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Apixaban

Sold as Eliquis, Apixaban pfizer, Zyquis, Clotixar, Apixaban accord, Eplipix, Fibranix, Apixaban DRL, Trearent, Apithromb, Apixaban lebasi, Pixeclot, Apixaban austell, Xarhib, Xarpix, Apixaban sandoz, Eliqmak, Apixaban PD, Innoklod, Pixulant, Apixaban cipla

S4
Loading the molecular structure
C25H25N5O4459.50 g/mol

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[5,4-c]pyridine-3-carboxamide

Drag to rotate. Structure from PubChem CID 10182969.

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Registration

Applicants
13
Registrations
42
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Pfizer Laboratories (Pty) LtdEliquis, Apixaban pfizer2,5 mg, 5 mg470463, 470464, 470465, 470466S4None
Zydus Healthcare (Pty) LtdCertificate held by Zydus Healthcare SA (Pty) LtdZyquis, Clotixar2,5 / 5 mg550053, 550054, 550055.053, 550056.054S4PIPIL
Accord Healthcare (Pty) LtdApixaban accord2,5, 5550372, 550373S4None
Ranbaxy Pharmaceutical (Pty) LtdCertificate held by Ranbaxy Pharmaceuticals (Pty) LtdEplipix2,5550549S4PIPIL
Ranbaxy Pharmaceuticals (Pty) LtdEplipix5550550S4PIPIL
Cipla Medpro (Pty) LtdFibranix, Pixulant, Apixaban cipla2,5, 5560026, 560027, 590208, 590209, 590210.208, 590211.209S4None
Dr Reddyæs Laboratories (Pty) LtdApixaban DRL2,5, 5560106, 560107S4None
Pps Pharmaceuticals (Pty) LtdTrearent, Apithromb, Apixaban lebasi2,5, 5560355, 560356, 560357.355, 560358.356, 560359.355, 560360.356S4None
Austell Pharmaceuticals (Pty) LtdPixeclot, Apixaban austell2,5 mg, 5 mg560419, 560420, 560421.419, 560422.420S4None
Sandoz South Africa (Pty) LtdXarhib, Xarpix, Apixaban sandoz2,5, 5560625, 560626, 560627.625, 560628.626, 560629.625, 560630.626S4None
Macleods Pharmaceuticals SA (Pty) LtdEliqmak2,5, 5570020, 570021S4None
Pharma Dynamics (Pty) LtdApixaban PD2,5 mg, 5 mg570106, 570107S4None
Innovata pharmaceuticalsCertificate held by Innovata Pharmaceuticals (Pty) LtdInnoklod2,5, 5580046, 580047S4PIPIL

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Eliquis 2,5 MG

EACH TABLET CONTAINS:APIXABAN 2,5 mg

2,5 mg47046347/8.2/0463RegisteredS4None
Eliquis 5 MG

EACH TABLET CONTAINS: APIXABAN 5,0 mg

5 mg47046447/8.2/0464RegisteredS4None
Apixaban 2,5 MG pfizer

EACH TABLET CONTAINS:APIXABAN 2,5 mg

2,5 mg47046547/8.2/0465RegisteredS4None
Apixaban 5 MG pfizer

EACH TABLET CONTAINS:APIXABAN 5,0 mg

5 mg47046647/8.2/0466RegisteredS4None
Zyquis 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5 / 5 mgFilm-coated tablets.55005355/8.2/0053Approved 18 December 2025RegisteredS4PIPIL
Zyquis 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

2,5 / 5 mgFilm-coated tablets.55005455/8.2/0054Approved 18 December 2025RegisteredS4PIPIL
Clotixar 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5 / 5 mgFilm-coated tablets.550055.05355/8.2/0055.053Approved 18 December 2025RegisteredS4PIPIL
Clotixar 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

2,5 / 5 mgFilm-coated tablets.550056.05455/8.2/0056.054Approved 18 December 2025RegisteredS4PIPIL
Apixaban 2,5 accord

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,555037255/8.2/0372RegisteredS4None
Apixaban 5 accord

EACH TABLET CONTAINS APIXABAN 5,0 mg

555037355/8.2/0373RegisteredS4None
Eplipix 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5Film-coated tablets55054955/8.2/0549Approved 12 May 2025RegisteredS4PIPIL
Eplipix 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

