Alprazolam

Sold as Xanor, Biozane, Anxirid, Azor, Xanor sr, Adco-alzam, Adco alzam, Zopax, Apotex-alprazolam, Alprazolam biotech, Xanolam, Coprax, Propan alprazolam, Alprazolam unicorn, Mylan alprazolam, Adco-alprazolam, Novapraz xr

C₁₇H₁₃ClN₄308.80 g/mol

8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Drag to rotate. Structure from PubChem CID 2118.

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Registration

Applicants: 10
Registrations: 39
Schedule source: Consolidated Schedules 06 July 2026

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Viatris Healthcare (Pty) Ltd	Xanor, Xanor sr, Mylan alprazolam	0,25 mg, 0,5 mg, 1,0 mg, 2,0 mg	270096, 290504, 290505, 290506, 320323, 320372, 320373, M0233, M0234	S5	None
Biotech Laboratories (Pty) Ltd	Biozane, Alprazolam biotech	0,5 mg, 1 mg, 10 mg/200 mg/350 mg	280001, 280002, 310012, 310014	S5	PI PIL
Pharmacare limited û woodmead2 of 5 cancelled	Anxirid, Azor	0,25, 0,5 mg, 1,0 mg	280088, 280113, 290180, 290181, 290182	S5	None
Adcock ingram limited3 of 9 cancelled	Adco-alzam, Adco alzam, Propan alprazolam, Alprazolam unicorn, Adco-alprazolam	0,25 mg, 0,5 mg, 1,0 mg, 1 mg	300211, 300212, 300213, 320153, 320154, 320155, 330486, 330487, 330488	S5	None
Cipla Medpro (Pty) LtdCancelled	Zopax	0,25, 0,5, 1,0	300264, 300357, 300358	S5	None
Apotex SA (Pty) LtdCancelled	Apotex-alprazolam	0,25 mg	310013	S5	None
Garec (Pty) LtdCancelled	Xanolam	0,5 mg	310015	S5	None
Pharma-q Holdings (Pty) Ltd	Coprax	0,25, 0,5, 1,0	310240, 310241, 310242	S5	None
Novagen Pharma (Pty) LtdCertificate held by Novagen Pharma (Pty) Ltd.1 of 3 cancelled	Novapraz xr	0,5, 1, 2	510435, 510436, 510437	S5	PI PIL
Upjohn South Africa (Pty) Ltd	Xanor	1 mg	M0235	S5	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Xanor 2,0 MG EACH TABLET CONTAINS ALPRAZOLAM 2,0 mg	2,0 mg	27009627/2.6/0096	Registered	S5	None
Biozane 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mg	28000128/2.6/0001	Registered	S5	None
Biozane 1 MG EACH TABLET CONTAINS ALPRAZOLAM 1 mg	1 mg	28000228/2.6/0002	Registered	S5	None
Anxirid 1,0 MG tablets EACH TABLET CONTAINS ALPRAZOLAM 1 mg	1,0 mgTablets	28008828/2.6/0088	Cancelled	S5	None
Anxirid 0,5 MG tablets EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mgTablets	28011328/2.6/0113	Cancelled	S5	None
Azor - 0,25 EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	- 0,25	29018029/2.6/0180	Registered	S5	None
Azor-0,5 EACH TABLET CONTAINS ALPRAZOLAM 0,5 MG	0,5	29018129/2.6/0181	Registered	S5	None
Azor-1,0 EACH TABLET CONTAINS ALPRAZOLAM 1,0 MG	1,0	29018229/2.6/0182	Registered	S5	None
Xanor sr 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,50 mg	0,5 mg	29050429/2.6/0504	Registered	S5	None
Xanor sr 1,0 MG EACH TABLET CONTAINS ALPRAZOLAM 1 mg	1,0 mg	29050529/2.6/0505	Registered	S5	None
Xanor sr 2,0 MG EACH TABLET CONTAINS ALPRAZOLAM 2 mg	2,0 mg	29050629/2.6/0506	Registered	S5	None
Adco-alzam 0,5 MG EACH TABLET CONTAINS :ALPRAZOLAM 0,5 mg	0,5 mg	30021130/2.6/0211	Registered	S5	None
Adco-alzam 0,25 MG TABLET ALPRAZOLAM 0,25 MG	0,25 mg	30021230/2.6/0212	Registered	S5	None
Adco alzam 1,0 MG EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1,0 mg	30021330/2.6/0213	Registered	S5	None
Zopax 0,25 EACH TABLET CONTAINS: ALPRAZOLAM 0,25 mg	0,25	30026430/2.6/0264	Cancelled	S5	None
Zopax 0,5 EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5	30035730/2.6/0357	Cancelled	S5	None
Zopax 1,0 EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1,0	30035830/2.6/0358	Cancelled	S5	None
Biozane 0,25 EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	10 mg/200 mg/350 mgTablets	31001231/2.6/0012Approved 19 August 2025	Registered	S5	PI PIL
Apotex-alprazolam 0,25 MG EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25 mg	31001331/2.6/0013	Cancelled	S5	None
