Aciclovir

Sold as Adco-acyclovir topical, Adco-acyclovir, Zovirax, Cyclivex, Apo-acyclovir, Acyclovir biotech, Beta-vira topical, Lovire, Aspen acyclovir, Aciclovir sandoz, Acitop, Trio-acyclovir, Avirex, P & u aciclovir csv, Acitab dt, Aciclovir viatris, Acyrax I.V., Acyclovir PHARMC, Austell acyclovir, Zovirax iv

S4Read from the PI-PIL document and verified

C₈H₁₁N₅O₃225.20 g/mol

2-Amino-9-(2-hydroxyethoxymethyl)-1H-purin-6-one

Drag to rotate. Structure from PubChem CID 135398513.

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Registration

Applicants: 14
Registrations: 35
Schedule source: SAHPRA documentation

Applicants and registrations

Applicant	Brands	Dosages	Registrations	Schedule	Leaflets
Adcock ingram limited	Adco-acyclovir topical, Adco-acyclovir, Beta-vira topical	cream, 1 g, 200 mg	280369, 280552, 310549	Not determined	PI PIL
Glaxosmithkline South Africa (Pty) LimitedCertificate held by Gsk, Glaxosmithkline South Africa (Pty) Ltd2 of 4 cancelled	Zovirax, Zovirax iv	200 mg, 250mg, cream	290452, Q0164, R0271, S0236	S4	PI PIL
Pharmacare limited û woodmeadCertificate held by Pharmacare limited	Cyclivex, Aspen acyclovir	250 mg, 400 mg	310298, 320257	S4	PI PIL
Apotex SA (Pty) LtdCancelled	Apo-acyclovir	200 mg, 800 mg	310428, 310429	Not determined	None
Biotech Laboratories (Pty) Ltd	Acyclovir biotech, Acyrax I.V.	200 mg	310430, 480387	Not determined	None
Arya Pharma (Pty) LtdCancelled	Acyclovir biotech	800	310431	Not determined	None
Ranbaxy Pharmaceutical (Pty) Ltd	Lovire	200, 400, cream	320017, 320018, 340483	Not determined	None
Sandoz South Africa (Pty) Ltd	Aciclovir sandoz	200, 400	320378, 320379	Not determined	None
Cipla Medpro (Pty) LtdCertificate held by Cipla Medpro (Pty) Ltd.1 of 4 cancelled	Acitop, Acitab dt	50 mg, 200, 400, 800	320719, 380128, 380129, 380130	Not determined	PI PIL
Triomed (Pty) LtdCancelled	Trio-acyclovir, Avirex	200, 800, cream	330175, 330176, 330233, 330234	Not determined	None
Pfizer Laboratories (Pty) Ltd	P & u aciclovir csv	250 mg/10 ML, 500 mg/20 ml	350037, 350038	Not determined	None
Viatris South Africa (Pty) Ltd	Aciclovir viatris	250, 500	420069, 420070	Not determined	None
Pharmacorp (Pty) Ltd	Acyclovir PHARMC	200, 400	A390343, A390344	Not determined	None
Austell Pharmaceuticals (Pty) Ltd	Austell acyclovir	200 mg, 400 mg	A390345, A390346	Not determined	None

