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Ampicillin

Sold as Amycil, Amycil s, Amycil sf, Dyna-ampicil, Xiapen, Be-ampicil, Xiapen s, Xiapen sf, Ampicillin unimed, Ampicillin ipharma, AURO ampicillin, Auro-ampicillin, Ropen, Nolix, Trycosil, Amiptras, Ampill-vet, Petercillin s, Petercillin sf, Petercillin, Ampicillin-fresenius, A-lennon ampicillin, Famicillin, Ampil c, Spectracil c, Spectracil sf, Ampil s, Ampil sf, Penrite s, Spectracil s, Penrite, M-p-cil, Dyna-ampcil, Excillin

S4
Loading the molecular structure
C16H19N3O4S349.40 g/mol

(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Drag to rotate. Structure from PubChem CID 6249.

Background

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Registration

Applicants
18
Registrations
53
Schedule source
Consolidated Schedules 06 July 2026

Applicants and registrations

ApplicantBrandsDosagesRegistrationsScheduleLeaflets
Mediscience (Pty) LtdCancelledAmycil, Amycil s, Amycil sf250270016, 270017, 270018S4None
Dynamed Registrations (Pty) LtdCancelledDyna-ampicil125 mg270336S4None
Viatris South Africa (Pty) LtdXiapen, Xiapen s, Xiapen sf500280660, 290153, 290154S4None
Ranbaxy Pharmaceutical (Pty) Ltd1 of 3 cancelledBe-ampicil250mg, 500 mg290127, 290128, X0098S4None
Unimed Healthcare (Pty) LtdAmpicillin unimed250, 500300247, 300248S4None
Ipharma (Pty) LtdAmpicillin ipharma500 mg370223S4None
Aurogen South Africa (Pty) Ltd9 of 11 cancelledAURO ampicillin, Auro-ampicillin, Ropen, Nolix, Trycosil1 g, 250 mg, 500 mg, 1000 mg410122, 410123, 420783, 420784, 420785, 450782, 450783, 450784, 450785, 450786, 450787S4None
Phenix SA (Pty) LtdAmiptras20083/235S4None
Logos Agvet (Pty) LtdAmpill-vet125 mg, 400 mg83/526, 83/846S4None
Pharmacare limited û woodmeadCancelledPetercillin s, Petercillin sf, Petercillin, A-lennon ampicillin, Penrite s, Penrite125, 250, 250 mg/5 ML, 500H0020, H0021, H0022, H0023, J0139, Q0240, V0116S4None
Bodene (Pty) Ltd Trading As IntramedCancelledAmpicillin-fresenius1 g, 5 g, 100 mgH0024, H0027, H0028S4None
Fresenius Kabi South Africa (Pty) LtdAmpicillin-fresenius250 mg, 500 mgH0025, H0026S4None
Genpharm Pharmaceuticals (1993) (Pty) LtdCancelledFamicillin1 g, 250 mg, 500 mgJ0450, J0451, J0452S4None
Alliance Pharma (Pty) Ltd5 of 7 cancelledAmpil c, Spectracil c, Spectracil sf, Ampil s, Ampil sf, Spectracil s125, 250, 500K0333, K0334, L0094, L0095, L0410, L0411, R0312S4None
Innovata pharmaceuticalsM-p-cil250 mgY0050S4None
Ascendis Pharma (Pty) LtdCancelledDyna-ampcilNot statedY0241S4None
Be-tabs Pharmaceuticals (Pty) LtdCancelledBe-ampicil250 mgZ0103S4None
Adcock ingram limitedCancelledExcillin125 mgZ0405S4None

Variants

ProductStrength and formRegistrationStatusScheduleLeaflets
Amycil 250

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

25027001627/20.1.2/0016CancelledS4None
Amycil s

EACH 5 ML CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 125 mg AMPICILLIN

Not listed27001727/20.1.2/0017CancelledS4None
Amycil sf

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

Not listed27001827/20.1.2/0018CancelledS4None
Dyna-ampicil 125 mg*

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 125 mg AMPICILLIN

125 mg27033627/20.1.1/0336CancelledS4None
Xiapen 500

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE 577,4 mg EQUIVALENT TO 500 mg AMPICILLIN

50028066028/20.1.1/0660RegisteredS4None
Be-ampicil 250mg injection

VIALAMPICILLIN SODIUM 265 MG

250mgInjection29012729/20.1.2/0127RegisteredS4None
Be-ampicil 500 MG injection

VIALAMPICILLIN SODIUM 531 mg

500 mgInjection29012829/20.1.2/0128RegisteredS4None
Xiapen s

5 ML AMPICILLIN TRIHYDRATE 147,95 MG

Not listed29015329/20.1.2/0153RegisteredS4None
Xiapen sf

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE 295,89 mg EQUIVALENT TO 250 mg AMPICILLIN

Not listed29015429/20.1.2/0154RegisteredS4None
Ampicillin 250 injection unimed

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO 250,0 mg AMPICILLIN

250Injection30024730/20.1.2/0247RegisteredS4None
Ampicillin 500 injection unimed

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO 500 mg AMPICILLIN

500Injection30024830/20.1.2/0248RegisteredS4None
Ampicillin for injection 500 MG ipharma

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500,0 mg

500 mgFor injection37022337/20.1.2/0223RegisteredS4None
AURO ampicillin injection 500 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500,0 mg

500 mgInjection41012241/20.1.2/0122RegisteredS4None
Auro-ampicillin injection 1000 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 1000,0 mg

1000 mgInjection41012341/20.1.2/0123CancelledS4None
Ropen 250 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 250,0 mg

250 mg42078342/20.1.2/0783CancelledS4None
Ropen 500 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500,0 mg