Alprazolam biotech 0,5 EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5	31001431/2.6/0014	Registered	S5	None
Xanolam 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mg	31001531/2.6/0015	Cancelled	S5	None
Coprax 0,25 EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25	31024031/2.6/0240	Registered	S5	None
Coprax 0,5 EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5	31024131/2.6/0241	Registered	S5	None
Coprax 1,0 EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1,0	31024231/2.6/0242	Registered	S5	None
Propan alprazolam 0,25 MG EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25 mg	32015332/2.6/0153	Registered	S5	None
Alprazolam unicorn 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mg	32015432/2.6/0154	Registered	S5	None
Alprazolam unicorn 1,0 MG EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1,0 mg	32015532/2.6/0155	Registered	S5	None
Mylan alprazolam 1,0 MG EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1,0 mg	32032332/2.6/0323	Registered	S5	None
Mylan alprazolam 0,25 MG EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25 mg	32037232/2.6/0372	Registered	S5	None
Mylan alprazolam 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mg	32037332/2.6/0373	Registered	S5	None
Adco-alprazolam 0,25 MG EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25 mg	33048633/2.6/0486	Cancelled	S5	None
Adco-alprazolam 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,50 mg	0,5 mg	33048733/2.6/0487	Cancelled	S5	None
Adco-alprazolam 1 MG EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1 mg	33048833/2.6/0488	Cancelled	S5	None
Novapraz xr 0,5	0,5Extended release tablets (xr)	51043551/2.6/0435Approved 5 March 2021	Registered	S5	PI PIL
Novapraz xr 1	1Extended release tablets (xr)	51043651/2.6/0436Approved 5 March 2021	Registered	S5	PI PIL
Novapraz xr 2 EACH TABLET CONTAINS: ALPRAZOLAM 2,0 mg	2Extended release tablets (xr)	51043751/2.6/0437Approved 5 March 2021	Cancelled	S5	PI PIL
Xanor 0,25 MG EACH TABLET CONTAINS ALPRAZOLAM 0,25 mg	0,25 mg	M0233M/2.6/233	Registered	S5	None
Xanor 0,5 MG EACH TABLET CONTAINS ALPRAZOLAM 0,5 mg	0,5 mg	M0234M/2.6/234	Registered	S5	None
Xanor 1 MG EACH TABLET CONTAINS ALPRAZOLAM 1,0 mg	1 mg	M0235M/2.6/235	Registered	S5	None

Regulatory status

Where S5 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only, with tighter controls on repeats.

Schedule 5 medicines need a prescription, and repeat dispensing is capped at six months in total; the prescriber must state upfront how many times, and at what intervals, it may be repeated. Extra limits apply to some uses: if it is being used for its anxiolytic, antidepressant, tranquillising or analgesic properties, it cannot be prescribed for longer than six months without a further consultation. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S5, matched to the Consolidated Schedules by ingredient, confidence high.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it.

Consolidated Schedules listings for Alprazolam

S5: Alprazolam
Consolidated Schedules 06 July 2026, line 9202

Pharmacological class: Tranquillisers. (class 2.6)

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Schedule verified from official documents

Schedule Verification

Biozane 0,25, Biotech Laboratories (Pty) Ltd is scheduled S5 in its official SAHPRA documents, read with 90% confidence.

Professional information (PI)For healthcare professionalsBiozane 0,25, Biotech Laboratories (Pty) Ltd Patient information leaflet (PIL)For patients and carersBiozane 0,25, Biotech Laboratories (Pty) Ltd

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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