Variants

Product	Strength and form	Registration	Status	Schedule	Leaflets
Adco-acyclovir topical cream EACH 5 g CONTAINS ACICLOVIR 250 mg	Cream	28036928/20.2.8/0369	Registered	Not determined	None
Adco-acyclovir 200 MG EACH TABLET CONTAINS : ACICLOVIR 200 mg	200 mg	28055228/20.2.8/0552	Registered	Not determined	None
Zovirax 200 EACH TABLET CONTAINS ACICLOVIR 200 MG	200	29045229/20.2.8/0452	Cancelled	Not determined	None
Cyclivex 400 MG tablets EACH TABLET CONTAINS ACICLOVIR 400 mg	400 mgTablets	31029831/20.2.8/0298	Registered	Not determined	None
Apo-acyclovir 200 MG EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200 mg	31042831/20.2.8/0428	Cancelled	Not determined	None
Apo-acyclovir 800 MG EACH TABLET CONTAINS ACICLOVIR 800,0 MG	800 mg	31042931/20.2.8/0429	Cancelled	Not determined	None
Acyclovir biotech 200 MG EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200 mg	31043031/20.2.8/0430	Registered	Not determined	None
Acyclovir biotech 800 EACH TABLET CONTAINS ACICLOVIR 800,0 mg	800	31043131/20.2.8/0431	Cancelled	Not determined	None
Beta-vira topical cream EACH 1 g CREAM CONTAINS ACICLOVIR 5,0 mg	1 gCream.	31054931/20.2.8/0549Approved 2 December 2024	Registered	Not determined	PI PIL
Lovire 200 tablets EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200Tablets	32001732/20.2.8/0017	Registered	Not determined	None
Lovire 400 tablets EACH TABLET CONTAINS ACICLOVIR 400,0 mg	400Tablets	32001832/20.2.8/0018	Registered	Not determined	None
Aspen acyclovir 250 MG EACH 20,0 ml VIAL CONTAINS ACICLOVIR 250,0 mg	250 mgPowder for solution for infusion	32025732/20.2.8/0257Approved 18 February 2025	Registered	S4	PI PIL
Aciclovir sandoz 200 EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200	32037832/20.2.8/0378	Registered	Not determined	None
Aciclovir sandoz 400 EACH TABLET CONTAINS ACICLOVIR 400,0 mg	400	32037932/20.2.8/0379	Registered	Not determined	None
Acitop EACH 5,0 g CREAM CONTAINS ACICLOVIR 250,0 mg	50 mgCream.	32071932/20.2.8/0719Approved 3 February 2025	Registered	Not determined	PI PIL
Trio-acyclovir 200 EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200	33017533/20.2.8/0175	Cancelled	Not determined	None
Trio-acyclovir 800 EACH TABLET CONTAINS ACICLOVIR 800,0 mg	800	33017633/20.2.8/0176	Cancelled	Not determined	None
Trio-acyclovir cream EACH 100,0 g CREAM CONTAINS ACICLOVIR 5,0 g	Cream	33023333/20.2.8/0233	Cancelled	Not determined	None
Avirex cream EACH 100,0 g CREAM CONTAINS ACICLOVIR 5,0 g	Cream	33023433/20.2.8/0234	Cancelled	Not determined	None
Lovire cream EACH 1,0 g CREAM CONTAINS ACICLOVIR 50,0 mg	Cream	34048334/20.2.8/0483	Registered	Not determined	None
P & u aciclovir csv 250 mg/10 ML injection EACH 1,0 ml SOLUTION CONTAINS ACICLOVIR 25,0 mg	250 mg/10 MLInjection	35003735/20.2.8/0037	Registered	Not determined	None
P & u aciclovir csv 500 mg/20 ML injection EACH 1,0 ml SOLUTION CONTAINS ACICLOVIR 25,0 mg	500 mg/20 mlInjection	35003835/20.2.8/0038	Registered	Not determined	None
Acitab-400 dt EACH TABLET CONTAINS ACICLOVIR 400,0 mg	400	38012838/20.2.8/0128	Registered	Not determined	None
Acitab-200 dt each tablet CONTAINS ACICLOVIR 200,0 mg	200	38012938/20.2.8/0129	Registered	Not determined	None
Acitab-800 dt EACH TABLET CONTAINS ACICLOVIR 800,0 mg	800	38013038/20.2.8/0130	Cancelled	Not determined	None
Aciclovir 250 viatris EACH VIAL CONTAINS ACICLOVIR 250,0 mg	250	42006942/20.2.8/0069	Registered	Not determined	None
Aciclovir 500 viatris EACH VIAL CONTAINS ACICLOVIR 500,0 mg	500	42007042/20.2.8/0070	Registered	Not determined	None
Acyrax I.V. EACH 1,0 ml SOLUTION CONTAINS ACICLOVIR 25,0 mg	Not listed	48038748/20.2.8/0387	Registered	Not determined	None
Acyclovir 200 PHARMC EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200	A390343A39/20.2.8/0343	Registered	Not determined	None
Acyclovir 400 PHARMC EACH TABLET CONTAINS ACICLOVIR 400,0 mg	400	A390344A39/20.2.8/0344	Registered	Not determined	None
Austell acyclovir 200 MG EACH TABLET CONTAINS ACICLOVIR 200,0 mg	200 mg	A390345A39/20.2.8/0345	Registered	Not determined	None
Austell acyclovir 400 MG EACH TABLET CONTAINS ACICLOVIR 400,0 mg	400 mg	A390346A39/20.2.8/0346	Registered	Not determined	None
Zovirax iv EACH VIAL CONTAINS ACICLOVIR SODIUM EQUIVALENT TO ACICLOVIR 250 mg	250mgInjection	Q0164Q/20.2.8/164Approved 27 January 2023	Registered	S4	PI PIL
Zovirax cream EACH GRAM CONTAINS ACICLOVIR 50 MG	Cream	R0271R/20.2.8/271	Cancelled	Not determined	None
Zovirax suspension EACH 5 ml SUSPENSION CONTAINS ACICLOVIR 200 mg	200 mgSuspension.	S0236S/20.2.8/236Approved 31 October 2025	Registered	S4	PI PIL

Regulatory status

Where S4 sits on the scale

S0S1S2S3S4S5S6S7S8

Prescription-only medicine.

Schedule 4 covers most ordinary prescription medicines. You need a prescription from an authorised prescriber, such as a doctor or dentist, and a pharmacist dispenses it. Its price, name, pack size and strength can still be told to the public, as long as nothing links it to what it treats.

Schedule S4, read from the product's PI-PIL leaflet.

Who may supply: A pharmacist dispensing against a written or verbal prescription from an authorised prescriber; a veterinarian, who may also prescribe, compound or dispense it directly; a medical practitioner or dentist, who may prescribe it and may compound or dispense it directly only if licensed under section 22C(1)(a); manufacturers and wholesalers may supply people who may lawfully possess it; and, for animal treatment, a person practising a para-veterinary profession, on a veterinarian's written or verbal instruction.

This is an informational summary of the Medicines and Related Substances Act 101 of 1965 and its 2017 General Regulations. It is not medical advice and not legal advice. Always check the medicine's label, which carries the schedule number inside a square border, or ask a pharmacist if you are unsure.

SAHPRA documents

Professional information (PI)For healthcare professionalsBeta-vira topical cream, Adcock ingram limited Patient information leaflet (PIL)For patients and carersBeta-vira topical cream, Adcock ingram limited

These documents are provided by SAHPRA for informational purposes. Always consult with a healthcare professional for medical advice.

Research articles

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