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Formoterol (Breztri Aerosphere)

Formoterol

Astrazeneca Pharmaceuticals (Pty) Ltd

S4Read from the PI-PIL document and verified

Registration

Applicant
Astrazeneca Pharmaceuticals (Pty) Ltd
Certificate holder
Astrazeneca Pharmaceuticals (Pty) Ltd
Registrations
1
Schedule source
SAHPRA documentation

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Breztri aerosphere

EACH DELIVERED DOSE CONTAINS: BUDESONIDE 160,0 μg GLYCOPYRRONIUM BROMIDE EQUIVALENT TO GLYCOPYRRONIUM 7,2 μg FORMOTEROL FUMARATE DIHYDRATE EQUIVALENT TO FORMOTEROL FUMARATE 4,8 μg

160 microgramsPressurised inhalation, suspension59037559/10.3/0375Approved 21 October 2025RegisteredS4PIPIL

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Budesonide, glycopyrronium bromide equivalent to glycopyrronium, formoterol fumarate dihydrate equivalent to formoterol fumarate

  • S4: Budesonide

    • except when intended for the prophylaxis and treatment of seasonal and perennial allergic rhinitis in adults and children aged 12 years and older; (S2)
    • except when intended for inhalation or nasal administration, unless listed in another Schedule. (S3)

    Consolidated Schedules 06 July 2026, lines 5577 to 5582

  • S4: Formoterol

    Consolidated Schedules 06 July 2026, line 6443

  • S3: Budesonide

    • when intended inhalation or nasal administration, unless listed in another Schedule. (S4)
    • except when intended for the prophylaxis and treatment of seasonal and perennial allergic rhinitis in adults and children aged 12 years and older. (S2)

    Consolidated Schedules 06 July 2026, lines 3237 to 3242

  • S3: Glycopyrronium

    Consolidated Schedules 06 July 2026, line 3691

  • S2: Budesonide

    • when intended for the prophylaxis and treatment of seasonal and perennial allergic rhinitis in adults and children aged 12 years and older; (S3)
    • except when intended for inhalation and nasal administration, unless listed in another Schedule. (S4)

    Consolidated Schedules 06 July 2026, lines 1696 to 1701

Pharmacological class: Others. (class 10.3)

Matched through the components Budesonide, Glycopyrronium.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

C19H24N2O4344.40 g/mol

N-[2-Hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide

Drag to rotate. Structure from PubChem CID 3410.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

This medication's schedule (S4) has been verified from official SAHPRA documents with 90% confidence.

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Background

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Research articles

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