Bisoprolol

Sold as Cardicor, Cordicor, Adco bisocor, Adco-bisocor, Bisohexal, Bisoprolol unicorn, Bilocor, Betacor, Bisoprolol biotech, Ziapro, Bisozyd, Prosib, Bislo, Mylan bisoprolol, Bisbeta, Bisoprolol unimed, Retocar, Pentocor, Presese, Bisoprolol kiara, Bisoprolol accord, Presicard, Emcor, Rupro, Concor

C₁₈H₃₁NO₄325.40 g/mol

1-(Propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol

Drag to rotate. Structure from PubChem CID 2405.

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Registration

Applicants: 15
Registrations: 49
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Merck (Pty) Ltd	Cardicor, Cordicor, Betacor, Emcor, Concor	2,5 mg, 5, 10 mg	360457, 360458, 360459, 380080, 380081, 511021, 511023, V0303, V0304	S3	PI PIL
Adcock ingram limited	Adco bisocor, Adco-bisocor	5 mg, 10 mg	370010, 370011	S3	None
Sandoz South Africa (Pty) Ltd	Bisohexal	5, 10	370516, 370517	S3	None
Unicorn Pharmaceuticals (Pty) Ltd	Bisoprolol unicorn	5, 10	380050, 380052	S3	PI PIL
Pharma Dynamics (Pty) Ltd	Bilocor	5, 10	380051, 380053	S3	PI PIL
Biotech Laboratories (Pty) Ltd	Bisoprolol biotech	5, 10	380105, 380106	S3	None
Pharmacare limited û woodmeadCancelled	Ziapro	5 mg, 10 mg	410720, 410739	S3	None
Zydus Healthcare (Pty) Ltd	Bisozyd	5, 10	420847, 420848	S3	None
Ascendis Pharma (Pty) Ltd	Prosib	5, 10	450071, 450072	S3	None
Unichem SA (Pty) Ltd	Bislo, Bisoprolol kiara	5, 10	450128, 450129, 460390, 460391	S3	None
Viatris Healthcare (Pty) Ltd	Mylan bisoprolol	5 mg, 10 mg	450525, 450526	S3	None
Aurogen South Africa (Pty) Ltd	Bisbeta, Pentocor, Presese	2,5 mg, 5 mg, 10 mg	450789, 450790, 450791, 450864, 450865, 450866, 450867	S3	None
Unimed Healthcare (Pty) Ltd	Bisoprolol unimed, Retocar	2,5, 5, 10 mg	450792, 450793, 450794	S3	None
Accord Healthcare (Pty) Ltd	Bisoprolol accord, Presicard	2,5, 5, 10	470148, 470149, 470150, 470151, 470152, 470153	S3	None
Lebasi Pharmaceuticals (Pty) Ltd	Rupro	5, 10	570337, 570338	S3	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Cardicor 2,5 EACH TABLET CONTAINS: BISOPROLOL FUMARATE 2,5 mg	2,5	36045736/6.1/0457	Registered	S3	None
Cordicor 5 EACH TABLET CONTAINS: BISOPROLOL FUMARATE 5,0 mg	5	36045836/6.1/0458	Registered	S3	None
Cardicor 10 EACH TABLET CONTAINS: BISOPROLOL FUMARATE 10,0 mg	10	36045936/6.1/0459	Registered	S3	None
Adco bisocor 5 MG EACH TABLET CONTAINS BISOPROLOL 5,0 mg	5 mg	37001037/5.2/0010	Registered	S3	None
Adco-bisocor 10 MG EACH TABLET CONTAINS BISOPROLOL 10,0 mg	10 mg	37001137/5.2/0011	Registered	S3	None
Bisohexal 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	37051637/5.2/0516	Registered	S3	None
Bisohexal 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	37051737/5.2/0517	Registered	S3	None
Bisoprolol unicorn 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5Tablets	38005038/5.2/0050Approved 6 December 2023	Registered	S3	PI PIL
Bilocor 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10Tablets	38005138/5.2/0051Approved 18 October 2024	Registered	S3	PI PIL
Bisoprolol unicorn 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10Tablets	38005238/5.2/0052Approved 6 December 2023	Registered	S3	PI PIL
Bilocor 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5Tablets	38005338/5.2/0053Approved 18 October 2024	Registered	S3	PI PIL
Betacor 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5Film-coated tablets	38008038/5.2/0080Approved 27 October 2022	Registered	S3	PI PIL
Betacor 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10Film-coated tablets	38008138/5.2/0081Approved 27 October 2022	Registered	S3	PI PIL
Bisoprolol 5 biotech EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	38010538/5.2/0105	Registered	S3	None
Bisoprolol 10 biotech EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	38010638/5.2/0106	Registered	S3	None
Ziapro 5 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5 mg	41072041/5.2/0720	Cancelled	S3	None
Ziapro 10 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10 mg	41073941/5.2/0739	Cancelled	S3	None
Bisozyd 5 EACH TABLER CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	42084742/5.2/0847	Registered	S3	None
Bisozyd 10 EACH TABLER CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	42084842/5.2/0848	Registered	S3	None
