registrations
6
Schedule source
SAHPRA documentation

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Bupivacaine HCL 0,5 % spinal injection with dextrose adco

EACH 4,0 ML CONTAINS: BUPIVACAINE HYDROCHLORIDE 20,0 mg

5 mg/mLSpinal injection51054751/4/0547Approved 29 September 2025RegisteredS4PIPIL
Macaine viaflex 0,1 %

EACH 1000,0 ml SOLUTION CONTAINS BUPIVACAINE HYDROCHLORIDE 1,0 g

0,1 %A400182A40/4/0182RegisteredNot determinedNone
Bupivacaine 0,1 % viaflex adco

EACH 1000,0 ml SOLUTION CONTAINS :BUPIVACAINE HYDROCHLORIDE 1,0 g

0,1 %A400214A40/4/0214RegisteredNot determinedNone
Macaine HCL 0,5 % injection

EACH 1 ml SOLUTION CONTAINS: BUPIVACAINE HYDROCHLORIDE 5 mg

1 mLInjectionJ0113J/4/113Approved 27 October 2025RegisteredS4PIPIL
Macaine HCL 0,5 % spinal injection

EACH 1 ml SOLUTION CONTAINS :BUPIVACAINE HYDROCHLORIDE 5 mg

0,5 %InjectionU0055U/4/55RegisteredNot determinedNone
* adcane

EACH 10 ml SULUTION CONTAINS: BUPIVACAINE HYDROCHLORIDE 10 mg

Not listedZ0063Z/4/63RegisteredNot determinedNone

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

C18H28N2O288.40 g/mol

1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide

Drag to rotate. Structure from PubChem CID 2474.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

This medication's schedule (S4) has been verified from official SAHPRA documents with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Background

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Research articles

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