5Film-coated tablets55055055/8.2/0550Approved 12 May 2025RegisteredS4PIPIL
Fibranix 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,556002656/8.2/0026RegisteredS4None
Fibranix 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

556002756/8.2/0027RegisteredS4None
Apixaban 2,5 DRL

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,556010656/8.2/0106RegisteredS4None
Apixaban 5 DRL

EACH TABLET CONTAINS APIXABAN 5,0 mg

556010756/8.2/0107RegisteredS4None
Trearent 2,5

EACH TABLET CONTAINS: APIXABAN 2,5 mg

2,556035556/8.2/0355RegisteredS4None
Trearent 5

EACH TABLET CONTAINS: APIXABAN 5,0 mg

556035656/8.2/0356RegisteredS4None
Apithromb 2,5

EACH TABLET CONTAINS: APIXABAN 2,5 mg

2,5560357.35556/8.2/0357.355RegisteredS4None
Apithromb 5

EACH TABLET CONTAINS: APIXABAN 5,0 mg

5560358.35656/8.2/0358.356RegisteredS4None
Apixaban 2,5 lebasi

EACH TABLET CONTAINS: APIXABAN 2,5 mg

2,5560359.35556/8.2/0359.355RegisteredS4None
Apixaban 5 lebasi

EACH TABLET CONTAINS: APIXABAN 5,0 mg

5560360.35656/8.2/0360.356RegisteredS4None
Pixeclot 2,5 MG

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5 mg56041956/8.2/0419RegisteredS4None
Pixeclot 5 MG

EACH TABLET CONTAINS APIXABAN 5,0 mg

5 mg56042056/8.2/0420RegisteredS4None
Apixaban 2,5 MG austell

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5 mg560421.41956/8.2/0421.419RegisteredS4None
Apixaban 5 MG austell

EACH TABLET CONTAINS APIXABAN 5,0 mg

5 mg560422.42056/8.2/0422.420RegisteredS4None
Xarhib 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,556062556/8.2/0625RegisteredS4None
Xarhib 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

556062656/8.2/0626RegisteredS4None
Xarpix 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5560627.62556/8.2/0627.625RegisteredS4None
Xarpix 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

5560628.62656/8.2/0628.626RegisteredS4None
Apixaban 2,5 sandoz

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5560629.62556/8.2/0629.625RegisteredS4None
Apixaban 5 sandoz

EACH TABLET CONTAINS APIXABAN 5,0 mg

5560630.62656/8.2/0630.626RegisteredS4None
Eliqmak 2,5

Each Tablet contains: Apixaban 2,5 mg

2,557002057/8.2/0020RegisteredS4None
Eliqmak 5

Each Tablet contains: Apixaban 5,0 mg

557002157/8.2/0021RegisteredS4None
Apixaban 2,5 MG PD

Each Tablet contains: Apixaban 2,5 mg

2,5 mg57010657/8.2/0106RegisteredS4None
Apixaban 5 MG PD

Each Tablet contains: Apixaban 5 mg

5 mg57010757/8.2/0107RegisteredS4None
Innoklod 2,5

EACH TABLET CONTAINS APIXABAN 2,5 mg

2,5Film-coated tablets58004658/8.2/0046Approved 26 March 2024RegisteredS4PIPIL
Innoklod 5

EACH TABLET CONTAINS APIXABAN 5,0 mg

5Film-coated tablets58004758/8.2/0047Approved 26 March 2024RegisteredS4PIPIL
Pixulant 2,5

EACH TABLET CONTAINS: APIXABAN 2,5 mg

2,559020859/8.2/0208RegisteredS4None
Pixulant 5

EACH TABLET CONTAINS: APIXABAN 5,0 mg

5590209RegisteredS4None
Apixaban 2,5 cipla

EACH TABLET CONTAINS: APIXABAN 2,5 mg

2,5590210.20859/8.2/0210.208RegisteredS4None
Apixaban 5 cipla

EACH TABLET CONTAINS: APIXABAN 5,0 mg

5590211.20959/8.2/0211.209RegisteredS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Apixaban

  • S4: Apixaban

    Consolidated Schedules 06 July 2026, line 5323

Pharmacological class: Anticoagulants. (class 8.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Zyquis 2,5, Zydus Healthcare (Pty) Ltd is scheduled S4 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsZyquis 2,5, Zydus Healthcare (Pty) LtdPatient information leaflet (PIL)For patients and carersZyquis 2,5, Zydus Healthcare (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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