Prosib 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	45007145/5.2/0071	Registered	S3	None
Prosib 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	45007245/5.2/0072	Registered	S3	None
Bislo 5 EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	45012845/5.2/0128	Registered	S3	None
Bislo 10 EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	45012945/5.2/0129	Registered	S3	None
Mylan bisoprolol 5 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5 mg	45052545/5.2/0525	Registered	S3	None
Mylan bisoprolol 10 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10 mg	45052645/5.2/0526	Registered	S3	None
Bisbeta 2,5 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 2,5 mg	2,5 mg	45078945/5.2/0789	Registered	S3	None
Bisbeta 5 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5 mg	45079045/5.2/0790	Registered	S3	None
Bisbeta 10 MG EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10 mg	45079145/5.2/0791	Registered	S3	None
Bisoprolol 2,5 unimed EACH TABLET CONTAINS :BISOPROLOL FUMARATE 2,5 mg	2,5	45079245/5.2/0792	Registered	S3	None
Bisoprolol 5 unimed EACH TABLET CONTAINS: BISOPROLOL FUMARATE 5,0 mg	5	45079345/5.2/0793	Registered	S3	None
Retocar 10 MG tablets EACH TABLET CONTAINS :BISOPROLOL FUMARATE 10,0 mg	10 mgTablets	45079445/5.2/0794	Registered	S3	None
Pentocor 5 MG tablets EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5 mgTablets	45086445/5.2/0864	Registered	S3	None
Pentocor 10 MG tablets EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10 mgTablets	45086545/5.2/0865	Registered	S3	None
Presese 5 MG tablets EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5 mgTablets	45086645/5.2/0866	Registered	S3	None
Presese 10 MG tablets EACH TABLET CONTAINS:BISOPROLOL FUMARATE 10,0 mg	10 mgTablets	45086745/5.2/0867	Registered	S3	None
Bisoprolol 5 kiara EACH TABLET CONTAINS BISOPROLOL FUMARATE 5,0 mg	5	46039046/5.2/0390	Registered	S3	None
Bisoprolol 10 kiara EACH TABLET CONTAINS BISOPROLOL FUMARATE 10,0 mg	10	46039146/5.2/0391	Registered	S3	None
Bisoprolol 2,5 accord EACH TABLET CONTAINS: BISOPROLOL 2,5 mg	2,5	47014847/6.1/0148	Registered	S3	None
Bisoprolol 5 accord EACH TABLET CONTAINS: BISOPROLOL 5,0 mg	5	47014947/6.1/0149	Registered	S3	None
Bisoprolol 10 accord EACH TABLET CONTAINS: BISOPROLOL 10,0 mg	10	47015047/6.1/0150	Registered	S3	None
Presicard 2,5 EACH TABLET CONTAINS: BISOPROLOL 2,5 mg	2,5	47015147/6.1/0151	Registered	S3	None
Presicard 5 EACH TABLET CONTAINS: BISOPROLOL 5,0 mg	5	47015247/6.1/0152	Registered	S3	None
Presicard 10 EACH TABLET CONTAINS: BISOPROLOL 10,0 mg	10	47015347/6.1/0153	Registered	S3	None
Emcor 2,5 MG EACH TABLET CONTAINS: BISOPROLOL FUMARATE 2,5 m	2,5 mg	51102151/6.1/1021	Registered	S3	None
Emcor 10 MG EACH TABLET CONTAINS: BISOPROLOL FUMARATE 10,0 mg	10 mg	51102351/6.1/1023	Registered	S3	None
Rupro 5 Each Tablet contains: Bisoprolol Fumarate 5,0 mg	5	57033757/5.2/0337	Registered	S3	None
Rupro 10 Each Tablet contains: Bisoprolol Fumarate 10,0 mg	10	57033857/5.2/0338	Registered	S3	None
Concor 5 tablets EACH TABLET CONTAINS BISOPROLOL 5 mg	5Tablets	V0303V/5.2/303	Registered	S3	None
Concor 10 tablets EACH TABLET CONTAINS BISOPROLOL 10 mg	10Tablets	V0304V/5.2/304	Registered	S3	None

Regulatory status

Where S3 sits on the scale

S0S1S2S3S4S5S6S7S8

Needs a doctor's prescription, dispensed by a pharmacist.

Schedule 3 medicines can only be sold on a prescription from an authorised prescriber, such as a doctor or dentist. A pharmacist dispenses the medicine once they have the written prescription, or a verbal instruction from a prescriber they know. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S3, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Bisoprolol fumarate

S3: Bisoprolol
Consolidated Schedules 06 July 2026, line 3221

Pharmacological class: Cardiac stimulants. (class 6.1)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsBisoprolol unicorn 5, Unicorn Pharmaceuticals (Pty) Ltd Patient information leaflet (PIL)For patients and carersBisoprolol unicorn 5, Unicorn Pharmaceuticals (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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