Betamethasone

Sold as Lenovate, Betanoid, Adco-betamethasone, Topivate, Steromien /stroop, Repivate, Pharma-q betamethasone, Vari-betamethasone, Betanoid co, Betsolan, Betsolan soluble, Celestone soluspan, Betnelan, Betnesol, Celestone, Betnesol eye ear and nose, Betnesol eye, Persivate, Lenasone

S4Read from the PI-PIL document and verified

C₂₂H₂₉FO₅392.50 g/mol

(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

Drag to rotate. Structure from PubChem CID 9782.

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Registration

Applicants: 10
Registrations: 23
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Pharmacare limited û woodmeadCertificate held by Pharmacare limited1 of 12 cancelled	Lenovate, Betanoid, Steromien /stroop, Betanoid co, Betnesol eye ear and nose, Betnesol eye, Persivate, Lenasone	ointment, 0,60 mg /5 ml, cream, 0,5 mg, 4 mg/ml, syrup/stroop, ,, 5 mg/5 g	270308, 270491, 270493, 270543, 300324, 310548, 500431, H1257, H1259, L0382, L0395, X0361	S4	PI PIL
Adcock ingram limitedCancelled	Adco-betamethasone	cream	300252	Not determined	None
FDC SA (Pty) Ltd	Topivate	Not stated	300458	Not determined	None
Cipla Medpro (Pty) Ltd	Repivate	Not stated	310688	Not determined	None
Pharma-q Holdings (Pty) Ltd	Pharma-q betamethasone	4 mg/1 ml	320338	Not determined	None
Barrs Pharmaceutical Industries (Pty) Ltd	Vari-betamethasone	cream	340430	Not determined	None
Schering-plough (Pty) Ltd	Betsolan, Betsolan soluble	injection	83/563, 83/564	Not determined	None
Organon South Africa (Pty) Ltd	Celestone soluspan	Not stated	G2963	Not determined	None
Glaxosmithkline South Africa (Pty) Limited	Betnelan, Betnesol	tablets, injection	G3084, G3085	Not determined	None
Msd (Pty) LtdCancelled	Celestone	Not stated	G3235	S4	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Lenovate ointment EACH 5 G OINTMENT CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO 5 MG BETAMETHASONE	Ointment	27030827/13.4.1/0308	Registered	Not determined	None
Betanoid syrup EACH 5 ml SYRUP CONTAINS BETAMETHASONE 0,6 mg	0,60 mg /5 mlSyrup	27049127/21.5.1/0491Approved 4 April 2024	Registered	S4	PI PIL
Lenovate cream EACH 5 g CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO 5 mg BETAMETHASONE	Cream	27049327/13.4.1/0493	Registered	Not determined	None
Betanoid tablets EACH TABLET CONTAINS BETAMETHASONE 0,5 mg	0,5 mgTablets	27054327/21.5.1/0543Approved 26 November 2024	Registered	S4	PI PIL
Adco-betamethasone cream EACH 5 g CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO 5,0 mg BETAMETHASONE	Cream	30025230/13.4.1/0252	Cancelled	Not determined	None
Betanoid injection 4 mg/ml EACH 1 ml LIQUID CONTAINS BETAMETHASONE SODIUM PHOSPHATE EQUIVALENT TO 4,0 mg BETAMETHASONE	4 mg/mlInjection	30032430/21.5.1/0324	Registered	Not determined	None
Topivate EACH 15,0 g CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO BETAMETHASONE 15,0 mg	Not listed	30045830/13.4.1/0458	Registered	Not determined	None
Steromien syrup/stroop EACH 5 ml SYRUP CONTAINS BETAMETHASONE 0,60 mg	Syrup/stroop	31054831/21.5.1/0548	Cancelled	Not determined	None
Repivate EACH 15,0 g CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO BETAMETHASONE 15,0 mg	Not listed	31068831/13.4.1/0688	Registered	Not determined	None
Pharma-q betamethasone injection 4 mg/1 ML EACH 1,0 ml SOLUTION CONTAINS BETAMETHASONE SODIUM PHOSPHATE EQUIVALENT TO BETAMETHASONE 4,0 mg	4 mg/1 mlInjection	32033832/21.5.1/0338	Registered	Not determined	None
Vari-betamethasone cream EACH 100,0 g CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO BETAMETHASONE 0,1 g	Cream	34043034/13.4.1/0430	Registered	Not determined	None
Betanoid co EACH 1,0 ML CONTAINS: BETAMETHASONE SODIUM PHOSPHATE EQUIVALENT TO BETAMETHASONE (IN SOLUTION) 3,0 mg BETAMETHASONE ACETATE ( IN SUSPENSION) 3,0 mg	Not listed	50043150/21.5.1/0431	Registered	S4	None
Betsolan injection EACH 1 ml SOLUTION CONTAINS BETAMETHASONE A 2 mg	Injection	83/563	Old Medicine	Not determined	None
Betsolan soluble injection EACH 1 ml SOLUTION CONTAINS BETAMETHASONE SODIUM PHOSPHATE A EQUIVALENT TO BETAMETHASONE 2,0 mg	Injection	83/564	Old Medicine	Not determined	None
Celestone soluspan EACH ML SONTAINS BETAMETHASONE ACETATE A 3,0 MG BETAMETHASONE SODIUM PHOSPHATE A 3,0 MG	Not listed	G2963	Old Medicine	Not determined	None
Betnelan tablets EACH TABLET CONTAINS BETAMETHASONE A 0,5 MG	Tablets	G3084	Old Medicine	Not determined	None
Betnesol injection EACH ML OF SOLUTION CONTAINS BETAMETHASONE A 4,0 MG	Injection	G3085	Old Medicine	Not determined	None
Celestone EACH 1 ML CONTAINS BETAMETHASONE SODIUM PHOSPHATE A 5,3 MG	Not listed	G3235	Cancelled	S4	None
Betnesol eye , ear and nose drops EACH 100 ml CONTAINS BETAMETHASONE SODIUM PHOSPHATE A 100,0 mg	,Drops	H1257	Old Medicine	S4	None
Betnesol eye ointment EACH 100 g CONTAINS BETAMETHASONE SODIUM PHOSPHATE A 0,1 g	Ointment	H1259	Old Medicine	S4	None
Persivate EACH 5 G CREAM CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO 5 MG BETAMETHASONE	Not listed	L0382L/13.4.1/382	Registered	Not determined	None
Persivate ointment EACH 5 G OINTMENT CONTAINS BETAMETHASONE VALERATE EQUIVALENT TO BETAMETHASONE 5 MG	5 mg/5 gCream, ointment	L0395L/13.4.1/395Approved 1 May 2024	Registered	S4	PI PIL
Lenasone injection 4 mg/ml EACH 1 ml AMPOULE CONTAINS BETAMETHASONE SODIUM PHOSPHATE EQUIVALENT TO BETAMETHASONE 4 mg	4 mg/mlInjection	X0361X/21.5.1/361	Registered	Not determined	None

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Betamethasone

S4: Betamethasone
Consolidated Schedules 06 July 2026, line 5481
S3: Calcipotriol
Consolidated Schedules 06 July 2026, line 3258

Pharmacological class: Corticosteroids and analogues. (class 21.5.1)

Matched through the component Calcipotriol.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Betanoid syrup, Pharmacare limited û woodmead is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsBetanoid syrup, Pharmacare limited û woodmead Patient information leaflet (PIL)For patients and carersBetanoid syrup, Pharmacare limited û woodmead

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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