Brimonidine
Sold as Brimoct eye, Simbrinza, Agobrim w/v eye, Alphagan purite
5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine
Drag to rotate. Structure from PubChem CID 2435.
Background
Registration
- Applicants
- 4
- Registrations
- 4
- Schedule source
- Consolidated Schedules 06 July 2026
Applicants and registrations
| Applicant | Brands | Dosages | Registrations | Schedule | Leaflets |
|---|---|---|---|---|---|
| Gen-eye (Pty) Ltd | Brimoct eye | drops | 450688 | S3 | None |
| Novartis South Africa (Pty) LtdCertificate held by Novartis South Africa (Pty) Ltd. | Simbrinza | 10 mg/mL + 2 mg/mL | 500358 | S3 | PIPIL |
| FDC SA (Pty) Ltd | Agobrim w/v eye | 0.15% w/v | 570378 | S3 | PIPIL |
| Abbvie (Pty) Ltd | Alphagan purite | 1,5 mg/ml, | A390202 | S3 | PIPIL |
Variants
| Product | Strength and form | Registration | Status | Schedule | Leaflets |
|---|---|---|---|---|---|
| Brimoct eye drops EACH ml CONTAINS BRIMONIDINE TARTRATE 2,0 mg | Drops | 45068845/15.4/0688 | Registered | S3 | None |
| Simbrinza | 10 mg/mL + 2 mg/mLEye drops, suspension | 50035850/15.4/0358Approved 6 February 2023 | Registered | S3 | PIPIL |
| Agobrim 0,15 % w/v eye drops Each Vial contains: Brimonidine Tartrate 0,15 % w/v | 0.15% w/vEye drops | 57037857/15.4/0378Approved 15 July 2025 | Registered | S3 | PIPIL |
| Alphagan purite EACH 1,0 ml SOLUTION CONTAINS :BRIMONIDINE TARTRATE 1,5 mg | 1,5 mg/ml,Ophthalmic solution | A390202A39/15.4/0202Approved 21 April 2023 | Registered | S3 | PIPIL |
Regulatory status
Where S3 sits on the scale
Needs a doctor's prescription, dispensed by a pharmacist.
Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.
Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.
Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.
Consolidated Schedules listings for Brimonidine tartrate
S3: Brimonidine
Consolidated Schedules 06 July 2026, line 3233
Pharmacological class: Others. (class 15.4)
This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.
SAHPRA documents
These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.