500 mg42078442/20.1.2/0784RegisteredS4None
Ropen 1 g

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 1,0 g

1 g42078542/20.1.2/0785CancelledS4None
Nolix 250 MG injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 250,0 mg

250 mgInjection45078245/20.1.2/0782CancelledS4None
Nolix 500 MG injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500,0 mg

500 mgInjection45078345/20.1.2/0783CancelledS4None
Nolix 1 g injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 1000,0 mg

1 gInjection45078445/20.1.2/0784CancelledS4None
Trycosil 250 MG injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 250,0 mg

250 mgInjection45078545/20.1.2/0785CancelledS4None
Trycosil 500 MG injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500,0 mg

500 mgInjection45078645/20.1.2/0786CancelledS4None
Trycosil 1 g injection

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 1000,0 mg

1 gInjection45078745/20.1.2/0787CancelledS4None
Amiptras 200

EACH 1 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE A 200 mg

20083/235Old MedicineS4None
Ampill-vet tablets 125 MG

EACH TABLET CONTAINS AMPICILLIN TRIHYDRATE A EQUIVALENT TO 125 mg AMPICILLIN

125 mgTablets83/526Old MedicineS4None
Ampill-vet tablets 400 MG

EACH TABLET CONTAINS AMPICILLIN TRIHYDRATE A EQUIVALENT TO AMPICILLIN 400 mg

400 mgTablets83/846Old MedicineS4None
Petercillin s - 125

EACH 5 ml SUPPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 125 mg AMPICILLIN

- 125H0020H/20.1.2/20CancelledS4None
Petercillin sf - 250

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

- 250H0021H/20.1.2/21CancelledS4None
Petercillin 250

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

250H0022H/20.1.2/22CancelledS4None
Petercillin 500

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 500 mg AMPICILLIN

500H0023H/20.1.2/23CancelledS4None
Ampicillin-fresenius 100 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 100 mg

100 mgH0024H/20.1.2/24CancelledS4None
Ampicillin-fresenius 250 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 250 mg

250 mgH0025H/20.1.2/25RegisteredS4None
Ampicillin-fresenius 500 MG

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 500 mg

500 mgH0026H/20.1.2/26RegisteredS4None
Ampicillin-fresenius 1 g

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 1 g

1 gH0027H/20.1.2/27CancelledS4None
Ampicillin-fresenius 5 g

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO AMPICILLIN 5 g

5 gH0028H/20.1.2/28CancelledS4None
A-lennon ampicillin 250 mg/5 ML suspension

EACH 5 ml RECONSTITUTED SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

250 mg/5 MLSuspensionJ0139J/20.1.2/139CancelledS4None
Famicillin 250 mg*

EACH VIAL CONTAINS AMPICILLIN SODIUM 250 mg

250 mgJ0450J/20.1.2/450CancelledS4None
Famicillin 500 mg*

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO 500 mg AMPICILLIN

500 mgJ0451J/20.1.2/451CancelledS4None
Famicillin 1 g*

EACH VIAL CONTAINS AMPICILLIN SODIUM EQUIVALENT TO 1 000 mg AMPICILLIN

1 gJ0452J/20.1.2/452CancelledS4None
Ampil c 250

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

250K0333K/20.1.2/333CancelledS4None
Ampil c 500

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 500 mg AMPICILLIN

500K0334K/20.1.2/0334CancelledS4None
Spectracil c 250

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

250L0094L/20.1.2/94CancelledS4None
Spectracil sf 250

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250,0 mg AMPICILLIN

250L0095L/20.1.2/95CancelledS4None
Ampil s 125

EACH 5 ml SUPENSION CONTAINS AMPICILLIN TRIHYDRATE 125 mg

125L0410L/20.1.2/410RegisteredS4None
Ampil sf 250

EACH 5 ml SUPENSION CONTAINS AMPICILLIN TRIHYDRATE 250 mg

250L0411L/20.1.2/411RegisteredS4None
Penrite 250 s

EACH 5 ml SUPSENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO AMPICILLIN 250 mg

250Q0240Q/20.1.2/240CancelledS4None
Spectracil s 125

EACH 5 ml CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 125,0 mg AMPICILLIN

125R0312R/20.1.2/312CancelledS4None
Penrite 500

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO AMPICILLIN 500 mg

500V0116V/20.1.2/116CancelledS4None
Be-ampicil

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO 250 mg AMPICILLIN

Not listedX0098X/20.1.2/98CancelledS4None
M-p-cil 250 MG capsules

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO AMPICILLIN 250 mg

250 mgCapsulesY0050Y/20.1.2/50RegisteredS4None
Dyna-ampcil

EACH CAPSULE CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO AMPICILLIN 250 mg

Not listedY0241Y/20.1.2/241CancelledS4None
Be-ampicil 250 mg*

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE 250 mg AMPICILLIN

250 mgZ0103Z/20.1.2/103CancelledS4None
Excillin 125 MG

EACH 5 ml SUSPENSION CONTAINS AMPICILLIN TRIHYDRATE EQUIVALENT TO AMPICILLIN 125 mg

125 mgZ0405Z/20.1.2/405CancelledS4None

Regulatory status

Where S4 sits on the scale

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

Consolidated Schedules listings for Ampicillin trihydrate equivalent to ampicillin

  • S4: Ampicillin

    • except when listed elsewhere in the Schedules and except intra-mammary preparations thereof, containing tracer dye(s) and intended for the treatment of mastitis in cattle and registered in terms of the provisions of the Fertilizers, Farm Feeds, Agricultural Remedies and Stock Remedies Act, 1947. (Act 36 of 1947)

    Consolidated Schedules 06 July 2026, lines 5240 to 5242

Pharmacological class: Penicillins. (class 20.1.2)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

SAHPRA has not published a professional information or patient information leaflet for this product.

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